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BTBnano SIGNED

Do Particle Properties Modulate bioaccumulation, Trophic Transfer and biomagnifications of engineered nanomaterials: Role of Particles size, shape and surface coating? - BTBnano

Total Cost €

EC-Contrib. €

Partnership

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BTBnano project word cloud

Explore the words cloud of the BTBnano project. It provides you a very rough idea of what is the project "BTBnano" about.

predicting heterogeneity spectroscopy biological mass enm protect intracellular model chronic ionic au size spectrometry magna laser concentration risk nanomedicine proper room fourier analyser trophic combination exposure metric cells measuring influence bioaccumulation chain aquatic chromatography thermogravimetric coupled quantified minimise food metal biomagnification quantification ablation single dose transfer me situ nanotubes climate function infrared daphnia shape icp walled gold danio systematically metrics matrices techniques surface line swcnts carbon particle rerio gas inductively novelty cell policy human biodiversity differentiate skills health enms transferable transform host particulate capacity ms nanotoxicology biodistribution risks training coating environment tissues plasma optimized btbnano sp quantify

Project "BTBnano" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITEIT LEIDEN Organization address address: RAPENBURG 70 city: LEIDEN postcode: 2311 EZ website: www.universiteitleiden.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	165˙598 €
EC max contribution	165˙598 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-EF-ST
Starting year	2018
Duration (year-month-day)	from 2018-03-01 to 2020-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITEIT LEIDEN UNIVERSITEIT LEIDEN Organization address address: RAPENBURG 70 city: LEIDEN postcode: 2311 EZ website: www.universiteitleiden.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (LEIDEN)	coordinator	165˙598.00

Map

Project objective

BTBnano will use state of the art knowledge and techniques to quantify single-walled carbon nanotubes (SWCNTs) and gold ENMs in cells and tissues. The objectives are to: (1) systematically quantify bioaccumulation and biodistribution of SWCNTs (as a function of size) and Au ENMs (as a function of size, shape and surface coating) in Daphnia magna and Danio rerio at chronic exposure conditions, (2) study the influence of particle size, shape and surface coating of Au ENMs and size of SWCNTs on their trophic transfer along an aquatic food chain, and (3) study the potential for biomagnification of SWCNTs and Au ENMs in the food chain when mass and particle number concentration are considered as dose metrics and develop a model for predicting biomagnification of ENMs based on the proper dose metric. Bioaccumulation and biomagnification of Au ENMs will be quantified by measuring mass and particle number concentration using inductively coupled plasma (ICP)-mass spectroscopy (MS) and single particle (sp)-ICP-MS. (sp)-ICP-MS will also be used to differentiate between ionic and particulate bioaccumulation of Au ENMs. Laser ablation-ICP-MS will be used to in situ quantify cell-to-cell heterogeneity of the intracellular distribution of Au ENMs. Combination of thermogravimetric analyser with fourier transform infrared and gas chromatography/mass spectrometry will be optimized for quantification of SWCNTs in tissues. The novelty of the project is in developing approaches for quantification of carbon-based and metal-based ENMs in biological matrices. BTBnano includes both training me in new advanced techniques and transferable skills and the transfer of knowledge to the host institution. Results have the potential capacity to support the ENM risk assessment and provide room for further studies in nanotoxicology and nanomedicine. This project is in line with the EU policy to protect the environment and to minimise risks to climate, human health and biodiversity.

Publications

List of publications.
year	authors and title	journal	last update
2019	Ekta Tiwari, Mithu Mondal, Nisha Singh, Nitin Kumar Khandelwal, Fazel;Fazel Abdolahpur Monikh, Gopala Krishna Darbha Effect of irrigation water type and other environmental parameters on CeO2 nanopesticide-clay colloid interactions published pages: , ISSN: 2050-7887, DOI: 10.1039/c9em00428a	Environmental Science: Processes & Impacts	2019-12-16
2019	Fazel Abdolahpur Monikh, Benjamin Fryer, Daniel Arenas-Lago, Martina G. Vijver, Gopala Krishna Darbha, Eugenia Valsami-Jones, Willie J. G. M. Peijnenburg A Dose Metrics Perspective on the Association of Gold Nanomaterials with Algal Cells published pages: , ISSN: 2328-8930, DOI: 10.1021/acs.estlett.9b00683	Environmental Science & Technology Letters	2019-12-16
2019	Fazel Abdolahpur Monikh, Daniel Arenas-Lago, Petr Porcal, Renato Grillo, Peng Zhang, Zhiling Guo, Martina G. Vijver, Willie J. G. M. Peijnenburg Do the joint effects of size, shape and ecocorona influence the attachment and physical eco(cyto)toxicity of nanoparticles to algae? published pages: 1-16, ISSN: 1743-5390, DOI: 10.1080/17435390.2019.1692381	Nanotoxicology	2019-12-16
2019	AFazelAbdolahpur Monikh, Nadine Grundschober, Stefan Romeijn, Daniel Arenas-Lago, Martina G.Vijver, WimJiskoot, Willie J.G.M.Peijnenburg Development of methods for extraction and analytical characterization of carbon-based nanomaterials (nanoplastics and carbon nanotubes) in biological and environmental matrices by asymmetrical flow field-flow fractionation published pages: 113304, ISSN: 0269-7491, DOI: 10.1016/j.envpol.2019.113304	Environmental Pollution	2019-10-29
2019	Daniel Arenas-Lago, Fazel Abdolahpur Monikh, Martina G. Vijver, Willie J.G.M. Peijnenburg Interaction of zero valent copper nanoparticles with algal cells under simulated natural conditions: Particle dissolution kinetics, uptake and heteroaggregation published pages: 133-140, ISSN: 0048-9697, DOI: 10.1016/j.scitotenv.2019.06.388	Science of The Total Environment 689	2019-09-11
2019	Fazel Abdolahpur Monikh, Latifeh Chupani, Martina G. Vijver, Marie VancovÃ¡, Willie J.G.M. Peijnenburg Analytical approaches for characterizing and quantifying engineered nanoparticles in biological matrices from an (eco)toxicological perspective: old challenges, new methods and techniques published pages: 1283-1293, ISSN: 0048-9697, DOI: 10.1016/j.scitotenv.2019.01.105	Science of The Total Environment 660	2019-06-03

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The information about "BTBNANO" are provided by the European Opendata Portal: CORDIS opendata.