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SENSITIVE SIGNED

Early Detection of cancer onset based on sensing field cancerization at the organ level

Total Cost €

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EC-Contrib. €

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Partnership

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Project "SENSITIVE" data sheet

The following table provides information about the project.

Coordinator
IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON 

Organization address
address: SORANOU EFESIOU 4
city: ATHINA
postcode: 115 27
website: www.bioacademy.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Project website http://www.sensitiveproject.eu
 Total cost 2˙965˙326 €
 EC max contribution 2˙965˙326 € (100%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-1-2016-2017
 Funding Scheme RIA
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON EL (ATHINA) coordinator 541˙812.00
2    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH DE (NEUHERBERG) participant 697˙876.00
3    RIVERD INTERNATIONAL BV NL (ROTTERDAM) participant 558˙125.00
4    ACADEMISCH ZIEKENHUIS GRONINGEN NL (GRONINGEN) participant 438˙781.00
5    UNIVERSIDAD CARLOS III DE MADRID ES (GETAFE (MADRID)) participant 362˙187.00
6    RAYFOS LTD UK (BASINGSTOKE) participant 231˙918.00
7    MARIOS LYMARAKIS KAI SIA EE EL (GERAKAS ATTIKI) participant 134˙625.00

Map

 Project objective

Cancer is a major cause of death worldwide. Gastrointestinal (GI) tract tumors are among the most common and deadliest ones. Despite progress in imaging and treatment, the social impact of these diseases is enormous. All parties in the health sector agree that prevention and/or early diagnosis is the most effective means to deal with cancer. Currently, cancer is identified most often when symptomatic or large enough to be visualized in body scans or when histological alterations are already present. What is lacking is an imaging method that could detect tissue changes that facilitate or predict tumor development at an early stage. These alterations, collectively referred to as “field cancerization” is an exciting field of study in cancer biology with profound ramifications in clinical practice. Molecular mechanisms underlying field cancerization are being studied and the advances in molecular biology facilitate these studies. Never in the past however, have these changes been sensed/measured by an imaging modality at the organ level. We thus propose the development of a multimodal microscopy platform that will allow sensing of Raman and scattering properties at the organ level, in order to identify molecular and structural fingerprints of early stage disease in the GI tract. Successful implementation will allow the development of an endoscope especially designed for this purpose that will be used to detect early stage cancer in humans.

 Deliverables

List of deliverables.
Data Management Plan Open Research Data Pilot 2020-02-07 15:50:22

Take a look to the deliverables list in detail:  detailed list of SENSITIVE deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Albert-Smet, Ignacio; Marcos-Vidal, Asier; Vaquero, Juan José; Desco, Manuel; Muñoz-Barrutia, Arrate; Ripoll, Jorge
Applications of Light-Sheet Microscopy in Microdevices
published pages: , ISSN: 1662-5129, DOI: 10.3389/fnana.2019.00001
Frontiers in Neuroanatomy 1 2020-02-05

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The information about "SENSITIVE" are provided by the European Opendata Portal: CORDIS opendata.

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