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AMR-TB SIGNED

Theoretical and computational investigation of tuberculosis antimicrobial resistance development based on extensive experimental library of mycobacterium strains

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "AMR-TB" data sheet

The following table provides information about the project.

Coordinator
ASTON UNIVERSITY 

Organization address
address: ASTON TRIANGLE
city: BIRMINGHAM
postcode: B4 7ET
website: www.aston.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 731˙400 €
 EC max contribution 731˙400 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2018
 Funding Scheme MSCA-RISE
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2023-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ASTON UNIVERSITY UK (BIRMINGHAM) coordinator 138˙000.00
2    INSTITUT BIOHIMII IM.O.V. PALLADINA NACIONALNOY AKADEMII NAUK UKRAINI UA (KYIV) participant 423˙200.00
3    TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV UA (KYIV) participant 87˙400.00
4    UNIVERSITA DEGLI STUDI DI MESSINA IT (MESSINA) participant 46˙000.00
5    UNIVERSITY OF SURREY UK (GUILDFORD) participant 27˙600.00
6    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 9˙200.00
7    ESCUELA POLITECNICA NACIONAL EC (QUITO) partner 0.00
8    FEDERAL STATE INSTITUTION SAINT PETERSBURG RESEARCH INSTITUTE OF PHTHISIOPULMONOLOGY OF THE FEDERAL AGENCY FOR HIGH TECHNOLOGY MEDICAL AID RU (SAINT PETERSBURG) partner 0.00
9    KURSK STATE UNIVERSITY RU (KURSK) partner 0.00
10    RIKEN THE INSTITUTE OF PHYSICAL ANDCHEMICAL RESEARCH JP (WAKO SHI SAITAMA) partner 0.00
11    SAINT PETERSBURG STATE UNIVERSITY RU (SAINT PETERSBURG) partner 0.00

Map

 Project objective

Multidrug resistance of Mycobacterium tuberculosis is declared a serious global threat by the World Health Organization. Our project aims at developing a comprehensive model of molecular mechanisms responsible for antimicrobial drug resistance of tuberculosis. Isoniazid is the main drug used for TB treatment, because it interacts with the bacterial catalase that leads to the bacterial death. The library of isoniazid resistant strains (over 100 different strains) will be used as experimental basis for building theoretical and computational models of the molecular processes leading to drug resistance of mutated bacteria. The model will be used for suggesting effective treatment targeting these mechanisms and overcoming the resistance. AMR-TB RISE will be used to utilise the expertise of highly specialised research groups of biologists, clinicians, biochemists, physicists, computer engineers, and mathematicians allowing the researches from these groups to work in multiple laboratories of the Consortium all over the world. Particular attention will be given to training the next generation of young researcher and forming tightly interconnected, long term collaboration devoted to solving the pressing global problem of antimicrobial resistance not only in TB, but in a wide spectrum of diseases.

 Deliverables

List of deliverables.
Project website and project Web 2.0 presence Other 2020-04-09 20:15:13

Take a look to the deliverables list in detail:  detailed list of AMR-TB deliverables.

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The information about "AMR-TB" are provided by the European Opendata Portal: CORDIS opendata.

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