AMR-TB SIGNED
Theoretical and computational investigation of tuberculosis antimicrobial resistance development based on extensive experimental library of mycobacterium strains
Total Cost €
0EC-Contrib. €
0Partnership
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Explore the words cloud of the AMR-TB project. It provides you a very rough idea of what is the project "AMR-TB" about.
Project "AMR-TB" data sheet
The following table provides information about the project.
| Coordinator |
ASTON UNIVERSITY
Organization address contact info |
| Coordinator Country | United Kingdom [UK] |
| Total cost | 731˙400 € |
| EC max contribution | 731˙400 € (100%) |
| Programme |
1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge) |
| Code Call | H2020-MSCA-RISE-2018 |
| Funding Scheme | MSCA-RISE |
| Starting year | 2019 |
| Duration (year-month-day) | from 2019-02-01 to 2023-01-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | ASTON UNIVERSITY | UK (BIRMINGHAM) | coordinator | 138˙000.00 |
| 2 | INSTITUT BIOHIMII IM.O.V. PALLADINA NACIONALNOY AKADEMII NAUK UKRAINI | UA (KYIV) | participant | 423˙200.00 |
| 3 | TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV | UA (KYIV) | participant | 87˙400.00 |
| 4 | UNIVERSITA DEGLI STUDI DI MESSINA | IT (MESSINA) | participant | 46˙000.00 |
| 5 | UNIVERSITY OF SURREY | UK (GUILDFORD) | participant | 27˙600.00 |
| 6 | AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS | ES (MADRID) | participant | 9˙200.00 |
| 7 | ESCUELA POLITECNICA NACIONAL | EC (QUITO) | partner | 0.00 |
| 8 | FEDERAL STATE INSTITUTION SAINT PETERSBURG RESEARCH INSTITUTE OF PHTHISIOPULMONOLOGY OF THE FEDERAL AGENCY FOR HIGH TECHNOLOGY MEDICAL AID | RU (SAINT PETERSBURG) | partner | 0.00 |
| 9 | KURSK STATE UNIVERSITY | RU (KURSK) | partner | 0.00 |
| 10 | RIKEN THE INSTITUTE OF PHYSICAL ANDCHEMICAL RESEARCH | JP (WAKO SHI SAITAMA) | partner | 0.00 |
| 11 | SAINT PETERSBURG STATE UNIVERSITY | RU (SAINT PETERSBURG) | partner | 0.00 |
Map
Project objective
Multidrug resistance of Mycobacterium tuberculosis is declared a serious global threat by the World Health Organization. Our project aims at developing a comprehensive model of molecular mechanisms responsible for antimicrobial drug resistance of tuberculosis. Isoniazid is the main drug used for TB treatment, because it interacts with the bacterial catalase that leads to the bacterial death. The library of isoniazid resistant strains (over 100 different strains) will be used as experimental basis for building theoretical and computational models of the molecular processes leading to drug resistance of mutated bacteria. The model will be used for suggesting effective treatment targeting these mechanisms and overcoming the resistance. AMR-TB RISE will be used to utilise the expertise of highly specialised research groups of biologists, clinicians, biochemists, physicists, computer engineers, and mathematicians allowing the researches from these groups to work in multiple laboratories of the Consortium all over the world. Particular attention will be given to training the next generation of young researcher and forming tightly interconnected, long term collaboration devoted to solving the pressing global problem of antimicrobial resistance not only in TB, but in a wide spectrum of diseases.
Deliverables
| Project website and project Web 2.0 presence | Other | 2020-04-09 20:15:13 |
Take a look to the deliverables list in detail: detailed list of AMR-TB deliverables.
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