The page lists 76 projects related to the topic "mutated".
| # | |||
|---|---|---|---|
| 1 | G4DSB | G-quadruplex DNA Structures and Genome Stability | 2015 |
| 2 | REMEMBER | Adaptive immunity in prokaryotes: how Bacteria do not forgive and do not forget their enemies | 2015 |
| 3 | EVOPRIMPOL | Artificial evolution of a novel multifunctional human polymerase | 2015 |
| 4 | Cancer-Drug-Screen | High-throughput drug screening for identifying personalized cancer treatments tailored to the particular mutations of the patient’s tumor | 2015 |
| 5 | Class II PI3K | Characterization of the signalling and physiological roles of the class II PI3Ks | 2016 |
| 6 | HAT-MOZ-sphere | Identification of genes and pathways regulated by the HAT activity of MOZ | 2015 |
| 7 | InteractomeMalMot | Interactome of surface proteins important for Plasmodium sporozoite gliding motility | 2015 |
| 8 | ParaplegiaERDros | Roles of spastic paraplegia proteins in organisation of axonal endoplasmic reticulum | 2016 |
| 9 | HepatoRiSK | A new tumor suppressor role for RSK2 in hepatocellular carcinoma | 2015 |
| 10 | ER_disease | Defining hormonal cross-talk and the role of mutations in estrogen receptor positive breast cancer | 2015 |
| 11 | FLYghtCaRe | Ca2+ feedback control of TRP/TRPL channels in Drosophila photoreceptors | 2015 |
| 12 | COMAL | COMAL:COhesin Mutations in Acute Leukemia: from modeling and mechanisms to novel therapeutics | 2015 |
| 13 | M-Imm | Novel etiology of autoimmune disorders: the role of acquired somatic mutations in lymphoid cells | 2015 |
| 14 | StemNicheOnWaveCrest | New therapies for myeloproliferative diseases based on multi-stage and -system analyses of the haematopoietic stem-cell niche | 2015 |
| 15 | AVATAR | Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment | 2015 |
| 16 | COMbAT | Commercialization of a novel tool for designing personalized nOvel MelAnoma Therapies | 2015 |
| 17 | SLACC | Supplying lung adenocarcinoma cell lines to the cancer research community. | 2015 |
| 18 | M6Abolic-RNA-duplex | Metabolic control of RNA-protein and RNA-RNA interactions in cellular transformation. | 2016 |
| 19 | EPILIPRO | Elucidating the role of Arid1a in adult liver | 2016 |
| 20 | SLIM | Synthetic Lethal Interactions with nucleophosMin 1 | 2016 |
| 21 | MECHANOCHECK | ATR-mediated mechanotransduction and connections with the actin cytoskeleton | 2016 |
| 22 | JHSIGNAL | Modulation of juvenile hormone signaling by receptor phosphorylation | 2017 |
| 23 | ZPR | The Pancreas Regulome: From causality to prediction of non-coding mutations in human pancreatic diseases | 2016 |
| 24 | Wnt and CRC | Therapeutic inhibition of the oncogenic Wnt/beta-catenin pathway in mismatch repair deficient hypermutant tumors | 2017 |
| 25 | Autonomous CLL-BCRs | Role of autonomous B cell receptor signalling and external antigen in the pathogenesis of chronic lymphocytic leukaemia (CLL) | 2016 |
| 26 | HOXA9 degradome | Deciphering the machinery involved in stability of the transcription factor HOXA9. | 2016 |
| 27 | SCUBA CANCERS | Finding the genetic causes of contagious metastases under the sea | 2017 |
| 28 | COLGENES | Defining novel mechanisms critical for colorectal tumourigenesis | 2017 |
| 29 | MuRChap | The mutation-buffering capacity of RNA chaperones | 2017 |
| 30 | SCALTIE | Single cell analysis of the lung tumour-immune ecosystem: Developing new tools for effective immunotherapy | 2017 |
| 31 | ResistEpist | Dissection of the mechanisms causing the epistasis between antibiotic resistance mutations in Escherichia coli | 2018 |
| 32 | TRIBBLES | Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma | 2018 |
| 33 | DNAmethAML | Investigation of aberrant DNA methylation in malignant haematopoiesis | 2018 |
| 34 | MUTAnTS | A microfluidic high throughput approach to helicase biophysics | 2018 |
| 35 | IC_IL_EC_2017 | Investigating the effects of immunogenic chemoradiation in shaping the immune landscape of esophageal cancers | 2018 |
| 36 | ContraNPM1AML | Dissecting to hit the therapeutic targets in nucleophosmin (NPM1)-mutated acute myeloid leukemia | 2017 |
| 37 | HEGEMONIC | HEpatocellular carcinoma GErmline MutatiONs ImpaCt (HEGEMONIC) | 2017 |
| 38 | MITOQUAD | Unveiling the mitochondrial role of DNA2, a human helicase-nuclease causing mtDNA deletion associated syndrome. | 2018 |
| 39 | DISMOD-HD | Direct reprogramming for HD Disease Modelling | 2017 |
| 40 | mtDNA-CURE | Treating mitochondrial disease caused by pathogenic mtDNA mutations | 2018 |
| 41 | TelMetab | Telomere metabolism in Genome Stability and Disease | 2017 |
| 42 | BURSTREG | Single-molecule visualization of transcription dynamics to understand regulatory mechanisms of transcriptional bursting and its effects on cellular fitness | 2018 |
| 43 | TREAT-NPM1-AML | Improving therapy of NPM1-mutated AML | 2017 |
| 44 | HIV B Cell Function | Understanding HIV-specific B cell function and viral immunogenicity | 2018 |
| 45 | TET2rec | Mechanisms of TET2 DNA demethylase recruitment to specific genomic regions | 2018 |
| 46 | TriboKey | Deformation Mechanisms are the Key to Understanding and Tayloring Tribological Behaviour | 2018 |
| 47 | UB-RASDisease | The ubiquitin system in RAS-driven disease | 2018 |
| 48 | PrunMut | Candidate mutation discovery in early-flowering mutants 'Rojo Pasión Precoz' and 'Bulida Precoz' | 2019 |
| 49 | SHINE | Self-Healthcare for breast cancer detection using an INtegrated paper-based Electrochemical device | 2019 |
| 50 | NEMoCuRe | Role of S-Nitrosylation of epigenetic modifiers in vascular regeneration | 2018 |
| 51 | HiMIN | Histone H3.3 oncogenic mutations: a role in genome instability through altered DNA repair and replication fork stability? | 2018 |
| 52 | ProMeta | Non-histone protein acetylation targets of KAT2A in AML | 2018 |
| 53 | BioMet | Selective Functionalization of Saturated Hydrocarbons | 2018 |
| 54 | RiZeSisT | Discovering susceptibility genes to Rhizoctonia solani in rice as breeding targets for sheath blight disease resistance | 2018 |
| 55 | AMR-TB | Theoretical and computational investigation of tuberculosis antimicrobial resistance development based on extensive experimental library of mycobacterium strains | 2019 |
| 56 | ONCOFUM | Integrating the tissue-specificity and chronology of hereditary renal cancer predisposition | 2019 |
| 57 | IMaP | Imaging tumor vessels as a marker for p53 mutation status in cancer | 2020 |
| 58 | REAP | Repair of DNA lesions induced by platinum drugs | 2019 |
| 59 | UMMATR | Uncovering molecular mechanisms of active transcriptional repression. | 2020 |
| 60 | iMIND | iPS-derived MIcroglia and Neuroinflammation in Dementia | 2020 |
| 61 | 2D-MES | Two Dimensional Molecular Electronics Spectroscopy for DNA/RNA Mutation Recognition | 2020 |
| 62 | PMLingAML | Using PML nuclear body biology to identify potential AML treatment targets | 2020 |
| 63 | THERAPE | Novel blood-brain barrier permeable CDNF-derived therapeutic peptides for the protection and regeneration of dopamine neurons | 2019 |
| 64 | LEPVORS | Identification and characterization of new drug resistance and host adaptation mechanisms in Mycobacterium leprae | 2019 |
| 65 | IBL-302 | Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer | 2019 |
| 66 | MetEpiC | P53-dependent Metabolic and Epigenetic Reprogramming in Carcinogenesis | 2020 |
| 67 | StreptoMANIAC | Cost and benefit of beta-lactam resistance in Streptococcus pneumoniae: interplay between the resistance determinants and the cell elongation/division components | 2019 |
| 68 | FUELING-TRANSPORT | Deciphering the Role of Huntingtin in Energy Supply for Axonal Transport in Health and Huntington’s Disease | 2020 |
| 69 | MOLEC ANTI-ARRHYT | Resilience and Trigger Factors in Cardiac Arrhythmia: Risk Stratification and Drug Design | 2020 |
| 70 | VIVA | Vaccine development against variable pathogens | 2020 |
| 71 | SILENT | Silent mutations in cancer | 2020 |
| 72 | BRCAstem | Monitoring cancer stem cell dynamics and therapeutic response in BRCA2-deficient breast tumour cells | 2020 |
| 73 | CRISPR-Locate | Linking sequence to function of long noncoding RNAs with CRISPR. | 2021 |
| 74 | ChRONAM-H | Chromatin Regulation Of Normal And Malignant Haematopoiesis | 2020 |
| 75 | RCC_Evo | Modelling the Predictability and Repeatability of Tumour Evolution in Clear Cell Renal Cell Cancer | 2020 |
| 76 | RASATaC | Regulating RAS Activity to Target RAS-Driven Cancers | 2020 |