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Automated mini-invasive surgical approach to the treatment of mitral insufficiency

Total Cost €


EC-Contrib. €






 MITrep project word cloud

Explore the words cloud of the MITrep project. It provides you a very rough idea of what is the project "MITrep" about.

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Project "MITrep" data sheet

The following table provides information about the project.


Organization address
postcode: 43120
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-12-01   to  2019-05-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CMI NOV FR (MONISTROL SUR LOIRE) coordinator 50˙000.00


 Project objective

Mitral valve insufficiency is a heart condition, where blood is abnormally leaking out of the mitral valve. This condition mainly afflicts the elderly patients: - 80% of patients aged 80 show moderate symptoms (chronic fatigue, shortness of breath, palpitations, racing heart rate) - 10% of patients above 75 with severe symptoms are at risk of a sudden death (stroke) within 5 years. - Prevalence will double by 2030. Mitral insufficiency is treated with open heart surgery (300,000 operations/year in the EU and the USA) followed by intensive care. But this operation is unbearable for fragile patients. Half of the patients above 75 are tagged inoperable because of their age. Less invasive repair surgeries have been tested (annuloplasty by transfemoral surgery) but lack efficiency and safety and require highly skilled surgeons (not available in each hospital). In this context, the company CMI’nov has developed MITrep, the first patented mini-invasive surgical device that automatically goes to the mitral valve with no trial and error to affix a leak-preventing ring on the valve. It uses the transapical approach. Once the ring is anchored, the mitral valve returns to normal activity. No heavy post-surgery effects are expected. No intensive care required.

MITrep can be used by any surgeons : no need to be a mitral valve specialist. It will allow to halve the operation time (from 5 hours to less than 2 hours), reduce hospitalization time to 3 days (vs 5-8 days with 2 days in ICU) and cost about three times less than open heart surgery (30k€ vs 80k€). It means a dramatic cost reduction for healthcare systems and a real improvement of the care of the elderly patient.

This project holds the ambition to build a new gold standard in valvuloplasty worldwide, starting with mitral repair and replicable to aortic and tricuspid valve repair. It is also a value driver for CMI’nov. The Phase 1 project will validate the feasibility of MITrep before scale-up and deployment.

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The information about "MITREP" are provided by the European Opendata Portal: CORDIS opendata.

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