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EvolMAX SIGNED

Molecular determinants of host adaptation in fungal-plant pathogens: origins and evolution of virulence effectors by genomic, phylogenetic and association mapping studies

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EvolMAX" data sheet

The following table provides information about the project.

Coordinator
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT 

Organization address
address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338
website: www.inra.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 196˙707 €
 EC max contribution 196˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) coordinator 196˙707.00

Map

 Project objective

The ability of pathogens to escape plant immune system recognition and host defenses is a significant driver of disease emergence. Small proteins secreted by fungal pathogens, named effectors, play a key role in the ability of pathogens to infect novel hosts. Fungal pathogens harbor large and highly diverse repertoires of effectors. This tremendous effector repertoire variability within and between species has hindered the characterization of effectors for their role in adaptation to novel hosts, which is limited to a tiny fraction of effectors. EvolMAX aims to lift this methodological barrier by focusing on one of the first large family of effectors discovered in fungi in order to identify the molecular processes underlying changes in virulence and adaptation to novel hosts. Building on the recent discovery of the MAX (Magnaporthe Avrs and ToxB) family of effectors in the multihost pathogen Magnaporthe oryzae, this project will jointly characterize and infer the evolutionary history of reasonably-sized sets of effectors. Using comparative genomics, population genomics, large-scale pathogenicity tests and genome-wide association mapping in host-specific M. oryzae lineages, EvolMAX will identify candidate loci involved in adaptation to novel hosts and raise understanding of the origins, diversification history of fungal effectors. The molecular processes underlying pathogen evolution and host adaptation are essential to design efficient and sustainable disease control strategies.

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The information about "EVOLMAX" are provided by the European Opendata Portal: CORDIS opendata.

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