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variaTECT SIGNED

A novel genetic assay for risk assessment of cognitive decline in Alzheimer’s Disease

Total Cost €

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EC-Contrib. €

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Partnership

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 variaTECT project word cloud

Explore the words cloud of the variaTECT project. It provides you a very rough idea of what is the project "variaTECT" about.

accurate    broad    nucleotide    stratify    figure    aging    46m    types    2030    130k    blood    strategy    positron    almost    dementia    save    disease    dysfunction    proprietary    diagnostic    snps    lumbar    double    variatect    population    innovation    snpfitr    emission    individuals    mark    85    clinical    provides    alzheimer    trials    solutions    genetic    10k    obtain    capacity    deployment    vitro    generate    detection    person    platform    pieces    tests    patient    primary    10m    revenues    saliva    disorder    tomography    pet    ivd    complete    snpfitrtm    multiple    ad    labs    puncture    fluid    brain    plan    living    people    initiated    plasma    drafted    triple    snp    processed    subjects    collected    supply    feasibility    polymorphism    device    progressively    fast    chain    cytox    amyloid    data    cerebrospinal    csf    2050    ce    market    accuracy    degeneration    dna    software    probability    leads    upgrade    extracted    healthcare    array    scans    single    risk    score    worldwide    unresolved    cognitive    beta    prevalent   

Project "variaTECT" data sheet

The following table provides information about the project.

Coordinator
CYTOX LIMITED 

Organization address
address: 53 FOUNTAIN STREET
city: MANCHESTER
postcode: M2 2AN
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.cytoxgroup.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2019-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CYTOX LIMITED UK (MANCHESTER) coordinator 50˙000.00

Map

 Project objective

Alzheimer’s Disease (AD) is the most prevalent cognitive disorder and progressively leads to complete brain dysfunction and degeneration. The number of people living with Alzheimer’s worldwide is now estimated at 46M, with this figure set to almost double by 2030 and more than triple by 2050 due to population aging. Current methods for early assessment of AD are based on detection of β-amyloid in the brain Positron Emission Tomography (PET) scans, blood plasma tests or in cerebrospinal fluid (CSF) (via lumbar puncture). However, these solutions present some unresolved issues for broad market deployment. Cytox has developed the variaTECT platform to stratify AD risk in individuals by using a fast, accurate, reliable and cost-effective way to generate specific genetic information. The variaTECT comprises a proprietary 130K single nucleotide polymorphism (SNP) variaTECT array and the proprietary SNPfitRTM software to analyse data generated from the array. DNA extracted from a patient’s blood or saliva sample is collected and analyzed on the variaTECT array. The primary genetic data are then processed by the SNPfitR software, which provides a risk score associated with the probability to develop AD. variaTECT has an 85% accuracy, it can save up to €10k person-year for the healthcare systems and it can generate new revenues (up to €10M) for genetic labs. During the feasibility assessment, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. During the second phase of innovation project, Cytox will upgrade the array design to increase the number of SNPs and the SNPfitR software to stratify subjects into different dementia types. Production capacity will be increased up to 100,000 pieces per year. Multiple clinical trials will be then initiated to obtain CE mark as In-Vitro Diagnostic (IVD) device.

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The information about "VARIATECT" are provided by the European Opendata Portal: CORDIS opendata.

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