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A novel genetic assay for risk assessment of cognitive decline in Alzheimer’s Disease

Total Cost €


EC-Contrib. €






 variaTECT project word cloud

Explore the words cloud of the variaTECT project. It provides you a very rough idea of what is the project "variaTECT" about.

pieces    mark    aging    chain    software    unresolved    polymorphism    positron    labs    probability    processed    snpfitrtm    tests    upgrade    emission    types    figure    tomography    worldwide    ivd    primary    blood    leads    snps    2050    puncture    trials    vitro    variatect    revenues    strategy    amyloid    population    cognitive    pet    genetic    accurate    85    saliva    deployment    progressively    46m    plan    double    nucleotide    dementia    data    degeneration    provides    extracted    cytox    beta    market    clinical    alzheimer    csf    snpfitr    2030    subjects    disorder    obtain    scans    device    fluid    save    innovation    dysfunction    broad    prevalent    array    snp    supply    multiple    plasma    generate    accuracy    feasibility    stratify    brain    complete    disease    person    10k    patient    130k    detection    living    fast    individuals    score    platform    solutions    healthcare    dna    proprietary    risk    single    initiated    ce    people    cerebrospinal    diagnostic    10m    capacity    almost    drafted    ad    collected    lumbar    triple   

Project "variaTECT" data sheet

The following table provides information about the project.


Organization address
postcode: M2 2AN
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2019-05-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CYTOX LIMITED UK (MANCHESTER) coordinator 50˙000.00


 Project objective

Alzheimer’s Disease (AD) is the most prevalent cognitive disorder and progressively leads to complete brain dysfunction and degeneration. The number of people living with Alzheimer’s worldwide is now estimated at 46M, with this figure set to almost double by 2030 and more than triple by 2050 due to population aging. Current methods for early assessment of AD are based on detection of β-amyloid in the brain Positron Emission Tomography (PET) scans, blood plasma tests or in cerebrospinal fluid (CSF) (via lumbar puncture). However, these solutions present some unresolved issues for broad market deployment. Cytox has developed the variaTECT platform to stratify AD risk in individuals by using a fast, accurate, reliable and cost-effective way to generate specific genetic information. The variaTECT comprises a proprietary 130K single nucleotide polymorphism (SNP) variaTECT array and the proprietary SNPfitRTM software to analyse data generated from the array. DNA extracted from a patient’s blood or saliva sample is collected and analyzed on the variaTECT array. The primary genetic data are then processed by the SNPfitR software, which provides a risk score associated with the probability to develop AD. variaTECT has an 85% accuracy, it can save up to €10k person-year for the healthcare systems and it can generate new revenues (up to €10M) for genetic labs. During the feasibility assessment, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. During the second phase of innovation project, Cytox will upgrade the array design to increase the number of SNPs and the SNPfitR software to stratify subjects into different dementia types. Production capacity will be increased up to 100,000 pieces per year. Multiple clinical trials will be then initiated to obtain CE mark as In-Vitro Diagnostic (IVD) device.

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The information about "VARIATECT" are provided by the European Opendata Portal: CORDIS opendata.

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