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STRICT SIGNED

SN: The first blood biomarker to accurately STratify mortality Risk In patients with Cardiac arrhyTmia

Total Cost €

EC-Contrib. €

Partnership

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STRICT project word cloud

Explore the words cloud of the STRICT project. It provides you a very rough idea of what is the project "STRICT" about.

diagnosis sudden competitive physical unknowingly mortality implantable shown ejection acquiring device skills detect secretoneurin defibrillator quality victims sme positioning caused ecg left data sn normal 3b health burden death cardiologists lives advantage biomarker least maturation levels expertise 67 worldwide icds market icd patients vitro correlation cardioverter difficult decision global globally patient saving alone eligible cardiovascular stratify arrhythmias biomedical 20k 35 cardinor risk diagnostic 25 survival 51 blood ventricular echocardiogram overtreatment pinpoint associate scd cvd disease company ivd status linked assurance ask house coming killer recruit cardiac accurate exams biomarkers activated never ventricle regime surgery lt patented arrythmia boost trl8 reducing lvef innovation

Project "STRICT" data sheet

The following table provides information about the project.

Coordinator	CARDINOR AS Organization address address: GAUSTADALLEEN 21 city: OSLO postcode: 349 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Norway [NO]
Total cost	119˙805 €
EC max contribution	119˙805 € (100%)
Programme	1. H2020-EU.2.3.2.2. (Enhancing the innovation capacity of SMEs)
Code Call	H2020-INNOSUP-2019-02
Funding Scheme	CSA
Starting year	2019
Duration (year-month-day)	from 2019-12-15 to 2020-12-14

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CARDINOR AS CARDINOR AS Organization address address: GAUSTADALLEEN 21 city: OSLO postcode: 349 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	coordinator	119˙805.00

Map

Project objective

Cardiovascular disease (CVD) is the no. 1 killer worldwide. 25% of all CVD mortality is caused by ventricular arrhythmias that lead to sudden cardiac death (SCD). The diagnosis of arrhythmias is difficult but crucial for accurate decision-making and patient survival. To assess the patient’s status, cardiologists currently ask: physical exams, some cardiac biomarkers data, an ECG (which may detect an arrythmia) and an echocardiogram to measure the blood ejection from the left ventricle (LVEF), since there is a correlation between LVEF and risk of ventricular arrhythmias. If LVEF is < 35%, the patient is eligible for implantable cardioverter-defibrillator (ICD) surgery, which costs at least 20K€. Still, around 51 % of victims of SCD have normal LVEF. In addition, 67% of all implemented ICDs are never activated because those patients were (unknowingly) at low-risk for arrhythmias, which represents a 1.3B€ overtreatment cost / year in the EU alone. CardiNor is bringing to market a new in vitro diagnostic (IVD) test to measure blood levels of Secretoneurin (SN), a globally patented biomarker and the only one shown to be specifically linked to ventricular arrhythmias. With SN data, cardiologists will be able to stratify patients according to their risk as well as to pinpoint high-risk patients not identified by the current diagnostic regime, thus reducing health burden costs and saving lives. CardiNor needs the SME Innovation Associate Programme to boost R&D activities within test maturation and effectively take it to TRL8. Currently, we do not have in-house expertise in biomedical device development or quality assurance. Therefore, we are looking to recruit an Innovation Associate. Acquiring these skills is important for CardiNor to maintain competitive advantage over coming years, positioning our company to high growth in the global CVD biomarkers market.

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The information about "STRICT" are provided by the European Opendata Portal: CORDIS opendata.