Opendata, web and dolomites

Magicbullet Reloaded SIGNED

Small-Molecule Drug Conjugates for Targeted Delivery in Tumor Therapy

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 Magicbullet Reloaded project word cloud

Explore the words cloud of the Magicbullet Reloaded project. It provides you a very rough idea of what is the project "Magicbullet Reloaded" about.

expert    peptide    1908    competences    paul    acquired    magicbullet    grant    academia    cells    interdisciplinary    etn    kills    refers    scientific    array    premature    had    direction    death    industry    cancer    substantially    esrs    despite    reloaded    environment    broad    brings    agent    antigens    recruited    faceted    cell    efforts    organism    disease    continuing    biology    idea    chemistry    molecule    complementarity    outstanding    small    tissue    implication    physiology    title    treatments    2018    discovery    ehrlich    medicinal    overcome    resistance    pipeline    biochemistry    investigation    tumor    drugs    compound    efficient    builds    ideal    antitumor    selectively    bold    toxin    laureate    pdcs    drug    organic    immuno    nobel    642004    expanded    special    versa    immune    expand    perfectly    basis    pharmacology    pharmacokinetic    successful    conjugates    vice    therapy    consequence    worldwide    therapeutic    made    delivered    vision    bullet    magic    causing    2015    exposed    synthesize    selectivity    stimulate    smdcs   

Project "Magicbullet Reloaded" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAET BIELEFELD 

Organization address
address: UNIVERSITAETSSTRASSE 25
city: BIELEFELD
postcode: 33615
website: www.uni-bielefeld.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 3˙915˙902 €
 EC max contribution 3˙915˙902 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAET BIELEFELD DE (BIELEFELD) coordinator 252˙788.00
2    UNIVERSITY OF NEWCASTLE UPON TYNE UK (NEWCASTLE UPON TYNE) participant 303˙172.00
3    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 281˙276.00
4    PHILOCHEM AG CH (OTELFINGEN) participant 281˙276.00
5    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) participant 280˙805.00
6    EXIRIS SRL IT (ROMA) participant 261˙499.00
7    TAKIS SRL IT (ROMA) participant 261˙499.00
8    UNIVERSITA DEGLI STUDI DELL'INSUBRIA IT (VARESE) participant 261˙499.00
9    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 261˙499.00
10    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 252˙788.00
11    HEIDELBERG PHARMA RESEARCH GMBH DE (LADENBURG) participant 252˙788.00
12    TECHNISCHE UNIVERSITAT DARMSTADT DE (DARMSTADT) participant 252˙788.00
13    UNIVERSITAET ZU KOELN DE (KOELN) participant 252˙788.00
14    EOTVOS LORAND TUDOMANYEGYETEM HU (BUDAPEST) participant 229˙715.00
15    Orszagos Onkologiai Intezet HU (Budapest) participant 229˙715.00

Map

 Project objective

'Despite the continuing development of new and more efficient treatments, cancer remains the second cause of premature death worldwide. Multi-faceted interdisciplinary research efforts in industry and academia on different aspects of cancer have provided a knowledge basis for the development of novel therapeutic approaches. Paul Ehrlich, Nobel laureate in Physiology of 1908, had the early vision that a compound could be made to selectively target a disease-causing organism or tumor. A toxin for the particular tissue could be delivered by an agent of selectivity. Such an ideal therapeutic agent would be a 'magic bullet' that only kills the target cells. This ETN initiative with the title Magicbullet::reloaded refers to Ehrlich’s bold idea and builds on the previous experience of the highly successful ETN MAGICBULLET (2015-2018, grant agreement No. 642004). As a consequence of the outstanding results, the ETN Magicbullet::reloaded will expand the field of investigation from peptide-drug conjugates (PDCs) to small molecule-drug conjugates (SMDCs) with a special focus on drugs capable to stimulate tumor immune responses and overcome resistance to immuno-therapy. The consortium has been substantially expanded to perfectly address the needs of the new research direction. The planned ETN will design and synthesize an array of SMDCs (including PDCs), also targeting less investigated tumor antigens, investigate their pharmacokinetic behaviour, their implication on the immune system, as well as their tumor selectivity and antitumor activity. The consortium brings together interdisciplinary expert knowledge in Organic Chemistry, Peptide Chemistry, Medicinal Chemistry, Drug Discovery, Biochemistry, Pharmacology and Cell Biology. This high complementarity is required for the different scientific tasks in the development pipeline. Vice versa, the recruited ESRs will be exposed to a challenging research environment leading to a broad range of scientific competences to be acquired.'

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MAGICBULLET RELOADED" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MAGICBULLET RELOADED" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.1.)

GREAT (2019)

Grating Reflectors Enabled laser Applications and Training

Read More  

GMOS-Train (2020)

Global Mercury Observation and Training Network in Support to the Minamata Convention

Read More  

LIVE-I (2020)

Lightening and Innovating transmission for improving Vehicle: Environmental Impacts

Read More