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DECODE SIGNED

reDucing the health and Economic COst of Diagnostic uncErtainty: launch and randomized control trial of the first validated bacterial versus viral test

Total Cost €

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EC-Contrib. €

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Partnership

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 DECODE project word cloud

Explore the words cloud of the DECODE project. It provides you a very rough idea of what is the project "DECODE" about.

complete    superiority    pioneering    settings    leads    risk    trial    dach    outcomes    diagnostics    patients    gap    key    routinely    biomarkers    children    routine    inferior    demonstrated    immune    healthcare    poc    data    500    conduct    commercially    viral    actionable    initiate    share    multicentre    enrolling    primary    fight    capillary    elevated    memed    release    solution    reduces    instances    antimicrobial    clinician    bv    externally    clinically    platform    hospitalization    validated    clinical    amr    diagnostic    constraints    problem    indistinguishable    15    threats    applicability    utility    workflow    market    tool    health    body    economic    validation    efforts    reducing    suspected    burden    broad    global    randomized    gaps    avoidable    clinicians    expand    cleared    samples    rct    distinguishing    decode    decodes    patient    trade    world    blood    minutes    gather    thousands    care    suitable    infection    bacterial    misuse    concurrently    double    resistance    decide    confidence    regulatory    compatible    infections    runs    inappropriate    blind    serum    acute   

Project "DECODE" data sheet

The following table provides information about the project.

Coordinator		 MEMED DIAGNOSTICS LTD 

Organization address
address: NAHUM HETH STREET 5
city: TIRAT CARMEL
postcode: 39120
website: www.me-med.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Israel [IL]
 Total cost 3˙571˙427 €
 EC max contribution 2˙499˙999 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MEMED DIAGNOSTICS LTD IL (TIRAT CARMEL) coordinator 2˙499˙999.00

Map

 Project objective

Problem: Clinicians routinely face diagnostic uncertainty because acute infections are often clinically indistinguishable and today’s diagnostics have constraints. This uncertainty leads to inappropriate patient management, including antimicrobial misuse and avoidable hospitalization. The associated health economic burden are inferior patient outcomes, elevated costs, and antimicrobial resistance (AMR), one of the top 10 threats to global health. Potential solution: In many instances, the clinician only needs to know with confidence if the infection is bacterial or viral to decide how to manage a patient suspected to have an acute infection. We have developed and validated MeMed BV™ - a pioneering test for distinguishing between bacterial and viral infections that decodes the body’s immune response to infection. BV™ has been both double-blind and externally validated in clinical studies enrolling thousands of patients and demonstrated superiority to biomarkers in routine use. Concurrently, we have developed Key™, an easy-to-use POC platform that runs BV™ in 15 minutes. Gap: Broad impact of BV™ and market share require high-risk efforts to address the following major gaps: 1. Real world evidence of usage and impact on workflow. 2. Validation of clinical utility in a randomized control trial (RCT). 3. Expand applicability to primary care settings. Proposed objectives: 1. To initiate market release in DACH and gather real world data. 2. To conduct a multicentre RCT enrolling 500 children. 3. Complete development of BV™ compatible with capillary blood. Impact: DECODE will take BV™ on Key™ from a test regulatory cleared for use to one that is available commercially and adopted in routine care, has validated clinical utility and is suitable for both serum and capillary blood samples. By providing an actionable tool that reduces diagnostic uncertainty, this project will improve patient outcomes while reducing healthcare costs and help fight AMR.

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The information about "DECODE" are provided by the European Opendata Portal: CORDIS opendata.

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