Explore the words cloud of the FI4P project. It provides you a very rough idea of what is the project "FI4P" about.
The following table provides information about the project.
UNIVERSITE DE LIEGE
|Coordinator Country||Belgium [BE]|
|Total cost||166˙320 €|
|EC max contribution||166˙320 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2020-03-16 to 2022-03-15|
Take a look of project's partnership.
The demand for sustainable methods to build chemical bonds has led to the rise of catalytic reactions, especially using abundant and benign metals. In this context, iron has emerged as a powerful catalyst to mediate various transformations including cross-couplings between (pseudo)halide electrophilic partners and organometallic nucleophiles, usually Grignard reagents.
We aim to develop a modular and versatile Flow-enabled Iron-catalysed cross-coupling protocol for Pharmaceutical applications (FI4P), leveraging the unique properties of flow chemistry to implement cross-couplings between organolithium derivatives and electrophiles. Building on the significant expertise of the academic host in this field, we will seek to harness flow technology to exert spatiotemporal control over reactive intermediates, thus ensuring the functionalisation of halide precursors with reactive lithium organyls generated in situ. The particularly high reaction rates observed in iron-catalysed cross-couplings will allow the incorporation of valuable functional groups usually incompatible with organolithium derivatives.
This approach will deliver a sustainable method to assemble relevant molecular scaffolds of interest to the pharmaceutical industry. With the involvement of NovAliX, an industrial partner specialised in transferring academic innovations into industrial processes, we will eventually apply our synthetic protocol to the large-scale manufacture of valuable APIs and the generation of a small collection of molecules designed to complement our existing library for Fragment Based Drug Design.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "FI4P" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "FI4P" are provided by the European Opendata Portal: CORDIS opendata.
Mathematics AnalogiesRead More
Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and IconographyRead More
Multi-color and single-molecule fluorescence imaging of intraflagellar transport in the phasmid chemosensory cilia of C. ElegansRead More