EUROHYP-1
"European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke"
| Coordinatore | UNIVERSITATSKLINIKUM ERLANGEN
Organization address
address: Maximiliansplatz 2 contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Sito del progetto | http://www.eurohyp1.eu/ |
| Totale costo | 14˙955˙344 € |
| EC contributo | 10˙941˙665 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-two-stage |
| Funding Scheme | CP-IP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-02-01 - 2017-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITATSKLINIKUM ERLANGEN
Organization address
address: Maximiliansplatz 2 contact info |
DE (ERLANGEN) | coordinator | 1˙822˙215.20 |
| 2 |
THE UNIVERSITY OF EDINBURGH
Organization address
address: OLD COLLEGE, SOUTH BRIDGE contact info |
UK (EDINBURGH) | participant | 1˙005˙203.00 |
| 3 |
REGION HOVEDSTADEN
Organization address
address: KONGENS VAENGE 2 contact info |
DK (HILLEROD) | participant | 787˙792.00 |
| 4 |
SKANE LANS LANDSTING
Organization address
city: KRISTIANSTAD contact info |
SE (KRISTIANSTAD) | participant | 737˙699.00 |
| 5 |
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA
Organization address
address: Piazzale Aldo Moro 5 contact info |
IT (ROMA) | participant | 682˙390.00 |
| 6 |
INSTITUT CATALA DE LA SALUT
Organization address
address: GRAN VIA DE LES CORTS CATALANES 587 contact info |
ES (BARCELONA) | participant | 655˙474.00 |
| 7 |
UNIVERSITY OF GLASGOW
Organization address
address: University Avenue contact info |
UK (GLASGOW) | participant | 481˙939.40 |
| 8 |
GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG GAB O
Organization address
address: Oskar-von-Miller-Ring 29 contact info |
DE (MUENCHEN) | participant | 425˙000.00 |
| 9 |
CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE
Organization address
address: AVENUE OSCAR LAMBRET 2 contact info |
FR (LILLE) | participant | 403˙726.00 |
| 10 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Organization address
address: 101 Rue de Tolbiac contact info |
FR (PARIS) | participant | 401˙565.00 |
| 11 |
UNIVERSITAETSKLINIKUM HEIDELBERG
Organization address
address: IM NEUENHEIMER FELD 672 contact info |
DE (HEIDELBERG) | participant | 331˙789.60 |
| 12 |
EUROPEAN STROKE RESEARCH NETWORK FOR HYPOTHERMIA ASBL
Organization address
address: SQUARE DE MEEUS 38/40 contact info |
BE (BRUXELLES) | participant | 326˙040.00 |
| 13 |
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Organization address
address: HEIDELBERGLAAN 100 contact info |
NL (UTRECHT) | participant | 322˙934.40 |
| 14 |
THE UNIVERSITY OF NOTTINGHAM
Organization address
address: University Park contact info |
UK (NOTTINGHAM) | participant | 296˙140.00 |
| 15 |
FUNDACIO INSTITUT DE RECERCA DE L'HOSPITAL UNIVERSITARI VALL D'HEBRON
Organization address
address: Passeig Vall d'Hebron contact info |
ES (BARCELONA) | participant | 257˙396.00 |
| 16 |
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Organization address
address: Chariteplatz 1 contact info |
DE (BERLIN) | participant | 247˙683.00 |
| 17 |
VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMA
Organization address
address: KIINAMYLLYNKATU 4-8 contact info |
FI (TURKU) | participant | 197˙943.00 |
| 18 |
TECHNISCHE UNIVERSITAET DRESDEN
Organization address
address: HELMHOLTZSTRASSE 10 contact info |
DE (DRESDEN) | participant | 196˙004.00 |
| 19 |
INSTYTUT PSYCHIATRII I NEUROLOGII
Organization address
address: ULICA SOBIESKIEGO 9 contact info |
PL (WARSZAWA) | participant | 160˙396.00 |
| 20 |
DEMOCRITUS UNIVERSITY OF THRACE
Organization address
address: PANEPISTIMIOUPOLI contact info |
EL (KOMOTINI) | participant | 126˙929.00 |
| 21 |
EMCOOLS - MEDICAL COOLING SYSTEMS AG
Organization address
address: BRUCKNERSTRASSE 6/7 A contact info |
AT (WIEN) | participant | 120˙093.00 |
| 22 |
MEDIZINISCHE UNIVERSITAET INNSBRUCK
Organization address
address: Christoph-Probst Platz 1 contact info |
AT (INNSBRUCK) | participant | 119˙200.00 |
| 23 |
UNIVERSITAET LEIPZIG
Organization address
address: RITTERSTRASSE 26 contact info |
DE (LEIPZIG) | participant | 116˙835.00 |
| 24 |
HACETTEPE UNIVERSITESI
Organization address
address: HACETTEPE UNIVERSITESI BEYTEPE KAMPUSU REKTORLUK BINASI contact info |
TR (CANKAYA ANKARA) | participant | 112˙053.00 |
| 25 |
ALGEMEEN ZIEKENHUIS SINT-JAN BRUGGE-OOSTENDE AUTONOME VERZORGINSINSTELLING
Organization address
address: Ruddershove 10 contact info |
BE (Brugge) | participant | 101˙706.00 |
| 26 |
VIESOJI ISTAIGA VILNIAUS UNIVERSITETO LIGONINES SANTARISKIU KLINIKOS
Organization address
address: SANTARISKIU G 2 contact info |
LT (VILNIUS) | participant | 97˙353.50 |
| 27 |
ELVIDO MEDICAL TECHNOLOGY SRL
Organization address
address: VIALE DELLA VITTORIA 214 contact info |
IT (VITTORIO VENETO TV) | participant | 90˙300.00 |
| 28 |
UNIVERSITE PARIS XII VAL DE MARNE
Organization address
address: AVENUE DU GENERAL DE GAULLE 61 contact info |
FR (CRETEIL) | participant | 71˙580.00 |
| 29 |
STROKE ALLIANCE FOR EUROPE
Organization address
address: RUE WASHINGTON 40 contact info |
BE (BRUSSELS) | participant | 64˙600.00 |
| 30 |
QUICK COOL AB
Organization address
address: SCHEELEVAGEN BETA 6 IDEON SCIENCE PARK 17 contact info |
SE (LUND) | participant | 45˙002.00 |
| 31 |
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Organization address
address: Via Giuseppe La Masa 19 contact info |
IT (MILANO) | participant | 38˙400.00 |
| 32 |
FLOWLAB PROYECTOS DE INNOVACION SL
Organization address
address: AVENIDA DE LA TORREBLANCA 57 1 A 4 ESADECREAPOLIS contact info |
ES (SANT CUGAT DEL VALLES) | participant | 35˙101.00 |
| 33 |
ELECTROPHORETICS LTD
Organization address
address: COVEHAM HOUSE DOWNSIDE BRIDGE ROAD contact info |
UK (COBHAM) | participant | 31˙770.00 |
| 34 |
Randox Clinics Limited
Organization address
address: Diamond Road 34 contact info |
UK (Crumlin) | participant | 30˙602.00 |
| 35 |
TARTU ULIKOOL
Organization address
address: ULIKOOLI 18 contact info |
EE (TARTU) | participant | 811.24 |
| 36 |
NATIONAL STROKE RESEARCH INSTITUTE
Organization address
address: BURGUNDY ST 245 contact info |
AU (HEIDELBERG) | participant | 0.00 |
Mappa
Word cloud
Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.
Obiettivo del progetto (Objective)
'The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke. Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so its social and economic burden will grow with the ageing of the European population. Current treatment options for the 80 to 85% of all strokes due to cerebral ischaemia - around. 900,000 events in Europe every year, or one every 40 seconds - are extremely limited. Systematic review of experimental studies suggests that hypothermia is the most promising intervention identified to date. Therapeutic cooling is effective in reducing ischaemic brain injury following cardiac arrest, and hypothermia is therefore considered by experts the most promising treatment for patients with acute ischaemic stroke, next to reperfusion strategies. The EuroHYP-1 trial is a pan-European, open, randomised, phase III clinical trial which will assess the benefit or harm of therapeutic cooling in 1500 awake adult patients with acute ischaemic stroke. In addition to efficacy and safety, the economic impact of therapeutic hypothermia will be assessed, along with several sub-studies involving imaging, ultrasound, and biomarker methods. The investigators involved in the EuroHYP-1 consortium are leading European experts in statistical design and analysis, therapeutic hypothermia, imaging, health economics, ultrasound, biomarkers, and trial execution (implementation and monitoring). Moreover – in addition to these academic experts the consortium also involves European patient and family advocacy groups and small and medium-size enterprises, and the joint endeavours of this extended team will ensure the successful enrolment of patients at eighty hospitals across 25 countries in Europe.'
Introduzione (Teaser)
Stroke is one of the leading causes of death and disability with limited treatment options even in developed countries. Broad assessment of new approaches is necessary for better management and rehabilitation of stroke patients.