RADAR

Rationally Designed Aquatic Receptors integrated in label-free biosensor platforms for remote surveillance of toxins and pollutants

Coordinatore	CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT    more  Organization address address: RUE JAQUET DROZ 1 city: NEUCHATEL postcode: 2007 contact info Titolo: Prof. Nome: Peter Cognome: Seitz Email: send email Telefono: +41 81 307 8101 Fax: +41 81 307 8100
Nazionalità Coordinatore	Switzerland [CH]
Totale costo	3˙896˙412 €
EC contributo	2˙926˙127 €
Programma	FP7-KBBE Specific Programme "Cooperation": Food, Agriculture and Biotechnology
Code Call	FP7-KBBE-2010-4
Funding Scheme	CP-FP
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-01-01   -   2014-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT  Organization address address: RUE JAQUET DROZ 1 city: NEUCHATEL postcode: 2007 contact info Titolo: Prof. Nome: Peter Cognome: Seitz Email: send email Telefono: +41 81 307 8101 Fax: +41 81 307 8100	CH (NEUCHATEL)	coordinator	952˙267.00
2	JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION  Organization address address: Rue de la Loi 200 city: BRUSSELS postcode: 1049 contact info Titolo: Dr. Nome: Iain Cognome: Formosa Email: send email Telefono: +39 0332 786091 Fax: +39 0332 785730	BE (BRUSSELS)	participant	802˙650.00
3	STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK  Organization address address: Costerweg 50 city: WAGENINGEN postcode: 6701BH contact info Titolo: Mr. Nome: Jelte Cognome: Zeilstra Email: send email Telefono: +31 317 480258 Fax: +31 317 417717	NL (WAGENINGEN)	participant	313˙662.00
4	FONDAZIONE PER L'ISTITUTO DI RICERC A IN BIOMEDICINA  Organization address address: Via Vincenzo Vela 6 city: BELLINZONA postcode: 6500 contact info Titolo: Prof. Nome: Giorgio Cognome: Noseda Email: send email Telefono: +41 91 820 0309 Fax: +41 91 820 0302	CH (BELLINZONA)	participant	284˙387.00
5	OPTICS BALZERS AG  Organization address address: NEUGRUT 35 city: BALZERS postcode: 9496 contact info Titolo: Mr. Nome: Alex Cognome: Vogt Email: send email Telefono: +423 388 9207 Fax: +423 388 9391	LI (BALZERS)	participant	277˙210.00
6	Elysium Projects Limited  Organization address address: Deiniol Road Unit 2, Mentec city: BANGOR postcode: LL57 2UP contact info Titolo: Mr. Nome: John Cognome: Bostock Email: send email Telefono: +44 1248 361501 Fax: +44 1248361501	UK (BANGOR)	participant	215˙250.00
7	NACIONALNI INSTITUT ZA BIOLOGIJO  Organization address address: VECNA POT 111 city: LJUBLJANA postcode: 1000 contact info Titolo: Mr. Nome: Potocnik Cognome: Franc Email: send email Telefono: +386 59232704 Fax: +386 12412980	SI (LJUBLJANA)	participant	80˙701.00

Mappa

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 Obiettivo del progetto (Objective)

RADAR is a 7-member consortium that aims to develop a robust, sensitive, and versatile label-free, biosensor platform for spot measurements and on-line monitoring of toxins and pollutants in food production processes and in the aquatic environment. Specificity towards chemical pollutants and toxins is achieved by using recombinant receptors (namely the estrogen receptor and the aryl hydrocarbon receptor) whose amino acid sequences have been rationally designed based on genomic and functional information from aquatic organisms. Sensitivity of the biosensor is increased by the unique combination of isotachophoretic pre-concentration step, and surface nanostructuring & chemical modification. The integration of the label-free detection sensors with an on-line automated sample handling and a wireless communication system will yield a best-in-class biosensor platform for robust, specific and sensitive detection of EDCs and PAHs in difficult operating conditions. To validate the RADAR biosensor the consortium will test the biosensors in fresh and marine water, in fish farms, and in food products such as fish, fruit juices, and milk. Through their contacts in these industries, the partners will evaluate the performance of the biosensors in such environments, analyzing a representative number of samples and reporting on the stability, ruggedness and accuracy of the sensors used under laboratory and real test conditions.

This project is expected to have a high economic impact, since our cost-effective sensor could find a worldwide distribution in most food production and water testing lines as supported by Agilent Technologies Inc.

Introduzione (Teaser)

Contaminants in food and water supplies are increasingly prevalent, disrupting the endocrine system and even causing cancer. A highly sensitive portable platform exploiting receptors of the pollutants in aquatic organisms will have major impact.