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One4Two SIGNED

All-in-one genetic test for fast and accurate diagnosis of the causes of infertility

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 One4Two project word cloud

Explore the words cloud of the One4Two project. It provides you a very rough idea of what is the project "One4Two" about.

psychological    origin    handful    therapies    pregnancy    certifications    cumbersome    preventing    diagnostic    sequencing    blood    caused    causes    treat    kronosdna    citizens    strategy    software    protocol    laboratories    parent    adding    times    cover    suitable    upscaling    simplify    affordable    mutations    tests    report    dna    couple    ground    25    price    infertility    desire    scores    genetic    business    lack    negatively    35    inherited    provides    consolidating    million    fertility    prepare    diseases    transmission    complete    infertile    service    fragmented    lab    model    reduce    couples    impacts    complicates    pricing    marketing    distress    uncomprehensive    panel    generation    diagnosis    gynecologists    poised    effectiveness    time    probability    commercialization    proprietary    first    batteries    gynecologist    days    prescribed    investigation    workload    fulfilling    optimized    one4two    reproductive    reagents    linked    disorder   

Project "One4Two" data sheet

The following table provides information about the project.

Coordinator
KRONOSDNA S.R.L. 

Organization address
address: VIA LOGGIA DEI PISANI 25
city: NAPOLI
postcode: 80133
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://kronosdna.blog/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KRONOSDNA S.R.L. IT (NAPOLI) coordinator 50˙000.00

Map

 Project objective

Infertility is a disorder of the reproductive system which affects 25 million citizens in Europe, preventing them from fulfilling their desire to become a parent. To identify its causes, genetic testing is prescribed to around 35% of the couples under diagnosis, since several factors related to infertility have a genetic origin. However, the effectiveness of infertility genetic analysis and the whole diagnosis process are affected by several issues: an uncomprehensive approach to fertility genetic test, with just a handful of genetic diseases being investigated, each through a dedicated test; a fragmented and cumbersome genetic investigation process that negatively impacts on the couple, adding to the psychological distress caused by infertility, with several batteries of tests often in different laboratories, long diagnosis times and high costs; the lack of a specific genetic testing protocol and diagnosis report for infertility, which increases the workload for laboratories and complicates the diagnosis by gynecologists. KronosDNA has developed One4Two, the first integrated system that provides a comprehensive diagnostic service for the infertile couple, able to cover the whole diagnostic path from lab analysis (through a panel of reagents to analyse DNA through Next Generation Sequencing) to the diagnostic report (by means of a proprietary analysis software). One4Two, with just one blood sample, in 5 days and at an affordable price, provides a complete report on the mutations linked to infertility, probability scores for the transmission of inherited diseases, and the most suitable ART therapies to treat infertility. This is poised to reduce analysis workload, simplify diagnosis by the gynecologist and reduce time to pregnancy. During Phase 1 project, the system will be optimized with end-users to prepare the ground for the required certifications, upscaling and commercialization, by also consolidating the business model, the marketing strategy and the pricing.

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The information about "ONE4TWO" are provided by the European Opendata Portal: CORDIS opendata.

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