Explore the words cloud of the NIBSAD project. It provides you a very rough idea of what is the project "NIBSAD" about.
The following table provides information about the project.
PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI
|Coordinator Country||Italy [IT]|
|Total cost||180˙277 €|
|EC max contribution||180˙277 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2015-11-01 to 2017-10-31|
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|1||PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI||IT (BRESCIA)||coordinator||180˙277.00|
Ageing of the European population is increasing prevalence of age-related diseases such as Alzheimer’s disease (AD). AD is considered a public health priority due to socio-economic costs and limited efficacy of current pharmacological treatments. Co-registration of electroencephalogram (EEG) and transcranial magnetic stimulation (TMS) is a novelty, non-expensive and non-invasive approach to obtain surrogate markers of cognitive decline. Moreover, repetitive TMS (rTMS) is considered a promising tool to induce neuroplasticity and improve cognitive functions. The main objective of this research is providing markers of brain activity, reactivity, connectivity and plasticity related with healthy and pathological ageing (i.e., early AD). Thus, samples of healthy young, healthy elderly and AD patients will perform a behavioural task (to study visuospatial attention and cognitive control processes) while carrying out EEG recording and online EEG/TMS co-registration. Correlates of brain activity (event-related brain potentials), reactivity (amplitude of TMS evoked potential -TEP) and connectivity (TEP topography, coherence, synchronization, and graph theoretical analysis of complex networks) will be obtained before and after of delivering offline rTMS. It will allow studying differences in cortical responses induced by rTMS on each group of participants, which will provide correlates and biomarkers of brain plasticity related with age and AD. These biomarkers will allow the identification of individuals at early stages of AD and evaluating efficacy of novel TMS treatments. Importantly, identification of rTMS parameters responsible to induce neural plasticity and improve cognitive functions will contribute to develop rehabilitation protocols for AD patients.
|year||authors and title||journal||last update|
JesÃºs CespÃ³n, Carlo Miniussi, Maria Concetta Pellicciari
Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
published pages: , ISSN: 1568-1637, DOI:
|Ageing Research Reviews||2019-06-17|
JesÃºs CespÃ³n, Maria Concetta Pellicciari, Carlo Miniussi
Brain activity, excitability, and impaired performance in young and elderly subjects after rTMS
published pages: , ISSN: 0197-4580, DOI:
|Neurobiology of Aging||2019-06-17|
JesÃºs CespÃ³n, Claudia Rodella, Paolo M. Rossini, Carlo Miniussi, Maria C. Pellicciari
Anodal Transcranial Direct Current Stimulation Promotes Frontal Compensatory Mechanisms in Healthy Elderly Subjects
published pages: , ISSN: 1663-4365, DOI: 10.3389/fnagi.2017.00420
|Frontiers in Aging Neuroscience 9||2019-06-17|
JesÃºs CespÃ³n, Santiago Galdo-Ãlvarez, Fernando DÃaz
Cognitive control activity is modulated by the magnitude of interference and pre-activation of monitoring mechanisms
published pages: 39595, ISSN: 2045-2322, DOI: 10.1038/srep39595
|Scientific Reports 6||2019-06-17|
JesÃºs CespÃ³n, Claudia Rodella, Carlo Miniussi, Maria Concetta Pellicciari
Promotion of frontal compensatory mechanisms in healthy elderly and Alzheimerâ€™s disease patients involves the use of different tDCS polarity
published pages: , ISSN: 1388-2457, DOI:
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