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MeaSuRe

Following Protein Diffusion in Photosynthetic Membranes with Super Resolution

Total Cost €

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EC-Contrib. €

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Partnership

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 MeaSuRe project word cloud

Explore the words cloud of the MeaSuRe project. It provides you a very rough idea of what is the project "MeaSuRe" about.

parajo    techniques    nanophotonics    fluctuating    wientjes    insights    biophysics    photosynthetic    regime    chloroplasts    structural    nanoantennas    give    capacity    nanometers    resolution    expert    spectroscopy    illumination    super    movement    plants    crowded    membrane    simultaneously    regulated    huge    biophysicists    measuring    laboratory    barcelona    limitation    dr    tens    diffraction    optimize    biomolecules    amerongen    contrast    fcs    protein    plasmonic    confine    nf    ultrasensitive    fact    van    harvesting    started    performed    hulst    wageningen    nanoantenna    light    combination    instance    photonic    sciences    university    amount    fluorescence    nanometer    supervisor    mf    prof    photosynthesis    complexes    accessible    mobility    environment    owing    redistribution    outcome    little    directional    led    photosystems    correlation    proteins    dynamics    size    garcia    lagging    date    nanobioimaging    nanoscale    limit    diffusion    scientists    optical    biosensing    membranes    functional    overcome   

Project "MeaSuRe" data sheet

The following table provides information about the project.

Coordinator
WAGENINGEN UNIVERSITY 

Organization address
address: DROEVENDAALSESTEEG 4
city: WAGENINGEN
postcode: 6708 PB
website: http://www.wageningenur.nl/nl.htm

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-14   to  2017-10-23

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    WAGENINGEN UNIVERSITY NL (WAGENINGEN) coordinator 177˙598.00

Map

 Project objective

The regulated diffusion of light-harvesting complexes in photosynthetic membranes is essential for photosynthesis, for instance for the redistribution of light-harvesting complexes between Photosystems I and II. To date, however, little is understood about the mobility of these proteins through the highly crowded membrane environment. In contrast to the huge amount of structural research that has been performed on biomolecules in the past, research on the dynamics is lagging far behind. The major limitation is the fact that the nanometer size regime of biomolecules is not accessible by classical optical techniques owing to the diffraction limit of light. To overcome this problem, we propose to use plasmonic nanoantennas, which are able to confine light at the nanoscale. In combination with Fluorescence Correlation Spectroscopy (FCS) this will allow measuring protein mobility in photosynthetic membranes with high, tens of nanometers, resolution. Directional and functional protein movement will be induced by illumination of the chloroplasts using specific light conditions; simultaneously following the protein movement will give new insights in how plants optimize their light harvesting capacity under fluctuating light conditions. The new nanoantenna-FCS based method, which we will develop to measure the diffusion of membrane proteins with nanometer resolution, has the potential to become widely used for nanobioimaging and ultrasensitive biosensing. This research will be performed by Dr. E Wientjes in the Laboratory of Biophysics of Wageningen University led by photosynthesis expert Prof. H van Amerongen. A long-term collaboration will be started with Wientjes current supervisor Prof. NF van Hulst and Prof. MF Garcia-Parajo from the Institute of Photonic Sciences in Barcelona who are leading scientists in nanophotonics. The outcome of this project will provide biophysicists with a new method to study membrane protein dynamics with super resolution.

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The information about "MEASURE" are provided by the European Opendata Portal: CORDIS opendata.

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