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NANOCARB

Self-selection of a multivalent nanosystem for carbohydrate recognition

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 NANOCARB project word cloud

Explore the words cloud of the NANOCARB project. It provides you a very rough idea of what is the project "NANOCARB" about.

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Project "NANOCARB" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI PADOVA 

Organization address
address: VIA 8 FEBBRAIO 2
city: PADOVA
postcode: 35122
website: www.unipd.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.chimica.unipd.it/leonard.prins/
 Total cost 180˙277 €
 EC max contribution 180˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-04-15   to  2017-04-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) coordinator 180˙277.00

Map

 Project objective

The main objective of the NANOCARB project is to prepare the experienced researcher (ER) for an independent career through the implementation of a frontier research project and a training programme covering all aspects that are required for running a research group. The NANOCARB project has the scientific objective to build up an original method for the development of an innovative class of carbohydrate receptors using dynamic combinatorial chemistry (DCC) on the surface of a gold nanoparticle. Molecular receptors capable of carbohydrate recognition have a great potential in diagnostics and therapeutics. However, this prospective is still remote as it has turned out that designing synthetic receptor molecules able to selectively bind carbohydrates in water is very difficult. The distinguishing feature of this project is that the recognition site for the carbohydrate target is spontaneously formed, driven by the carbohydrate target itself. The self-selected recognition units will then be immobilized covalently on the gold nanoparticle, yielding a multivalent nanosystem able to recognize its target also in vivo. The project is on the interphase between chemistry, biology and nanotechnology providing an excellent opportunity for the experienced researcher (ER) to develop skills in these areas. Training excellence within the context of becoming independent researcher will involve manuscript and research proposal preparation, public engagement, IPR issues, networking, and conference organization. The project also benefits from external input and a secondment from other groups (Prof. Lay, University of Milan and Prof. Lombardi, University of Piemonte Orientale) in order to fill lacunes not available at the host institution. The combined package of scientific and training objectives will make the NANOCARB project an excellent platform for kick-starting the independent career of the ER and generating a strong visibility to the host institution.

 Publications

year authors and title journal last update
List of publications.
2017 Jack Chen, Subhabrata Maiti, Ilaria Fortunati, Camilla Ferrante, Leonard J. Prins
Temporal Control over Transient Chemical Systems using Structurally Diverse Chemical Fuels
published pages: , ISSN: 0947-6539, DOI: 10.1002/chem.201701533
Chemistry - A European Journal 2019-07-23
2016 Subhabrata Maiti, Ilaria Fortunati, Camilla Ferrante, Paolo Scrimin, Leonard J. Prins
Dissipative self-assembly of vesicular nanoreactors
published pages: 725-731, ISSN: 1755-4330, DOI: 10.1038/nchem.2511
Nature Chemistry 8/7 2019-07-23
2017 Flavio della Sala, Simona Neri, Subhabrata Maiti, Jack L-Y Chen, Leonard J Prins
Transient self-assembly of molecular nanostructures driven by chemical fuels
published pages: 27-33, ISSN: 0958-1669, DOI: 10.1016/j.copbio.2016.10.014
Current Opinion in Biotechnology 46 2019-07-23
2017 Subhabrata Maiti, Leonard J. Prins
A modular self-assembled sensing system for heavy metal ions with tunable sensitivity and selectivity
published pages: , ISSN: 0040-4020, DOI: 10.1016/j.tet.2017.05.028
Tetrahedron 2019-07-23

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The information about "NANOCARB" are provided by the European Opendata Portal: CORDIS opendata.

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