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Analysis of sugar- and osmo-signalling mechanisms in cell wall integrity maintenance

Total Cost €


EC-Contrib. €






Project "SugarOsmoSignalling" data sheet

The following table provides information about the project.


Organization address
postcode: 7491

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Project website
 Total cost 208˙400 €
 EC max contribution 208˙400 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-16   to  2018-03-15


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Cell walls provide plant cells with structural support during growth and differentiation as well as with protection against environmental stress. Cell wall composition and structure is adapted to these functional requirements by a dedicated mechanism to maintain cell wall integrity (CWI). The available evidence suggests that the CWI mechanism is an important regulator of cell wall and carbohydrate metabolism and that signalling of sugar levels and osmotic conditions is vital for its function. Furthermore, interdependencies between pathogen defence and the CWI mechanism are becoming apparent. By performing a forward genetic screen in Arabidopsis, I will identify novel components involved in sugar-signalling in the context of CWI maintenance and pathogen defence. Using a combination of genetic mapping and next-generation sequencing, I will determine the identity of the components, whose specific activities will be identified through targeted functional analyses. In the second part of my project I will determine functions of the signalling metabolites trehalose-6-phosphate and glycerol-3-phophate in CWI maintenance and analyse the osmo-sensitive regulation of these functions. After characterizing time-dependent quantitative changes in metabolite levels and related enzyme activities upon impaired CWI and in combination with osmotic support, I will examine specific functions of metabolites / enzymes by analysing developmental, hormonal and structural responses in Arabidopsis overexpression and knockout lines. This project takes advantage of CWI maintenance involvement in a variety of biological processes to identify signalling components and osmo-sensitive mechanisms for the coordination of carbohydrate metabolism with cell wall metabolism and pathogen defence. The knowledge generated in this project will provide novel functional insights into metabolic processes relevant for facilitating bioenergy production and increasing the yield of food crops.


year authors and title journal last update
List of publications.
2018 Nora Gigli-Bisceglia, Timo Engelsdorf, Miroslav Strnad, Lauri Vaahtera, Amel Jamoune, Leila Alipanah, Ondrej Novak, Jan Hejatko, Thorsten Hamann
Cellulose biosynthesis inhibition reduces cell cycle activity in a nitrate reductase- and cytokinin-dependent manner
published pages: , ISSN: , DOI:
Development in revision 2019-06-13

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The information about "SUGAROSMOSIGNALLING" are provided by the European Opendata Portal: CORDIS opendata.

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