Opendata, web and dolomites

H2020 projects about "knockout"

The page lists 68 projects related to the topic "knockout".

# achronym  title  year 
1 MitSyn Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s? 2015
2 CLOPRESS Renal Chloride Chanels and Blood Pressure Regulation 2015
3 GLUCOTOX Does reducing β-cell glucotoxicity increase the hyperglycaemia-lowering effect of physical exercise in type 2 diabetes? 2015
4 Class II PI3K Characterization of the signalling and physiological roles of the class II PI3Ks 2016
5 PneumoCompetence Unravelling the mechanisms of competence induction by antibiotic stress in Streptococcus pneumoniae 2015
6 WORMTUMORS Worm power: Can helminths modify the development of colorectal cancer? 2015
7 SugarOsmoSignalling Analysis of sugar- and osmo-signalling mechanisms in cell wall integrity maintenance 2016
8 CARiPSCTcells Generation of safe and efficient, off-the-shelf, chimeric antigen receptor (CAR)-engineered T cells for broad application 2015
9 TIME Time of damage in classic galactosemia: is prenatal toxicity a determinant factor? 2015
10 IntestineUb The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells 2016
11 PFSEXOME Identification of protein kinases and signalling pathways important for Plasmodium falciparum malaria transmission 2015
12 MISTRANSMITO Tissue-specific mitochondrial signaling and adaptations to mistranslation 2015
13 GENESIS GENEtic DiSsection of Innate Immune Sensing and Signalling 2015
14 CRISPAIR Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools 2016
15 ThDEFINE Re(defining) CD4+ T Cell Identities One Cell at a Time 2016
16 UNRAVEL Understanding the Role of Antisense lncRNA in Vernalization, Memory and Life History 2016
17 GolgiBiosSys Identification and characterisation of plant Golgi biosynthetic multiprotein systems 2016
18 CIRCLE Investigation of the role of CYLD in Chronic Lymphocytic Leukaemia 2016
19 MRCKa in cancer Targeting Cancer Cell Invasion and Metastasis by Inhibition of the Serine Kinase MRCKa 2016
20 CHROMATIX Role of epigenetic mechanisms in random X chromosome inactivation in vivo. 2016
21 BAC-STAR Bacterial Adhesion Control through Surface TArgeted Regulation 2017
22 TransGen RNA Transgenerational regulation of glucose metabolism by noncoding RNAs 2016
23 EpigenomeProgramming An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell 2016
24 ZMOD Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers 2016
25 ALS-Networks Defining functional networks of genetic causes for ALS and related neurodegenerative disorders 2017
26 BETA-BACT Beta-cell inflammation and dysfunction induced by bacterial translocation 2016
27 iNAPS Illuminating Neuronal-Astrocytic Pathways for Sleep homeostasis 2017
28 SymMech Unravelling the mechanisms behind bacterial symbiosis in insects 2017
29 MetResistance The role of tumour microenvironment in metastatic hormone-refractory prostate cancer 2017
30 StrainBooster Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories 2017
31 DIRECtA Targeting the Endocannabinoid System within Islets of Langerhans to Protect against Immune Destruction. 2018
32 GREEN-SPECIALISTS Specialised plant cell types via developmentally-controlled gene knockouts: a key step towards fully customised plants 2018
33 StressEBOV Ebola virus manipulation of the cellular stress responses 2017
34 CD4CRISPR A quorum sensing mechanism regulating CD4 T cell proliferation 2017
35 EASY Epigenetic approach for the treatment of obesity 2017
36 MalariaEgress Role of perforin-like proteins and phospholipases in malaria parasite egress 2018
37 HERPES Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability 2017
38 HemTree2.0 Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis 2017
39 deFIBER Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment 2018
40 noRAG-TOR Rag-independent regulation of mTOR by Amino Acids 2018
41 TECNEC Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy 2017
42 NO-STRESS Nitric oxide regulation of repolarisation in the heart: role of mechanical stress 2018
43 ORGANOMICS Reconstructing human cortex development and malformation with single-cell transcriptomics 2018
44 MeloCRISP Implementation of CRISPR/Cas9 technology in melon to edit fruit ripening and CMV resistant genes 2018
45 INTERGLU Dissecting mGlu5 receptor internalization pathways using genetic and pharmacological tools 2018
46 BREFMC2017 Deciphering the function(s) of the C-type lectin DCIR/CLEC4A in tuberculosis 2018
47 VIAR Virus-induced autophagy restriction 2018
48 transLEISHion A targeted knockout screen for identification of Leishmania membrane transporters required for infection of macrophages 2018
49 GLYMPHARMA Modulation of the glymphatic system: a novel tool for drug delivery to the central nervous system 2018
50 HDAC6_GEMM Development of a novel genetically engineered mouse model to study the role of HDAC6 in oncogenesis and metastasis of non-small cell lung cancer. 2018
51 DOUBLE EXPRESS Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease 2019
52 mTORmorS Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma 2019
53 EVOCLOCK From Evolution to Clockworks:Unravelling the molecular basis of circalunar clocks 2019
54 COR1-TCELL Analysis of the role for coronin 1-dependent cell density signalling in T-cell homeostasis 2019
55 REAP Repair of DNA lesions induced by platinum drugs 2019
56 MacrophInt Targeting integrin signaling in tumour-associated macrophages to combat cancer progression and resistance 2019
57 DECODE Decoding Context-Dependent Genetic Networks in vivo 2019
58 Renal Flow Flow-stimulated ion channel signalling in renal epithelia 2020
59 JOLI Using the jellyfish Clytia hemisphaerica to explore the first steps of meiosis by live-imaging. 2019
60 Hepatic Thermogenesi Study the functions of the hepatic sympathetic nerve and the receptor Adrb3 in liver-mediated adaptive thermogenesis. 2019
61 INTERGLP1 Dissecting GLP-1 receptor internalization pathways using genetic and pharmacological tools 2020
62 NUAGE Nucleolar regulation of longevity 2020
63 FunStructure Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease 2019
64 ChronicPain New Target and Drug Candidates for Alleviating Chronic Pain 2019
65 PHYRIST Physiological roles of the Ribotoxic Stress Response 2020
66 RARE MAPS Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease 2020
67 PhotoBoost A holistic approach to improve the photosynthetic perfromance and productivity of C3 crops under diverse environmental conditions 2020
68 GABARPET ImmunoPET directed to specific subtypes of GABAA receptors as strategy for molecular mapping of behaviour and mental illness 2020