Opendata, web and dolomites
H2020 projects about "knockout"
The page lists 68 projects related to the topic "knockout".
| # | |||
|---|---|---|---|
| 1 | MitSyn | Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s? | 2015 |
| 2 | CLOPRESS | Renal Chloride Chanels and Blood Pressure Regulation | 2015 |
| 3 | GLUCOTOX | Does reducing β-cell glucotoxicity increase the hyperglycaemia-lowering effect of physical exercise in type 2 diabetes? | 2015 |
| 4 | Class II PI3K | Characterization of the signalling and physiological roles of the class II PI3Ks | 2016 |
| 5 | PneumoCompetence | Unravelling the mechanisms of competence induction by antibiotic stress in Streptococcus pneumoniae | 2015 |
| 6 | WORMTUMORS | Worm power: Can helminths modify the development of colorectal cancer? | 2015 |
| 7 | SugarOsmoSignalling | Analysis of sugar- and osmo-signalling mechanisms in cell wall integrity maintenance | 2016 |
| 8 | CARiPSCTcells | Generation of safe and efficient, off-the-shelf, chimeric antigen receptor (CAR)-engineered T cells for broad application | 2015 |
| 9 | TIME | Time of damage in classic galactosemia: is prenatal toxicity a determinant factor? | 2015 |
| 10 | IntestineUb | The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells | 2016 |
| 11 | PFSEXOME | Identification of protein kinases and signalling pathways important for Plasmodium falciparum malaria transmission | 2015 |
| 12 | MISTRANSMITO | Tissue-specific mitochondrial signaling and adaptations to mistranslation | 2015 |
| 13 | GENESIS | GENEtic DiSsection of Innate Immune Sensing and Signalling | 2015 |
| 14 | CRISPAIR | Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools | 2016 |
| 15 | ThDEFINE | Re(defining) CD4+ T Cell Identities One Cell at a Time | 2016 |
| 16 | UNRAVEL | Understanding the Role of Antisense lncRNA in Vernalization, Memory and Life History | 2016 |
| 17 | GolgiBiosSys | Identification and characterisation of plant Golgi biosynthetic multiprotein systems | 2016 |
| 18 | CIRCLE | Investigation of the role of CYLD in Chronic Lymphocytic Leukaemia | 2016 |
| 19 | MRCKa in cancer | Targeting Cancer Cell Invasion and Metastasis by Inhibition of the Serine Kinase MRCKa | 2016 |
| 20 | CHROMATIX | Role of epigenetic mechanisms in random X chromosome inactivation in vivo. | 2016 |
| 21 | BAC-STAR | Bacterial Adhesion Control through Surface TArgeted Regulation | 2017 |
| 22 | TransGen RNA | Transgenerational regulation of glucose metabolism by noncoding RNAs | 2016 |
| 23 | EpigenomeProgramming | An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell | 2016 |
| 24 | ZMOD | Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers | 2016 |
| 25 | ALS-Networks | Defining functional networks of genetic causes for ALS and related neurodegenerative disorders | 2017 |
| 26 | BETA-BACT | Beta-cell inflammation and dysfunction induced by bacterial translocation | 2016 |
| 27 | iNAPS | Illuminating Neuronal-Astrocytic Pathways for Sleep homeostasis | 2017 |
| 28 | SymMech | Unravelling the mechanisms behind bacterial symbiosis in insects | 2017 |
| 29 | MetResistance | The role of tumour microenvironment in metastatic hormone-refractory prostate cancer | 2017 |
| 30 | StrainBooster | Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories | 2017 |
| 31 | DIRECtA | Targeting the Endocannabinoid System within Islets of Langerhans to Protect against Immune Destruction. | 2018 |
| 32 | GREEN-SPECIALISTS | Specialised plant cell types via developmentally-controlled gene knockouts: a key step towards fully customised plants | 2018 |
| 33 | StressEBOV | Ebola virus manipulation of the cellular stress responses | 2017 |
| 34 | CD4CRISPR | A quorum sensing mechanism regulating CD4 T cell proliferation | 2017 |
| 35 | EASY | Epigenetic approach for the treatment of obesity | 2017 |
| 36 | MalariaEgress | Role of perforin-like proteins and phospholipases in malaria parasite egress | 2018 |
| 37 | HERPES | Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability | 2017 |
| 38 | HemTree2.0 | Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis | 2017 |
| 39 | deFIBER | Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment | 2018 |
| 40 | noRAG-TOR | Rag-independent regulation of mTOR by Amino Acids | 2018 |
| 41 | TECNEC | Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy | 2017 |
| 42 | NO-STRESS | Nitric oxide regulation of repolarisation in the heart: role of mechanical stress | 2018 |
| 43 | ORGANOMICS | Reconstructing human cortex development and malformation with single-cell transcriptomics | 2018 |
| 44 | MeloCRISP | Implementation of CRISPR/Cas9 technology in melon to edit fruit ripening and CMV resistant genes | 2018 |
| 45 | INTERGLU | Dissecting mGlu5 receptor internalization pathways using genetic and pharmacological tools | 2018 |
| 46 | BREFMC2017 | Deciphering the function(s) of the C-type lectin DCIR/CLEC4A in tuberculosis | 2018 |
| 47 | VIAR | Virus-induced autophagy restriction | 2018 |
| 48 | transLEISHion | A targeted knockout screen for identification of Leishmania membrane transporters required for infection of macrophages | 2018 |
| 49 | GLYMPHARMA | Modulation of the glymphatic system: a novel tool for drug delivery to the central nervous system | 2018 |
| 50 | HDAC6_GEMM | Development of a novel genetically engineered mouse model to study the role of HDAC6 in oncogenesis and metastasis of non-small cell lung cancer. | 2018 |
| 51 | DOUBLE EXPRESS | Gene expression level as a keystone to understanding gene duplication: evolutionary constraints, opportunities, and disease | 2019 |
| 52 | mTORmorS | Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma | 2019 |
| 53 | EVOCLOCK | From Evolution to Clockworks:Unravelling the molecular basis of circalunar clocks | 2019 |
| 54 | COR1-TCELL | Analysis of the role for coronin 1-dependent cell density signalling in T-cell homeostasis | 2019 |
| 55 | REAP | Repair of DNA lesions induced by platinum drugs | 2019 |
| 56 | MacrophInt | Targeting integrin signaling in tumour-associated macrophages to combat cancer progression and resistance | 2019 |
| 57 | DECODE | Decoding Context-Dependent Genetic Networks in vivo | 2019 |
| 58 | Renal Flow | Flow-stimulated ion channel signalling in renal epithelia | 2020 |
| 59 | JOLI | Using the jellyfish Clytia hemisphaerica to explore the first steps of meiosis by live-imaging. | 2019 |
| 60 | Hepatic Thermogenesi | Study the functions of the hepatic sympathetic nerve and the receptor Adrb3 in liver-mediated adaptive thermogenesis. | 2019 |
| 61 | INTERGLP1 | Dissecting GLP-1 receptor internalization pathways using genetic and pharmacological tools | 2020 |
| 62 | NUAGE | Nucleolar regulation of longevity | 2020 |
| 63 | FunStructure | Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease | 2019 |
| 64 | ChronicPain | New Target and Drug Candidates for Alleviating Chronic Pain | 2019 |
| 65 | PHYRIST | Physiological roles of the Ribotoxic Stress Response | 2020 |
| 66 | RARE MAPS | Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease | 2020 |
| 67 | PhotoBoost | A holistic approach to improve the photosynthetic perfromance and productivity of C3 crops under diverse environmental conditions | 2020 |
| 68 | GABARPET | ImmunoPET directed to specific subtypes of GABAA receptors as strategy for molecular mapping of behaviour and mental illness | 2020 |