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GLOID

Genetic and Lifestyle Origins of Inflammation in Depression

Total Cost €

0

EC-Contrib. €

0

Partnership

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 GLOID project word cloud

Explore the words cloud of the GLOID project. It provides you a very rough idea of what is the project "GLOID" about.

sk    public    levels    wellbeing    remission    least    treatments    treating    contribution    interact    causes    unknown    nesda    inflammatory    prevention    group    disseminate    researcher    me    amsterdam    pi    statistical    depression    questions    lifelong    content    scientific    inflammation    produces    training    broadly    university    vu    professor    data    lifestyle    independent    investigation    conference    longitudinal    substantial    unhealthy    people    unclear    genetic    status    polymorphisms    world    presentations    genetics    anxiety    leaders    individual    unanswered    experts    mediators    scores    academic    curie    expertise    formal    contributes    complete    behaviours    marie    societal    penninx    strategies    blood    suboptimal    peer    fellowship    hypothesis    causal    interaction    source    risk    mentoring    collaborate    odowska    profile    progress    elevated    undertaking    psychobiological    polygenic    health    environmental    epidemiology    sophisticated    netherlands    articles   

Project "GLOID" data sheet

The following table provides information about the project.

Coordinator
STICHTING VUMC 

Organization address
address: DE BOELELAAN 1117
city: AMSTERDAM
postcode: 1081 HV
website: www.vumc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website https://sarahhiles.wordpress.com/gloid-project/
 Total cost 133˙199 €
 EC max contribution 133˙199 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2016-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VUMC NL (AMSTERDAM) coordinator 73˙013.00
2    STICHTING VU NL (AMSTERDAM) participant 60˙186.00

Map

 Project objective

Depression produces substantial societal costs. Its cause is unknown and treatments are suboptimal. Inflammation may be involved in depression. People with depression have elevated levels of inflammatory mediators in the blood, although it is unclear whether the source is genetic, environmental, or some interaction. A likely environmental source is unhealthy lifestyle behaviours. To progress the field, studies must more directly test the causal status of the inflammatory hypothesis of depression; specifically, whether inflammation-related genetic polymorphisms or whole polygenic risk scores interact with unhealthy lifestyle in depression and its remission.

I will address these unanswered questions in a Marie SkÅ‚odowska-Curie European Fellowship with Professor Penninx’s research group at VU University Amsterdam; world-leaders in the investigation of psychobiological causes of depression. I will collaborate with experts in genetic epidemiology and the inflammatory hypothesis of depression and complete sophisticated statistical analysis of data from the longitudinal Netherlands Study of Depression and Anxiety (NESDA; PI Professor Penninx). It will result in at least four peer-reviewed research articles, related conference presentations, and opportunities to more broadly disseminate the findings.

Undertaking this research along with formal training and mentoring will enhance my academic profile, scientific experience, and content expertise in the psychobiological causes of depression, to enable me to develop into an independent, leading researcher. The proposed research contributes to the EU priority of addressing “societal challenges” to improve lifelong health and wellbeing of all. Providing evidence for the contribution of genetics, inflammation and unhealthy lifestyle to depression will provide opportunities for identifying people at risk of depression, treating depression, and developing individual and public health prevention strategies.

 Publications

year authors and title journal last update
List of publications.
2016 S. A. Hiles, F. Lamers, Y. Milaneschi, B. W. J. H. Penninx
Sit, step, sweat: longitudinal associations between physical activity patterns, anxiety and depression
published pages: 1-12, ISSN: 0033-2917, DOI: 10.1017/S0033291716003548
Psychological Medicine 2019-07-24
2016 Sarah A Hiles; Femke Lamers; Yuri Milaneschi; Brenda WJH Penninx
Health behaviours, depression and anxiety
published pages: , ISSN: , DOI:
Annual NESDA Day 2019-07-24
2016 Sarah A. Hiles; Dora Révész; Femke Lamers; Erik Giltay; Brenda WJH Penninx
Metabolic dysregulation in depression and anxiety: Associations over time
published pages: , ISSN: , DOI:
International Society for Nutritional Psychiatry Research Workshop. Nutritional Psychiatry: Prevention, Treatment and Mechanisms 2019-07-24
2016 Sarah A Hiles
Sarah Hiles: Publication summaries
published pages: , ISSN: , DOI:
2019-07-24
2016 Sarah A Hiles; Femke Lamers; Yuri Milaneschi; Brenda WJH Penninx
Does unhealthy lifestyle predict course of major depressive disorder?
published pages: , ISSN: , DOI:
International Society for Bipolar Disorder 2019-07-24
2016 Sarah A Hiles; Dora Révész; Femke Lamers; Erik Giltay; Brenda WJH Penninx
Bi-directional longitudinal associations of metabolic syndrome with depression, anxiety and antidepressant use
published pages: , ISSN: , DOI:
American Psychosomatic Society Annual Meeting 2019-07-24
2015 Sarah A Hiles; Dóra Révész; Femke Lamers; Brenda WJH Penninx
Metabolic syndrome, depression and anxiety: Associations over six years
published pages: , ISSN: , DOI:
Annual NESDA Day 2019-07-24
2016 Sarah A. Hiles; Femke Lamers
Grant writing, fellowships and experiences abroad
published pages: , ISSN: , DOI:
Workshop - VUmc Department of Psychiatry 2019-07-24
2016 Sarah A. Hiles, Dóra Révész, Femke Lamers, Erik Giltay, Brenda W. J. H. Penninx
BIDIRECTIONAL PROSPECTIVE ASSOCIATIONS OF METABOLIC SYNDROME COMPONENTS WITH DEPRESSION, ANXIETY, AND ANTIDEPRESSANT USE
published pages: , ISSN: 1091-4269, DOI: 10.1002/da.22512
Depression and Anxiety 2019-07-24
2016 Mandy X. Hu, Femke Lamers, Sarah A. Hiles, Brenda W.J.H. Penninx, Eco J.C. de Geus
Basal autonomic activity, stress reactivity, and increases in metabolic syndrome components over time
published pages: 119-126, ISSN: 0306-4530, DOI: 10.1016/j.psyneuen.2016.05.018
Psychoneuroendocrinology 71 2019-07-24
2016 Sarah A Hiles; Femke Lamers; Yuri Milaneschi; Brenda WJH Penninx
Unhealthy lifestyle and the course of major depressive disorder
published pages: , ISSN: , DOI:
VUmc Science Exchange Day 2019-07-24
2016 Sarah A. Hiles
Marie Skłodowska-Curie Fellowships: Perspectives of a current fellow
published pages: , ISSN: , DOI:
VU University Grants Desk Information Session 2019-07-24
2015 Sarah A Hiles
Flame and tears: Inflammation in depression and consequences for physical health
published pages: , ISSN: , DOI:
2019-07-24
2016 Sarah A Hiles; Femke Lamers; Yuri Milaneschi; Brenda WJH Penninx
Sit, step, sweat: Associations of anxiety and depression with sedentary behaviour and physical activity over six years
published pages: , ISSN: , DOI:
American Psychosomatic Society Annual Meeting 2019-07-24
2015 Sarah A Hiles; Dora Révész; Femke Lamers; Erik Giltay; Brenda WJH Penninx
Longitudinal associations between metabolic syndrome, depression and anxiety
published pages: , ISSN: , DOI:
International Federation of Psychiatric Epidemiology Bi-annual 2019-07-24

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The information about "GLOID" are provided by the European Opendata Portal: CORDIS opendata.

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