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NanoEnHanCeMent SIGNED

Nanoparticle Enhanced Hadron-therapy: a Comprehensive Mechanistic description

Total Cost €


EC-Contrib. €






 NanoEnHanCeMent project word cloud

Explore the words cloud of the NanoEnHanCeMent project. It provides you a very rough idea of what is the project "NanoEnHanCeMent" about.

envisaged    mechanisms    uncover    treatment    science    dose    community    acquisition    responsible    experimental    beams    disseminate    radiotherapies    relies    monte    occurring    initio    enhanced    basic    skills    interfaced    complete    theory    track    ab    meet    scientific    description    hadron    therapy    effect    experiment    extended    physics    mechanistic    societal    outreach    tuned    beam    communication    cancer    clinical    chemistry    semiempirical    encompasses    transferable    nanoparticle    microscopic    investment    phenomena    nanoparticles    action    tools    proper    effectiveness    ion    radiotherapy    deepening    accelerated    series    carlo    learning    cells    unknown    mastered    citizenship    biological    complementary    nanoenhancement    pointing    structure    integral    training    enhancement    simulation    conventional    superior    depends    researcher    chemical    physical    environment    physico    pave    radioenhancement    nanoscale    cooperation   

Project "NanoEnHanCeMent" data sheet

The following table provides information about the project.


Organization address
address: VIA SANTA CROCE 77
city: TRENTO
postcode: 38122

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 171˙473 €
 EC max contribution 171˙473 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-09-01   to  2022-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE BRUNO KESSLER IT (TRENTO) coordinator 171˙473.00


 Project objective

NanoEnHanCeMent (Nanoparticle Enhanced Hadron-therapy: a comprehensive Mechanistic description) is an action aimed to apply basic Physics and Chemistry methods to uncover the microscopic mechanisms behind nanoparticle enhancement of hadron-therapy for cancer treatment (or ion beam cancer therapy). Hadron-therapy (radiotherapy using accelerated ion beams) is one of the most advanced radiotherapies available, with superior dose delivery and biological effectiveness as compared to conventional radiotherapy. The increased effectiveness of hadron-therapy relies on physico-chemical phenomena occurring on the nanoscale. There is experimental evidence pointing out to nanoparticles enhancing the biological effects of ion beams. Since nanoparticles can be tuned to target cancer cells, they might be used to further improve hadron-therapy. However, it is still unknown how nanoparticles produce this effect. A proper exploitation of the nanoparticle radioenhancement in hadron-therapy depends on improving the understanding of the physico-chemical mechanisms responsible for it. In this project, a theory and modelling approach is proposed, in which a series of semiempirical and ab initio methods will be extended and interfaced with Monte Carlo track-structure simulation tools, in order to advance the basic understanding of the nanoparticle enhanced hadron-therapy physical and chemical mechanisms. The action also encompasses an integral training program for the Experienced Researcher, with a deepening in already mastered methods and learning of new methodologies, together with the acquisition of complementary and transferable skills, all this in an environment where theory, experiment and clinical applications meet. A complete communication and outreach program is also envisaged, to disseminate the results to the scientific community and also to show to the citizenship how the investment in basic science and European cooperation pave the way for addressing societal challenges.

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The information about "NANOENHANCEMENT" are provided by the European Opendata Portal: CORDIS opendata.

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