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NanoEnHanCeMent SIGNED

Nanoparticle Enhanced Hadron-therapy: a Comprehensive Mechanistic description

Total Cost €


EC-Contrib. €






 NanoEnHanCeMent project word cloud

Explore the words cloud of the NanoEnHanCeMent project. It provides you a very rough idea of what is the project "NanoEnHanCeMent" about.

action    science    communication    beam    skills    hadron    interfaced    investment    accelerated    structure    radiotherapies    phenomena    community    pointing    transferable    conventional    description    cells    physico    ion    depends    therapy    uncover    clinical    beams    nanoenhancement    theory    carlo    tools    learning    tuned    enhancement    meet    chemical    effect    chemistry    radiotherapy    deepening    mechanisms    basic    pave    envisaged    experiment    enhanced    mastered    nanoscale    ab    extended    disseminate    cooperation    series    acquisition    mechanistic    relies    societal    cancer    outreach    superior    physics    integral    researcher    training    dose    proper    unknown    occurring    semiempirical    biological    encompasses    nanoparticles    complementary    citizenship    physical    radioenhancement    nanoparticle    monte    initio    complete    experimental    treatment    environment    effectiveness    track    responsible    scientific    simulation    microscopic   

Project "NanoEnHanCeMent" data sheet

The following table provides information about the project.


Organization address
address: VIA SANTA CROCE 77
city: TRENTO
postcode: 38122

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 171˙473 €
 EC max contribution 171˙473 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-09-01   to  2022-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE BRUNO KESSLER IT (TRENTO) coordinator 171˙473.00


 Project objective

NanoEnHanCeMent (Nanoparticle Enhanced Hadron-therapy: a comprehensive Mechanistic description) is an action aimed to apply basic Physics and Chemistry methods to uncover the microscopic mechanisms behind nanoparticle enhancement of hadron-therapy for cancer treatment (or ion beam cancer therapy). Hadron-therapy (radiotherapy using accelerated ion beams) is one of the most advanced radiotherapies available, with superior dose delivery and biological effectiveness as compared to conventional radiotherapy. The increased effectiveness of hadron-therapy relies on physico-chemical phenomena occurring on the nanoscale. There is experimental evidence pointing out to nanoparticles enhancing the biological effects of ion beams. Since nanoparticles can be tuned to target cancer cells, they might be used to further improve hadron-therapy. However, it is still unknown how nanoparticles produce this effect. A proper exploitation of the nanoparticle radioenhancement in hadron-therapy depends on improving the understanding of the physico-chemical mechanisms responsible for it. In this project, a theory and modelling approach is proposed, in which a series of semiempirical and ab initio methods will be extended and interfaced with Monte Carlo track-structure simulation tools, in order to advance the basic understanding of the nanoparticle enhanced hadron-therapy physical and chemical mechanisms. The action also encompasses an integral training program for the Experienced Researcher, with a deepening in already mastered methods and learning of new methodologies, together with the acquisition of complementary and transferable skills, all this in an environment where theory, experiment and clinical applications meet. A complete communication and outreach program is also envisaged, to disseminate the results to the scientific community and also to show to the citizenship how the investment in basic science and European cooperation pave the way for addressing societal challenges.

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The information about "NANOENHANCEMENT" are provided by the European Opendata Portal: CORDIS opendata.

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