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NanoEnHanCeMent SIGNED

Nanoparticle Enhanced Hadron-therapy: a Comprehensive Mechanistic description

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 NanoEnHanCeMent project word cloud

Explore the words cloud of the NanoEnHanCeMent project. It provides you a very rough idea of what is the project "NanoEnHanCeMent" about.

therapy    hadron    ion    physics    uncover    biological    responsible    integral    physical    clinical    complementary    effect    interfaced    ab    cooperation    accelerated    phenomena    chemical    training    encompasses    investment    radioenhancement    enhancement    effectiveness    science    physico    radiotherapy    nanoscale    nanoparticle    mechanisms    description    deepening    researcher    theory    envisaged    complete    communication    learning    occurring    proper    radiotherapies    carlo    nanoenhancement    mastered    monte    pave    nanoparticles    experiment    cells    extended    societal    treatment    relies    community    pointing    semiempirical    environment    cancer    scientific    transferable    chemistry    tools    simulation    unknown    superior    beam    beams    disseminate    depends    basic    acquisition    structure    dose    meet    conventional    series    initio    track    citizenship    skills    tuned    experimental    enhanced    mechanistic    outreach    action    microscopic   

Project "NanoEnHanCeMent" data sheet

The following table provides information about the project.

Coordinator
FONDAZIONE BRUNO KESSLER 

Organization address
address: VIA SANTA CROCE 77
city: TRENTO
postcode: 38122
website: www.fbk.eu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 171˙473 €
 EC max contribution 171˙473 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-09-01   to  2022-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE BRUNO KESSLER IT (TRENTO) coordinator 171˙473.00

Map

 Project objective

NanoEnHanCeMent (Nanoparticle Enhanced Hadron-therapy: a comprehensive Mechanistic description) is an action aimed to apply basic Physics and Chemistry methods to uncover the microscopic mechanisms behind nanoparticle enhancement of hadron-therapy for cancer treatment (or ion beam cancer therapy). Hadron-therapy (radiotherapy using accelerated ion beams) is one of the most advanced radiotherapies available, with superior dose delivery and biological effectiveness as compared to conventional radiotherapy. The increased effectiveness of hadron-therapy relies on physico-chemical phenomena occurring on the nanoscale. There is experimental evidence pointing out to nanoparticles enhancing the biological effects of ion beams. Since nanoparticles can be tuned to target cancer cells, they might be used to further improve hadron-therapy. However, it is still unknown how nanoparticles produce this effect. A proper exploitation of the nanoparticle radioenhancement in hadron-therapy depends on improving the understanding of the physico-chemical mechanisms responsible for it. In this project, a theory and modelling approach is proposed, in which a series of semiempirical and ab initio methods will be extended and interfaced with Monte Carlo track-structure simulation tools, in order to advance the basic understanding of the nanoparticle enhanced hadron-therapy physical and chemical mechanisms. The action also encompasses an integral training program for the Experienced Researcher, with a deepening in already mastered methods and learning of new methodologies, together with the acquisition of complementary and transferable skills, all this in an environment where theory, experiment and clinical applications meet. A complete communication and outreach program is also envisaged, to disseminate the results to the scientific community and also to show to the citizenship how the investment in basic science and European cooperation pave the way for addressing societal challenges.

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The information about "NANOENHANCEMENT" are provided by the European Opendata Portal: CORDIS opendata.

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