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LIVING LASERS

Living cell lasers: intracellular lasing induced by natural and polymeric microscopic resonators

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

LIVING LASERS project word cloud

Explore the words cloud of the LIVING LASERS project. It provides you a very rough idea of what is the project "LIVING LASERS" about.

realized interdisciplinary coalesce gather resonators gain conceptual generate photonics explores laser device located optical introducing media entirely can bacteria versatile overcome start biology biological vitamins rigid biocompatible tool independent artificial single interface supervisor consequently nowadays synthetic nature prof internalization transfer malte physics modern feedback living microscopic sciences light active ways experiments limited cell harmful technologies external biophotonics cells turned boundaries material autonomous demonstrated lasing lasers

Project "LIVING LASERS" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS Organization address address: NORTH STREET 66 COLLEGE GATE city: ST ANDREWS postcode: KY16 9AJ website: www.st-andrews.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://gatherlab.wp.st-andrews.ac.uk/people/
Total cost	195˙454 €
EC max contribution	195˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2015
Duration (year-month-day)	from 2015-08-01 to 2017-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS Organization address address: NORTH STREET 66 COLLEGE GATE city: ST ANDREWS postcode: KY16 9AJ website: www.st-andrews.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (ST ANDREWS)	coordinator	195˙454.00

Map

Project objective

Can a living cell be turned into a laser? By aiming to coalesce biological cells with laser light, the most versatile tool that modern photonics has developed, LIVING LASERS explores entirely new ways to develop fully biocompatible lasers.

The ability of vitamins, bacteria and even living cells to generate laser light has been recently demonstrated by the supervisor of the project, Prof Malte Gather. However, these and other experiments with active biological gain media are so far limited by the rigid and synthetic nature of the optical resonators, an essential part of any laser device. Introducing lasing in living cells independent of external resonators necessitates a conceptual change of the laser design. This is realized by internalization of microscopic resonators that will transfer the optical feedback directly into the cell. It is the main goal of this interdisciplinary project, located at the interface between material sciences, laser physics, photonics and biology, to demonstrate autonomous single cell lasing. Consequently, LIVING LASERS can be expected to start a whole new field in biophotonics and will help to overcome the boundaries between living nature and nowadays highly artificial and harmful laser technologies.

Publications

List of publications.
year	authors and title	journal	last update
2017	Marcel Schubert Schubert, Malte C. Gather Microscopic intracellular lasers tag individual cells over several generations published pages: , ISSN: 1818-2259, DOI: 10.1117/2.1201704.006899	SPIE Newsroom	2019-07-24
2017	M Karl, C P Dietrich, M Schubert, I D W Samuel, G A Turnbull, M C Gather Single cell induced optical confinement in biological lasers published pages: 84005, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aa5367	Journal of Physics D: Applied Physics 50/8	2019-07-24
2017	Marcel Schubert, Klara Volckaert, Markus Karl, Andrew Morton, Philipp Liehm, Gareth B. Miles, Simon J. Powis, Malte C. Gather Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators published pages: 40877, ISSN: 2045-2322, DOI: 10.1038/srep40877	Scientific Reports 7	2019-07-24
2016	C. P. Dietrich, A. Steude, L. Tropf, M. Schubert, N. M. Kronenberg, K. Ostermann, S. HoÂ fling, M. C. Gather An exciton-polariton laser based on biologically produced fluorescent protein published pages: e1600666-e160066, ISSN: 2375-2548, DOI: 10.1126/sciadv.1600666	Science Advances 2/8	2019-07-24
2016	Markus Karl, Guy L. Whitworth, Marcel Schubert, Christof P. Dietrich, Ifor D. W. Samuel, Graham A. Turnbull, Malte C. Gather Optofluidic distributed feedback lasers with evanescent pumping: Reduced threshold and angular dispersion analysis published pages: 261101, ISSN: 0003-6951, DOI: 10.1063/1.4954650	Applied Physics Letters 108/26	2019-07-24
2017	Christof P. Dietrich, Anja Steude, Marcel Schubert, JÃ¼rgen Ohmer, Utz Fischer, Sven HÃ¶fling, Malte C. Gather Strong Coupling in Fully Tunable Microcavities Filled with Biologically Produced Fluorescent Proteins published pages: 1600659, ISSN: 2195-1071, DOI: 10.1002/adom.201600659	Advanced Optical Materials 5/1	2019-07-24

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