Explore the words cloud of the PHAGECOM project. It provides you a very rough idea of what is the project "PHAGECOM" about.
The following table provides information about the project.
THE UNIVERSITY OF EXETER
|Coordinator Country||United Kingdom [UK]|
|Total cost||183˙454 €|
|EC max contribution||183˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2016-01-01 to 2017-12-31|
Take a look of project's partnership.
|1||THE UNIVERSITY OF EXETER||UK (EXETER)||coordinator||183˙454.00|
CRISPR-Cas is one of several distinct bacterial defence mechanisms that provide immunity against viruses (phages) and other mobile genetic elements (MGEs; e.g. plasmids). My research aims at understanding how CRISPR-Cas-mediated immunity is affected by the complexity of MGE communities. Using evolution assays and deep sequencing techniques I aim to study (i) the evolution of CRISPR-Cas-mediated immunity in a complex MGE community (i.e. multiple phages and plasmids), and (ii) determine the associated co-evolutionary dynamics. The proposed research is highly multidisciplinary and will perfectly complement my background in biochemistry and molecular biology. It also allows me to establish collaborations with academic and industrial partners to realize applications in dairy industry and phage therapy. The project will be pivotal for my personal development to become an independent researcher and offers me the unique opportunity to work in one of the most prominent microbial ecology and evolution laboratories worldwide, based at the Biosciences Department at the University of Exeter. Biosciences is a leading institute in evolutionary biology, microbiology and ecology that provides excellent opportunities for academic training and personal career development. I will be exposed to novel ideas and input from renowned researchers belonging to scientific disciplines unrelated to my own background, offering exciting opportunities for knowledge exchange and will have a strong impact on my personal and scientific development. Furthermore, I aim to establish a series of lectures for the general public throughout 2015 (the Year of the Phage) to emphasize the importance of phage research for many aspects of our society, including industry and medicine.
|year||authors and title||journal||last update|
Stineke van Houte, Angus Buckling, Edze R. Westra
Evolutionary Ecology of Prokaryotic Immune Mechanisms
published pages: 745-763, ISSN: 1092-2172, DOI: 10.1128/MMBR.00011-16
|Microbiology and Molecular Biology Reviews 80/3||2019-06-18|
Daniel Morley, Jenny M. Broniewski, Edze R. Westra, Angus Buckling, Stineke van Houte
Host diversity limits the evolution of parasite local adaptation
published pages: 1756-1763, ISSN: 0962-1083, DOI: 10.1111/mec.13917
|Molecular Ecology 26/7||2019-06-18|
Stineke van Houte, Alice K. E. Ekroth, Jenny M. Broniewski, HÃ©lÃ¨ne Chabas, Ben Ashby, Joseph Bondy-Denomy, Sylvain Gandon, Mike Boots, Steve Paterson, Angus Buckling, Edze R. Westra
The diversity-generating benefits of a prokaryotic adaptive immune system
published pages: 385-388, ISSN: 0028-0836, DOI: 10.1038/nature17436
Edze R. Westra, Andrea J. Dowling, Jenny M. Broniewski, Stineke van Houte
Evolution and Ecology of CRISPR
published pages: 307-331, ISSN: 1543-592X, DOI: 10.1146/annurev-ecolsys-121415-032428
|Annual Review of Ecology, Evolution, and Systematics 47/1||2019-06-18|
HÃ©lÃ¨ne Chabas, Stineke van Houte, Nina Molin HÃ¸yland-Kroghsbo, Angus Buckling, Edze R. Westra
Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies
published pages: 20160721, ISSN: 0962-8452, DOI: 10.1098/rspb.2016.0721
|Proceedings of the Royal Society B: Biological Sciences 283/1837||2019-06-18|
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The information about "PHAGECOM" are provided by the European Opendata Portal: CORDIS opendata.