Opendata, web and dolomites


Scale-up of an Advanced Manufacturing process to produce a Pharmaceutical product Application (SAMPA).

Total Cost €


EC-Contrib. €






Project "SAMPA" data sheet

The following table provides information about the project.


Organization address
city: DUBLIN
postcode: 9

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website
 Total cost 2˙307˙500 €
 EC max contribution 1˙600˙000 € (69%)
 Programme 1. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-2-2014
 Funding Scheme SME-2
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2017-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    SIGMOID PHARMA LIMITED IE (DUBLIN) coordinator 1˙600˙000.00


 Project objective

Sigmoid Pharma has developed an innovative product, CyCol®, to treat patients with moderate-severe ulcerative colitis, a disease that affects 1 million patients in Europe. CyCol® is enabled using Sigmoid’s proprietary SmPill® nanoemulsion-based technology to target a known and powerful drug, cyclosporine, directly to inflamed colons. In Phase II human studies, CyCol® was proven to be effective and safe. CyCol®, on oral product, will compete with injected, expensive drugs that have a risk of serious side effects.

Successful development and commercialisation of CyCol® will pivot on scaling up the advanced manufacturing process from the current ~5kg to the ~50kg batch size required for Phase III human studies.

SAMPA (Scale-up of an Advanced Manufacturing process to produce a Pharmaceutical product Application) project is focused on achieving 50kg batches. It will involve leading EU-based specialist SME technology and equipment suppliers as well as a number of knowledge providers. The requested budget is €1.6M and will be completed in 21 months.

Successful completion of this project will retain and enhance intellectual property and know-how in Sigmoid, increase long term high skill jobs. In parallel, the project will unlock the value inherent not only of CyCol®, but also the underlying SmPill® technology platform. Furthermore, the project will increase the probability of overall company success and increase significantly the NPV to more than €500M.


List of deliverables.
Project website Websites, patent fillings, videos etc. 2019-11-28 17:28:20

Take a look to the deliverables list in detail:  detailed list of SAMPA deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SAMPA" project.

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The information about "SAMPA" are provided by the European Opendata Portal: CORDIS opendata.

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