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CellScreenChip

All-in-One Cell Screening Chip: Device for Affordable High-Throughput Cell Screenings

Total Cost €

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EC-Contrib. €

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Partnership

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Project "CellScreenChip" data sheet

The following table provides information about the project.

Coordinator
KARLSRUHER INSTITUT FUER TECHNOLOGIE 

Organization address
address: KAISERSTRASSE 12
city: KARLSRUHE
postcode: 76131
website: www.kit.edu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-10-01   to  2017-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KARLSRUHER INSTITUT FUER TECHNOLOGIE DE (KARLSRUHE) coordinator 150˙000.00

Map

 Project objective

Experiments with live cells are fundamentally important in biology, pharmaceutical industry, biotechnology or in medicine and diagnostics. One important example of cell experiments is the prescreening of cells from cancer biopsies with anticancer drugs in order to identify the most effective and least toxic combination of drugs for a particular patient also known as personalized medicine.

The goal of this ERC Proof-of-Concept project is to develop, fabricate and optimize a device (CellScreenChip) for performing miniaturized, parallel and, therefore, more affordable and faster cell screening experiments for the areas of diagnostics and personalized medicine. Applications of the CellScreenChip include (but not limited to) cell based disease diagnosis (e.g. cancer diagnostics), drug screening (e.g. body on a chip) or personalized medicine (e.g. personalized drug compatibility tests). The CellScreenChip will be based on our recent development of the superhydrophobic-superhydrophilic micropatterning methods and the ability to create high-density arrays of droplet microreservoirs on superhydrophobic-superhydrophilic patterns that can be used for parallelized and miniaturized cell experiments.

 Publications

year authors and title journal last update
List of publications.
2016 Anna A. Popova, Konstantin Demir, Titus Genisius Hartanto, Eric Schmitt, Pavel A. Levkin
Droplet-microarray on superhydrophobic–superhydrophilic patterns for high-throughput live cell screenings
published pages: 38263-38276, ISSN: 2046-2069, DOI: 10.1039/C6RA06011K
RSC Adv. 6/44 2019-07-25
2015 Anna A. Popova, Sebastian M. Schillo, Konstantin Demir, Erica Ueda, A. Nesterov-Mueller, Pavel A. Levkin
Droplet-Array (DA) Sandwich Chip: A Versatile Platform for High-Throughput Cell Screening Based on Superhydrophobic-Superhydrophilic Micropatterning
published pages: 5217-5222, ISSN: 0935-9648, DOI: 10.1002/adma.201502115
Advanced Materials 27/35 2019-07-25

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The information about "CELLSCREENCHIP" are provided by the European Opendata Portal: CORDIS opendata.

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