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RCC-TEST

A breakthrough in Renal Cell Carcinoma: Personalized RCC-Test

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 RCC-TEST project word cloud

Explore the words cloud of the RCC-TEST project. It provides you a very rough idea of what is the project "RCC-TEST" about.

treatments    tumor    shown    diagnostic    models    patients    radical    therapeutic    commercial    oncology    expenses    thereby    vitro    combined    resistant    treatment    first    followed    exception    culture    spheroid    clinicians    multicellular    plan    immune    huge    investigation    tool    metastatic    80    immuno    3d    renal    rcc    prolong    efficient    business    therapies    personalized    15    solution    expensive    extremely    deliverable    opportunity    protocols    determinants    cells    spheroids    cell    prescribe    patient    trials    revolutionize    interpret    malignancies    drugs    rapid    cancer    resistance    updated    disease    sees    realized    post    starting    mrcc    international    resection    feasibility    surgical    therapy    breakthrough    diagnosed    ready    difficult    strategies    lives    appropriate    medical    market    clinical    fail    routine    icelltis    agents    effectiveness    industrial    30    prepare    time    reducing   

Project "RCC-TEST" data sheet

The following table provides information about the project.

Coordinator
ICELLTIS 

Organization address
address: 436 RUE PIERRE ET MARIE CURIE IMMEUBLE BIOSTEP
city: LABEGE
postcode: 31670
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.icelltis.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2016-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ICELLTIS FR (LABEGE) coordinator 50˙000.00

Map

 Project objective

In oncology today, only 10 to 15% of patients respond strongly to therapeutic treatments. Metastatic renal cell cancer (mRCC) is no exception. It is one of the most treatment-resistant malignancies. 30% of patients are diagnosed with a metastatic disease. In such cases, the only solution is a radical surgical resection of the tumor, followed by the necessary therapies. About 80% of cases fail to respond to current therapeutic agents. New protocols with combined immuno- and targeted therapies have shown highly promising results. However, it is extremely difficult to interpret these results. Each patient is different and defining the appropriate set of therapies for mRCC has become increasingly complex. RCC-TEST is a new in vitro diagnostic tool, which will revolutionize the RCC post-surgical treatment. It will allow for rapid and cost-effective testing of a therapy’s effectiveness for each patient, before starting complex and expensive therapeutic protocols. Clinicians will be able to prescribe personalized treatments and to prolong patients’ lives, thereby reducing medical expenses. The new test is based on the ICELLTIS breakthrough 3D multicellular tumor spheroids, which are specific to RCC. For the first time, these spheroids are composed of the patient’s own tumor and immune cells, which are key determinants for the efficient in vitro investigation of responses and resistance of tumor cells to medical drugs. During Phase 1, ICELLTIS will scale-up RCC-TEST in order to prepare and be ready for further European clinical trials. A market study will be realized in order to investigate new international market opportunities and to challenge different commercial strategies. The main deliverable will be an updated business plan. ICELLTIS sees a huge business opportunity to further exploit their know-how in 3D (spheroid) tumor cell culture models. This feasibility study is an essential first step before the routine clinical practice and industrial production.

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The information about "RCC-TEST" are provided by the European Opendata Portal: CORDIS opendata.

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