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RCC-TEST

A breakthrough in Renal Cell Carcinoma: Personalized RCC-Test

Total Cost €

0

EC-Contrib. €

0

Partnership

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 RCC-TEST project word cloud

Explore the words cloud of the RCC-TEST project. It provides you a very rough idea of what is the project "RCC-TEST" about.

efficient    15    cells    interpret    cell    therapeutic    vitro    followed    clinical    3d    spheroid    starting    therapies    medical    renal    tool    diagnostic    revolutionize    surgical    thereby    shown    trials    oncology    drugs    breakthrough    lives    rcc    international    immuno    first    strategies    combined    immune    cancer    models    exception    routine    expenses    clinicians    radical    resection    agents    mrcc    therapy    realized    opportunity    commercial    prolong    patients    patient    prescribe    plan    expensive    prepare    tumor    extremely    fail    reducing    80    appropriate    diagnosed    sees    huge    updated    resistant    feasibility    deliverable    difficult    30    protocols    industrial    investigation    business    effectiveness    culture    ready    market    rapid    determinants    resistance    time    treatments    multicellular    icelltis    spheroids    post    personalized    malignancies    solution    metastatic    disease    treatment   

Project "RCC-TEST" data sheet

The following table provides information about the project.

Coordinator
ICELLTIS 

Organization address
address: 436 RUE PIERRE ET MARIE CURIE IMMEUBLE BIOSTEP
city: LABEGE
postcode: 31670
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.icelltis.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2015
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2016-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ICELLTIS FR (LABEGE) coordinator 50˙000.00

Map

 Project objective

In oncology today, only 10 to 15% of patients respond strongly to therapeutic treatments. Metastatic renal cell cancer (mRCC) is no exception. It is one of the most treatment-resistant malignancies. 30% of patients are diagnosed with a metastatic disease. In such cases, the only solution is a radical surgical resection of the tumor, followed by the necessary therapies. About 80% of cases fail to respond to current therapeutic agents. New protocols with combined immuno- and targeted therapies have shown highly promising results. However, it is extremely difficult to interpret these results. Each patient is different and defining the appropriate set of therapies for mRCC has become increasingly complex. RCC-TEST is a new in vitro diagnostic tool, which will revolutionize the RCC post-surgical treatment. It will allow for rapid and cost-effective testing of a therapy’s effectiveness for each patient, before starting complex and expensive therapeutic protocols. Clinicians will be able to prescribe personalized treatments and to prolong patients’ lives, thereby reducing medical expenses. The new test is based on the ICELLTIS breakthrough 3D multicellular tumor spheroids, which are specific to RCC. For the first time, these spheroids are composed of the patient’s own tumor and immune cells, which are key determinants for the efficient in vitro investigation of responses and resistance of tumor cells to medical drugs. During Phase 1, ICELLTIS will scale-up RCC-TEST in order to prepare and be ready for further European clinical trials. A market study will be realized in order to investigate new international market opportunities and to challenge different commercial strategies. The main deliverable will be an updated business plan. ICELLTIS sees a huge business opportunity to further exploit their know-how in 3D (spheroid) tumor cell culture models. This feasibility study is an essential first step before the routine clinical practice and industrial production.

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The information about "RCC-TEST" are provided by the European Opendata Portal: CORDIS opendata.

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