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PAIR SIGNED

Physical Activity, Inflammation and Respiratory health: an integrative analysis of biological, behavioural and environmental determinants

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 PAIR project word cloud

Explore the words cloud of the PAIR project. It provides you a very rough idea of what is the project "PAIR" about.

mediating    mechanism    follow    lie    copd    individually    determinant    pollution    modify    spread    subjects    lung    co    chronic    ultraviolet    18    few    biological    impacts    public    largely    radiation    centre    seems    collected    hypotheses    environmental    modifiable    understudied    international    disease    cohorts    suggest    link    approximately    inflammation    data    administered    adult    decade    pulmonary    self    cross    frequency    ups    physical    implications    systemic    diseases    interviewer    inflammatory    echrs    sectional    reported    behavioural    limited    risk    air    examined    interleukin    influence    levels    effect    sapaldia    least    protein    serum    causal    measured    nfbc    ongoing    cohort    weak    questionnaires    diet    population    health    relationship    function    interactive    collaborations    adults    estimates    longitudinal    decline    smoking    obstructive    prospectively    bmi    associations    ecrhs    respiratory    greenness    incidence    spirometry    standards    combined    prevalent    economic    reactive    apart   

Project "PAIR" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country Spain [ES]
 Project website https://www.alecstudy.org/
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2018-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA ES (BARCELONA) coordinator 170˙121.00
2    FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL ES (BARCELONA) coordinator 0.00

Map

 Project objective

The link between physical activity with respiratory health and chronic obstructive pulmonary disease (COPD) remains weak and under-investigated. The limited existing research seems to suggest that systemic inflammation could lie in the causal pathway of this relationship, and that inflammatory-related conditions may modify this potential causal mechanism, although these hypotheses remain largely understudied.

This project will investigate 1) the effect of physical activity on lung function decline and COPD incidence in European adults, as well as 2) the mediating role of systemic inflammation and 3) the influence of biological (BMI, co-existing chronic inflammatory diseases), behavioural (diet, smoking) and environmental (air pollution, greenness, ultraviolet radiation) factors on this relationship.

Data from over 18,000 subjects from 3 large population-based adult cohorts (ECHRS, SAPALDIA and NFBC), for which data on lung function and physical activity were prospectively collected during at least two follow-ups approximately a decade apart, will be included. Lung function was measured by spirometry according to international standards. Physical activity frequency, duration and type was collected using self-reported (ECRHS and NFBC) or interviewer-administered (SAPALDIA) questionnaires. Systemic inflammation will be assessed using C-reactive protein and interleukin-6 levels in serum. Data on the inflammation-related factors of interest were collected by the cohorts or derived from previous/ongoing collaborations. Cross-sectional and longitudinal associations, and potential interactive effects, will be examined by centre/cohort and combined estimates will be derived.

Given that lung function is an important determinant of health and that physical activity is one of a very few prevalent individually-modifiable risk factors, the results of the proposed research have the potential for wide-spread implications as well as public health and economic impacts.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PAIR" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PAIR" are provided by the European Opendata Portal: CORDIS opendata.

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