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PAIR SIGNED

Physical Activity, Inflammation and Respiratory health: an integrative analysis of biological, behavioural and environmental determinants

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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0

 PAIR project word cloud

Explore the words cloud of the PAIR project. It provides you a very rough idea of what is the project "PAIR" about.

interviewer    disease    lie    implications    risk    understudied    interactive    weak    ongoing    self    interleukin    adult    questionnaires    reactive    hypotheses    inflammatory    incidence    administered    frequency    adults    obstructive    modifiable    associations    collected    reported    biological    radiation    standards    influence    ups    copd    centre    approximately    levels    lung    health    combined    pulmonary    largely    18    measured    pollution    diet    nfbc    data    estimates    decade    impacts    longitudinal    prevalent    decline    mechanism    cohort    air    prospectively    environmental    greenness    protein    link    systemic    spirometry    population    suggest    limited    effect    echrs    collaborations    subjects    follow    smoking    determinant    chronic    economic    function    serum    cohorts    relationship    inflammation    spread    few    modify    apart    least    physical    international    examined    causal    respiratory    public    seems    behavioural    individually    ecrhs    co    bmi    cross    diseases    sapaldia    ultraviolet    sectional    mediating   

Project "PAIR" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country Spain [ES]
 Project website https://www.alecstudy.org/
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2018-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA ES (BARCELONA) coordinator 170˙121.00
2    FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL ES (BARCELONA) coordinator 0.00

Map

 Project objective

The link between physical activity with respiratory health and chronic obstructive pulmonary disease (COPD) remains weak and under-investigated. The limited existing research seems to suggest that systemic inflammation could lie in the causal pathway of this relationship, and that inflammatory-related conditions may modify this potential causal mechanism, although these hypotheses remain largely understudied.

This project will investigate 1) the effect of physical activity on lung function decline and COPD incidence in European adults, as well as 2) the mediating role of systemic inflammation and 3) the influence of biological (BMI, co-existing chronic inflammatory diseases), behavioural (diet, smoking) and environmental (air pollution, greenness, ultraviolet radiation) factors on this relationship.

Data from over 18,000 subjects from 3 large population-based adult cohorts (ECHRS, SAPALDIA and NFBC), for which data on lung function and physical activity were prospectively collected during at least two follow-ups approximately a decade apart, will be included. Lung function was measured by spirometry according to international standards. Physical activity frequency, duration and type was collected using self-reported (ECRHS and NFBC) or interviewer-administered (SAPALDIA) questionnaires. Systemic inflammation will be assessed using C-reactive protein and interleukin-6 levels in serum. Data on the inflammation-related factors of interest were collected by the cohorts or derived from previous/ongoing collaborations. Cross-sectional and longitudinal associations, and potential interactive effects, will be examined by centre/cohort and combined estimates will be derived.

Given that lung function is an important determinant of health and that physical activity is one of a very few prevalent individually-modifiable risk factors, the results of the proposed research have the potential for wide-spread implications as well as public health and economic impacts.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PAIR" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PAIR" are provided by the European Opendata Portal: CORDIS opendata.

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