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REFLEX

Studying the role of the retrosplenial cortex in flexible learning

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "REFLEX" data sheet

The following table provides information about the project.

Coordinator
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION 

Organization address
address: MAULBEERSTRASSE 66
city: BASEL
postcode: 4058
website: www.fmi.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION CH (BASEL) coordinator 175˙419.00

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 Project objective

An emerging view of cortical area function posits that instead of primarily accounting for sensory processing and motor control, cortical areas might mediate flexible handling of sensory information and motor planning through learning and memory. In this project I propose to investigate this notion focusing on the function of retrosplenial cortex (RSC), a large, poorly understood and highly interconnected cortical area that interfaces with the hippocampal system. RSC has a key role in memory, and is thought to control flexible use of contextual information; it accounts for earliest memory deficits in Alzheimer’s disease. In primates, the RSC is positioned immediately behind the splenium and is centrally located between cortical sensory and limbic memory regions. It exhibits reciprocal connections with the hippocampal for-mation, anterior thalamic nucleus, and a network of dorso-medial cortical areas. RSC has a critical role in spatial and relational memory, and its interactions with the hippocampal system are essential for normal memory processing. The focus of this project is the hypothesis that the connectivity patterns of RSC account for what has been called its “translational” properties. I will first study the role of RSC in a generic form of flexible learning, then I will focus on spatial learning and analyse the capability of RSC to integrate information across multiple cue types and use these inputs to deal with the environment e.g. in allocentric-egocentric and egocen-tric-allocentric transformations.

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The information about "REFLEX" are provided by the European Opendata Portal: CORDIS opendata.

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