Explore the words cloud of the NCR project. It provides you a very rough idea of what is the project "NCR" about.
The following table provides information about the project.
THE UNIVERSITY OF MANCHESTER
|Coordinator Country||United Kingdom [UK]|
|Total cost||183˙454 €|
|EC max contribution||183˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-02-01 to 2019-01-31|
Take a look of project's partnership.
|1||THE UNIVERSITY OF MANCHESTER||UK (MANCHESTER)||coordinator||183˙454.00|
Nitrogen-containing molecules are among the most important class of compounds due to their relevance as medicines, agrochemicals, organic materials and dyes. Nitrogen-centered-radicals are a class of very versatile synthetic intermediates with great potential in the synthesis of N-containing molecules. However, to date, difficulties associated to their generation have severely limited their use and exploitation. Here we propose the development of two conceptually novel and general ways to prepare Nitrogen-centered radicals using visible light as sustainable and inexpensive source of energy. These processes will capitalize on recent developments in the host group that has disclosed the use of easy-to-make aryl oximes for the organocatalytic generation of iminyl radicals. This proposal seeks to substantially expand this visible light chemistry through the development of methods for the generation and use of any known Nitrogen-centered radical. The power of this approach will be demonstrated by the short synthesis of the complex molecule legionaminic acid, responsible for the spread of hospital-acquired infections. Furthermore, these methods will be integrated with other reaction platforms that, taking advantage of visible light as source of energy, will engage the Nitrogen-centered radical in new reactivity modes, to allow novel and powerful multicomponent reactions.
Through the use of this strategy, the rapid construction of many relevant and complex N-containing molecules will be possible. The development of such an innovative and ambitious project at the University of Manchester will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance my career development following the training plan envisioned.
|year||authors and title||journal||last update|
Alessandro Ruffoni, Fabio JuliÃ¡, Thomas D. Svejstrup, Alastair J. McMillan, James J. Douglas, Daniele Leonori
Practical and regioselective amination of arenes using alkyl amines
published pages: 426-433, ISSN: 1755-4330, DOI: 10.1038/s41557-019-0254-5
|Nature Chemistry 11/5||2019-10-14|
Daniel Fernandez Reina, Alessandro Ruffoni, Yasair S. S. Al-Faiyz, James J. Douglas, Nadeem S. Sheikh, Daniele Leonori
Visible-Light-Mediated Reactions of Electrophilic Radicals with Vinyl and Allyl Trifluoroborates
published pages: 4126-4130, ISSN: 2155-5435, DOI: 10.1021/acscatal.7b01120
|ACS Catalysis 7/6||2019-10-14|
Thomas D. Svejstrup, Alessandro Ruffoni, Fabio JuliÃ¡, Valentin M. Aubert, Daniele Leonori
Synthesis of Arylamines via Aminium Radicals
published pages: 14948-14952, ISSN: 1433-7851, DOI: 10.1002/anie.201708693
|Angewandte Chemie International Edition 56/47||2019-10-14|
David C. Marcote, Rosie Street-Jeakings, Elizabeth Dauncey, James J. Douglas, Alessandro Ruffoni, Daniele Leonori
Photoinduced decarboxylative azidation of cyclic amino acids
published pages: 1839-1842, ISSN: 1477-0520, DOI: 10.1039/c8ob02702a
|Organic & Biomolecular Chemistry 17/7||2019-10-14|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NCR" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "NCR" are provided by the European Opendata Portal: CORDIS opendata.
Contraception meets the environment: everyday contraceptive practices, politics, and futures in a toxic ageRead More
Retrospective genomic analyses of shortfin Mako shark (Isurus oxyrinchus) using DNA from archived jawsRead More
Focal volume Control Using Structured Illumination SourcesRead More