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Normothermic perfusion devices for renal and hepatic preservation and viability assessment

Total Cost €


EC-Contrib. €






Project "NORMOPERF" data sheet

The following table provides information about the project.


Organization address
address: AVENIDA DE MADRID 117 5 A
postcode: 50010
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-05-01   to  2016-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EBERS MEDICAL TECHNOLOGY SL ES (ZARAGOZA) coordinator 50˙000.00


 Project objective

Organ transplantation is the best available technique for the treatment of end-stage failure of most essential organs. However, the further development of transplantation is being hampered by the scarcity of available organs and the limitations of static cold preservation: lack of information about the organ function and viability, ischemia-reperfusion injury, short preservation times and poor compatibility with suboptimal organs.

Our solution to overcome these limitations consists in a portable medical device that is capable of maintaining the human kidney or liver in a viable state for sustained periods under physiological conditions ex vivo by means of a normothermic perfusion of the organ with a preservation solution that delivers oxygen, nutrients and chemical signals. Through maintaining the physiological cellular metabolism, it is possible to prolong the preservation times, reduce to a minimum ischemia-reperfusion injury, assess the organ viability and function by means of monitoring key parameters and increase the number of available organs.

Our envisaged final solution consists in a product with three elements: the perfusion machine and two single-use consumables: the perfusion circuit and the preservation solution. Specific versions of the consumables will be available for each organ type (liver or kidney), but all of them will be compatible with the same perfusion machine. The product will address a global market, focusing initially on the EU and in a second phase on the USA.

EBERS has a fully functional prototype of the device, validated and demonstrated using a porcine transplant model. In Phase 1 of the project, IP and regulatory strategies will be refined, the product concept will be validated, further market knowledge will be gained and the commercialisation plan will be detailed. In Phase 2, the prototype will be industrialised, a clinical assay will be performed and the device will receive CE-mark approval, becoming a market ready product.

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The information about "NORMOPERF" are provided by the European Opendata Portal: CORDIS opendata.

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