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Nyxoah

Ultra-small implanted neurostimulation device for the treatment of Obstructive Sleep Apnea

Total Cost €

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EC-Contrib. €

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Partnership

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 Nyxoah project word cloud

Explore the words cloud of the Nyxoah project. It provides you a very rough idea of what is the project "Nyxoah" about.

loop    clinical    ineffective    morbidity    security    obstructive    pressure    stroke    activation    neurostimulator    central    company    disorder    closed    drawbacks    patch    2009    cardiovascular    noisy    burnout    options    wirelessly    mask    plan    founded    tells    prevalent    tiny    keep    adjust    displays    mortality    disposable    implant    uncomfortable    annual    disruptive    impacts    neurostimulation    physicians    agencies    surgery    outright    continue    150b    disease    heart    nerve    regualatory    performance    smaller    depression    attached    fail    outcome    unpleasant    chronic    neurocognitive    responds    cloud    pulse    100m    economic    first    poor    standards    acute    cohorts    cpap    industrialization    device    monitoring    detects    health    powered    refuse    attack    stuck    therapeutic    obese    machine    constant    cardiac    communicates    chin    invasive    lifelong    treatment    worldwide    resistance    elderly    smart    apnea    50    daytime    patients    sleep    sleepiness    social    people    line    risk    world    synced    chip    implanted    implantations    trials    efficacy    public    nyxoah    feedback    infection    lower    arrhythmia    reimbursement    app    healthcare    patient    linked    compliance    tissue   

Project "Nyxoah" data sheet

The following table provides information about the project.

Coordinator
NYXOAH SA 

Organization address
address: RUE DU FOND CATTELAIN 2
city: MONT-SAINT-GUIBERT
postcode: 1435
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.4. (Active ageing and self-management of health)
2. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.3.1.6. (Health care provision and integrated care)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2016-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NYXOAH SA BE (MONT-SAINT-GUIBERT) coordinator 50˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Obstructive Sleep Apnea is the world's most common sleep disorder and affects 100m people worldwide. It is particularly prevalent among elderly and obese cohorts and is a lifelong disease, with acute and chronic health impacts. It is linked to increased cardiovascular morbidity and mortality, and associated with increased risk of heart attack, cardiac arrhythmia, stroke, daytime sleepiness, depression and poor neurocognitive performance. Estimated annual economic costs of the disease are €60-150b. Established therapeutic options are uncomfortable with unpleasant side effects and/or ineffective; they can also require invasive surgery. Compliance is a major problem with the first line treatment, CPAP: 50% of users refuse it outright or fail to continue use after 1 year. Nyxoah's disruptive neurostimulation device responds directly to these needs and drawbacks. Central to the system is a tiny device implanted under the chin that - compared to other neurostimulator implantations - is smaller, less invasive and has lower risk of infection. The device is powered wirelessly by an activation chip, which is attached to a disposable smart patch and stuck under the chin before sleep. No mask, no noisy machine, no unpleasant side effects. The chip has a closed feedback loop with the implant, which detects tissue resistance and tells the chip to adjust the pulse to keep constant pressure on the nerve, to avoid burnout; it also communicates wirelessly with an app, which displays useful information (synced with the cloud) for use by patients, physicians and social security agencies; this is a key development to allow treatment compliance monitoring and therefore for reimbursement. During the Phase 1 project, the company, founded in 2009, will assess scale-up industrialization plan, product development according to regualatory standards and clinical trials to be deployed in Europe to show the system efficacy on patient outcome and public healthcare costs.

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The information about "NYXOAH" are provided by the European Opendata Portal: CORDIS opendata.

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