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Translational and Transdisciplinary research in Modeling Infectious Diseases

Total Cost €


EC-Contrib. €






Project "TransMID" data sheet

The following table provides information about the project.


Organization address
postcode: 3500

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Project website
 Total cost 1˙639˙168 €
 EC max contribution 1˙639˙168 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-CoG
 Funding Scheme ERC-COG
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2021-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT HASSELT BE (HASSELT) coordinator 1˙203˙485.00
2    UNIVERSITEIT ANTWERPEN BE (ANTWERPEN) participant 435˙683.00


 Project objective

TransMID focuses on the development of novel methods to estimate key epidemiological parameters from both serological and social contact data, with the aim to significantly expand the range of public health questions that can be adequately addressed using such data. Using new statistical and mathematical theory and newly collected as well as readily available serological and social contact data (mainly from Europe), fundamental mathematical and epidemiological challenges as outlined in the following work packages will be addressed: (a) frequency and density dependent mass action relating potential effective contacts to transmission dynamics in (sub)populations of different sizes with an empirical assessment using readily available contact data, (b) behavioural and temporal variations in contact patterns and their impact on the dynamics of infectious diseases, (c) close contact household networks and the assumption of homogeneous mixing within households, (d) estimating parameters from multivariate and serial cross-sectional serological data taking temporal effects and heterogeneity in acquisition into account in combination with the use of social contact data, and (e) finally the design of sero- and social contact surveys with specific focus on serial cross-sectional surveys. TransMID is transdisciplinary in nature with applications on diseases of major public health interest, such as pertussis, cytomegalovirus and measles. Translational methodology is placed at the heart of TransMID resulting in the development of a unifying methodology for other diseases and settings. The development of a toolbox and accompanying software allow easy and effective application of these fundamentally improved techniques on many infectious diseases and in different geographic contexts, which should maximize TransMID’s impact on public health in Europe and beyond.


year authors and title journal last update
List of publications.
2018 Marc Aerts, Adelino JC Juga, Niel Hens
Measures for concordance and discordance with applications in disease control and prevention
published pages: 96228021879625, ISSN: 0962-2802, DOI: 10.1177/0962280218796252
Statistical Methods in Medical Research 2019-09-02
2019 Nina Keersmaekers, Benson Ogunjimi, Pierre Van Damme, Philippe Beutels, Niel Hens
An ODE-based mixed modelling approach for B- and T-cell dynamics induced by Varicella-Zoster Virus vaccines in adults shows higher T-cell proliferation with Shingrix than with Varilrix
published pages: 2537-2553, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2019.03.075
Vaccine 37/19 2019-09-02
2019 Diana M Hendrickx, Steven Abrams, Niel Hens
The impact of behavioral interventions on co-infection dynamics: An exploration of the effects of home isolation
published pages: 5-18, ISSN: 0022-5193, DOI: 10.1016/j.jtbi.2019.05.017
Journal of Theoretical Biology 476 2019-09-02
2018 Nele Goeyvaerts, Eva Santermans, Gail Potter, Andrea Torneri, Kim Van Kerckhove, Lander Willem, Marc Aerts, Philippe Beutels, Niel Hens
Household members do not contact each other at random: implications for infectious disease modelling
published pages: 20182201, ISSN: 0962-8452, DOI: 10.1098/rspb.2018.2201
Proceedings of the Royal Society B: Biological Sciences 285/1893 2019-09-02
2019 Thang Van Hoang, Pietro Coletti, Alessia Melegaro, Jacco Wallinga, Carlos G. Grijalva, John W. Edmunds, Philippe Beutels, Niel Hens
A Systematic Review of Social Contact Surveys to Inform Transmission Models of Close-contact Infections
published pages: 1, ISSN: 1044-3983, DOI: 10.1097/ede.0000000000001047
Epidemiology 2019-08-30
2018 Pietro Coletti, Chiara Poletto, Clément Turbelin, Thierry Blanchon, Vittoria Colizza
Shifting patterns of seasonal influenza epidemics
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-30949-x
Scientific Reports 8/1 2019-08-30
2019 Stéphanie Blaizot, Sereina A. Herzog, Steven Abrams, Heidi Theeten, Amber Litzroth, Niel Hens
Sample size calculation for estimating key epidemiological parameters using serological data and mathematical modelling
published pages: , ISSN: 1471-2288, DOI: 10.1186/s12874-019-0692-1
BMC Medical Research Methodology 19/1 2019-09-02

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The information about "TRANSMID" are provided by the European Opendata Portal: CORDIS opendata.

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