Opendata, web and dolomites

ventralHippocampus SIGNED

Neuronal circuits for emotions in the ventral CA1 hippocampus

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "ventralHippocampus" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAET BERN 

Organization address
address: HOCHSCHULSTRASSE 6
city: BERN
postcode: 3012
website: http://www.unibe.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website http://www.physio.unibe.ch/
 Total cost 1˙493˙736 €
 EC max contribution 1˙493˙736 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAET BERN CH (BERN) coordinator 1˙493˙736.00

Map

 Project objective

A fundamental objective in modern neurosciences is to understand the neural mechanisms of learning and memory in both healthy and pathological conditions. The hippocampus is a high-order cortical brain region important for emotions and cognition. The ventral subdivision of the hippocampus (anterior hippocampus in primates) is mostly involved in anxiety and contextual fear conditioning behaviours. Pyramidal cells of the CA1 region of the hippocampus represent a main hippocampal output to numerous brains regions relevant for emotional and cognitive processes. The activity and timing of these CA1 pyramidal cells are controlled by a set of very diverse long-range afferent inputs and by local GABAergic interneurons. However, the function of afferent pathways to- and of local GABAergic interneurons in the ventral CA1 hippocampus during contextual fear conditioning and anxiety behaviours have not been investigated so far. We hypothesise that distinct sub-circuits in the ventral CA1 hippocampus differentially contribute to emotional behaviours by diverse and complementary neuronal and network mechanisms. To test this hypothesis, we will use an innovative cross-level approach combining single-unit recordings of ventral CA1 GABAergic interneurons and of afferent brain regions to the ventral CA1 hippocampus, local field potential recordings, selective optogenetic strategies, cell-type-specific viral tracing, juxtacellular recording and labelling from ventral CA1 GABAergic interneurons, and behavioural paradigms in rodents. The originality of the proposal relies on identifying specific neuronal circuits and mechanisms in the ventral CA1 hippocampus to understand how normal and pathological brain function might arise at the behavioural level. Altogether, my research proposal aims at discovering logics of cortical computations during behaviour which may lead to translational applications for the clinics.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "VENTRALHIPPOCAMPUS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "VENTRALHIPPOCAMPUS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

PROGRESS (2019)

The Enemy of the Good: Towards a Theory of Moral Progress

Read More  

DISINTEGRATION (2019)

The Mass Politics of Disintegration

Read More  

EpigeneticScars (2020)

Understanding DSB repair from pathway choice to long term effects and their consequences.

Read More