Explore the words cloud of the ByAxon project. It provides you a very rough idea of what is the project "ByAxon" about.
The following table provides information about the project.
FUNDACION IMDEA NANOCIENCIA
|Coordinator Country||Spain [ES]|
|Total cost||3˙752˙057 €|
|EC max contribution||3˙752˙057 € (100%)|
1. H2020-EU.1.2.1. (FET Open)
|Duration (year-month-day)||from 2017-01-01 to 2020-12-31|
Take a look of project's partnership.
|1||FUNDACION IMDEA NANOCIENCIA||ES (MADRID)||coordinator||1˙212˙500.00|
|2||CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS||FR (PARIS)||participant||1˙161˙903.00|
|3||SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE||IT (TRIESTE)||participant||636˙960.00|
|4||Mfd-diagnostics GmbH||DE (Wendelsheim)||participant||287˙500.00|
|5||SERVICIO DE SALUD DE CASTILLA LA MANCHA||ES (TOLEDO)||participant||243˙569.00|
|6||AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS||ES (MADRID)||participant||209˙624.00|
ByAxon is devoted to the development of a new generation of sensors and electrodes based on nanotechnology materials for neural interfacing. We aim to design and build a prototype of an active implant that could work directly at the spinal cord (SC) level. This implant will be primary focused on restoring the transmission of electrical signals in the injured SC, acting as an active local bypass, something not possible with current technology. Further applications might include deep brain stimulation or retinal implants, among others. Current neural interfacing approaches are based on detecting electric potentials at the brain level, and/or triggering functional electrical stimulation (FES) through electrodes at muscular or SC levels. Important present drawbacks are the large number of cables and electrodes they require and, specially, the lack of sensory feedback. The ultimate non-contact sensing devices (magnetoencephalography) detect magnetic-field pulses generated by potentials at the brain, but require cryogenic temperatures, and, hence, are not portable. We will exploit here the enhanced properties of nanostructured materials to develop improved room temperature magnetoresistance-based high-resolution magnetic sensors. This will allow tackling not only the brain but also the SC directly. We pursuit a novel integrated interface comprising both sensing and stimulation at the SC level. To reach this aim, we will develop FES electrodes of enhanced adhesion and efficiency by using nanowire coatings. ByAxon is supported by an interdisciplinary consortium, going from material scientists and electronic experts to biologists and clinicians. Our nanotechnology-based approach offers a novel perspective and will be complementary to, but independent from, present neural regenerative techniques. Our technology promises significant outcomes towards the development of an active local bypass and it has the potential to provide much-needed breakthroughs in future neuromedicine.
|Dissemination and Exploitation Plan||Documents, reports||2019-06-06 16:04:37|
|Report on electrophysiological tests 2||Documents, reports||2019-06-06 16:04:30|
|Report on the magnetic sensor and nanostructured electrode development||Documents, reports||2019-05-24 11:49:59|
|Functional artificial neuron||Demonstrators, pilots, prototypes||2019-05-24 11:49:52|
|First nanostructured electrode||Demonstrators, pilots, prototypes||2019-05-24 11:49:54|
|Social network sites||Websites, patent fillings, videos etc.||2019-05-24 11:49:49|
|First four-bridge magnetic sensor||Demonstrators, pilots, prototypes||2019-05-24 11:49:53|
|Website and project logo||Websites, patent fillings, videos etc.||2019-05-24 11:50:01|
|First nanostructured electrode on neuron-accesible substrates||Demonstrators, pilots, prototypes||2019-05-24 11:49:59|
|Public report on biocompatibility in vitro 1||Documents, reports||2019-05-24 11:49:49|
Take a look to the deliverables list in detail: detailed list of ByAxon deliverables.
|year||authors and title||journal||last update|
Ankor GonzÃ¡lez-Mayorga, Elisa LÃ³pez-Dolado, MarÃa C. GutiÃ©rrez, Jorge E. Collazos-Castro, M. Luisa Ferrer, Francisco del Monte, MarÃa C. Serrano
Favorable Biological Responses of Neural Cells and Tissue Interacting with Graphene Oxide Microfibers
published pages: 8253-8263, ISSN: 2470-1343, DOI: 10.1021/acsomega.7b01354
|ACS Omega 2/11||2019-06-11|
Olivier Rousseau, StÃ©phane Flament, Bruno Guillet, Marc Lam Chok Sing, Laurence MÃ©chin
Magnetic Sensors Based on AMR Effect in LSMO Thin Films
published pages: 635, ISSN: 2504-3900, DOI: 10.3390/proceedings1040635
Emily R. Aurand, Sadaf Usmani, Manuela Medelin, Denis Scaini, Susanna Bosi, Federica B. Rosselli, Sandro Donato, Giuliana Tromba, Maurizio Prato, Laura Ballerini
Nanostructures to Engineer 3D Neural-Interfaces: Directing Axonal Navigation toward Successful Bridging of Spinal Segments
published pages: 1700550, ISSN: 1616-301X, DOI: 10.1002/adfm.201700550
|Advanced Functional Materials 28/12||2019-06-11|
Paolo Perna, Davide Maccariello, Fernando Ajejas, Ruben Guerrero, Laurence MÃ©chin, Stephane Flament, Jacobo Santamaria, Rodolfo Miranda, Julio Camarero
Engineering Large Anisotropic Magnetoresistance in La 0.7 Sr 0.3 MnO 3 Films at Room Temperature
published pages: 1700664, ISSN: 1616-301X, DOI: 10.1002/adfm.201700664
|Advanced Functional Materials 27/26||2019-06-11|
Sandeep Kumar Chaluvadi, Fernando Ajejas, Pasquale Orgiani, Olivier Rousseau, Giovanni Vinai, Aleksandr Yu Petrov, Piero Torelli, Alain Pautrat, Julio Camarero, Paolo Perna, Laurence Mechin
Room temperature biaxial magnetic anisotropy in La 0.67 Sr 0.33 MnO 3 thin films on SrTiO 3 buffered MgO (001) substrates for spintronic applications
published pages: 52403, ISSN: 0003-6951, DOI: 10.1063/1.5020072
|Applied Physics Letters 113/5||2019-05-15|
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