Opendata, web and dolomites

iMDx SIGNED

Microfiber Electrofluidics for Integrated Molecular Diagnostics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 iMDx project word cloud

Explore the words cloud of the iMDx project. It provides you a very rough idea of what is the project "iMDx" about.

powerful    detect    techniques    sequence    mefs    textiles    microelectronics    hiv    portable    paper    pcr    3d    cells    diagnostics    handling    broaden    lpa    rna    nasba    indirect    assay    protein    samples    lamp    measuring    electrochemical    acid    ligation    monolithically    sheets    automated    amplified    biomolecules    disposable    resistant    dna    point    diagnosis    combined    diseases    manipulation    almost    rely    diagnostic    clinical    centralized    rpa    inappropriate    microfluidics    outcome    structure    fabrication    instruments    materials    mef    bacteria    pricing    antibody    applicability    specialized    amplifications    reagents    detection    proteins    breaking    ground    dramatically    skilled    imdx    of    time    electrofluidics    porous    amplification    zero    ebola    translation    proximity    microfiber    laboratories    times    realizing    accessibility    platform    nucleic    broad    readily    storage    integrate    molecular    antibiotic    exist    basically    care    biomedical   

Project "iMDx" data sheet

The following table provides information about the project.

Coordinator
KUNGLIGA TEKNISKA HOEGSKOLAN 

Organization address
address: BRINELLVAGEN 8
city: STOCKHOLM
postcode: 100 44
website: www.kth.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 1˙499˙180 €
 EC max contribution 1˙499˙180 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-08-01   to  2022-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KUNGLIGA TEKNISKA HOEGSKOLAN SE (STOCKHOLM) coordinator 1˙499˙180.00

Map

 Project objective

'Diagnosis of an increasing number of diseases (such as HIV, Ebola and antibiotic resistant bacteria) rely on centralized laboratories with specialized instruments and skilled personnel. This type of clinical analysis with long lead times and high cost is inappropriate for point of care diagnostics. Portable, automated, and disposable devices with integrated molecular diagnostics (iMDx), could solve this problem. Such devices, however, basically do not exist today.

This research program will develop materials, methods, and diagnostic techniques to enable portable integrated molecular diagnostics (iMDx) devices, that are disposable (almost zero-cost), and that can detect a broad range of diseases using DNA amplification. To achieve this, we will develop '3D microfiber electrofluidics (MEF)'. MEFs rely on simple and readily available porous sheets including paper, and textiles. Their fabrication is simple, and yet they are very powerful because they can monolithically integrate 3D microfluidics, 3D microelectronics, electrochemical analysis, storage of reagents / biomolecules, as well as handling and manipulation of cells.

We will develop techniques, using the combined capabilities of MEFs, for real-time DNA amplification and electrochemical DNA detection directly from samples. We will use three amplifications techniques for realizing a comprehensive iMDx platform: i) DNA detection, using established and state of the art amplification methods (e.g. PCR, LAMP, RPA). ii) RNA detection, using 'nucleic acid sequence-based amplification' (NASBA). iii) Protein detection, using antibody to DNA translation through 'proximity ligation assay' LPA, and using the detection of the amplified DNA is the indirect measure of proteins.

The outcome of this program has the potential to be ground breaking, and change the structure of measuring, processing, and pricing of biomedical information, and dramatically broaden its accessibility and applicability. '

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IMDX" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "IMDX" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

AST (2019)

Automatic System Testing

Read More  

ERC VP CSA (2018)

Support to the Vice-Presidents of the ERC Scientific Council 2018

Read More  

CURVE-X (2019)

Industrialisation of curved sensors and related imagers

Read More