Opendata, web and dolomites

iMDx SIGNED

Microfiber Electrofluidics for Integrated Molecular Diagnostics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 iMDx project word cloud

Explore the words cloud of the iMDx project. It provides you a very rough idea of what is the project "iMDx" about.

dna    specialized    resistant    proteins    platform    diagnosis    care    electrofluidics    point    cells    antibody    amplification    pcr    automated    readily    ebola    combined    laboratories    amplified    imdx    hiv    amplifications    samples    diagnostic    outcome    detect    zero    reagents    sequence    times    biomolecules    detection    antibiotic    manipulation    basically    realizing    applicability    electrochemical    powerful    rna    protein    dramatically    mefs    ligation    bacteria    lpa    accessibility    integrate    translation    lamp    skilled    indirect    almost    rpa    3d    microfiber    acid    broaden    techniques    paper    exist    broad    proximity    clinical    microelectronics    pricing    handling    measuring    ground    of    molecular    rely    inappropriate    porous    assay    centralized    diagnostics    instruments    fabrication    materials    nasba    time    sheets    disposable    storage    monolithically    portable    microfluidics    diseases    mef    nucleic    structure    breaking    textiles    biomedical   

Project "iMDx" data sheet

The following table provides information about the project.

Coordinator
KUNGLIGA TEKNISKA HOEGSKOLAN 

Organization address
address: BRINELLVAGEN 8
city: STOCKHOLM
postcode: 100 44
website: www.kth.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 1˙499˙180 €
 EC max contribution 1˙499˙180 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-08-01   to  2022-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KUNGLIGA TEKNISKA HOEGSKOLAN SE (STOCKHOLM) coordinator 1˙499˙180.00

Map

 Project objective

'Diagnosis of an increasing number of diseases (such as HIV, Ebola and antibiotic resistant bacteria) rely on centralized laboratories with specialized instruments and skilled personnel. This type of clinical analysis with long lead times and high cost is inappropriate for point of care diagnostics. Portable, automated, and disposable devices with integrated molecular diagnostics (iMDx), could solve this problem. Such devices, however, basically do not exist today.

This research program will develop materials, methods, and diagnostic techniques to enable portable integrated molecular diagnostics (iMDx) devices, that are disposable (almost zero-cost), and that can detect a broad range of diseases using DNA amplification. To achieve this, we will develop '3D microfiber electrofluidics (MEF)'. MEFs rely on simple and readily available porous sheets including paper, and textiles. Their fabrication is simple, and yet they are very powerful because they can monolithically integrate 3D microfluidics, 3D microelectronics, electrochemical analysis, storage of reagents / biomolecules, as well as handling and manipulation of cells.

We will develop techniques, using the combined capabilities of MEFs, for real-time DNA amplification and electrochemical DNA detection directly from samples. We will use three amplifications techniques for realizing a comprehensive iMDx platform: i) DNA detection, using established and state of the art amplification methods (e.g. PCR, LAMP, RPA). ii) RNA detection, using 'nucleic acid sequence-based amplification' (NASBA). iii) Protein detection, using antibody to DNA translation through 'proximity ligation assay' LPA, and using the detection of the amplified DNA is the indirect measure of proteins.

The outcome of this program has the potential to be ground breaking, and change the structure of measuring, processing, and pricing of biomedical information, and dramatically broaden its accessibility and applicability. '

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IMDX" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "IMDX" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ENTRAPMENT (2019)

Septins: from bacterial entrapment to cellular immunity

Read More  

inSight (2019)

Moving a novel gene therapy paradigm to treat blindness to the market

Read More  

SLAMseq (2019)

SLAMseq: Temporal resolution in gene expression profiling across multiple platforms

Read More