Opendata, web and dolomites

DrugSearchTool SIGNED

Innovative FRET-based toolkit for screening of drugs to fight miRNA-related diseases and its use in the development of cancer treatment with miRNA-96 as a therapeutic target

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DrugSearchTool project word cloud

Explore the words cloud of the DrugSearchTool project. It provides you a very rough idea of what is the project "DrugSearchTool" about.

fellowship    base    me    characterization    regarding    acid    cancer    biochemistry    analogues    advantage    reaching    mentoring    presentation    small    fret    intersectoral    molecules    networking    ouml    molecule    max    writing    industry    chalmers    outcome    pharmaceutical    96    rna    ugot    critical    structure    supervision    microrna    expertise    screening    fluorescent    free    interdisciplinary    marcus    roles    ttingen    skills    gothenburg    scientific    group    planck    universal    tumor    resolution    vitro    secondments    pancreatic    interaction    photophysical    assay    toolkit    communication    prof    utilized    invaluable    capacities    professional    astrazeneca    carry    postdoctoral    cells    urgent    cell    assays    master    gain    drugs    optimized    position    dynamics    university    globe    training    mirna    az    pioneered    maturity    interactions    suppressing    competences    wilhelmsson    fbas    throughput    warsaw    supervisor    starting    mirnas    full    apart    msca    biological    industrial    technique    nature    stated    nucleic   

Project "DrugSearchTool" data sheet

The following table provides information about the project.

Coordinator
CHALMERS TEKNISKA HOEGSKOLA AB 

Organization address
address: -
city: GOETEBORG
postcode: 41296
website: www.chalmers.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 185˙857 €
 EC max contribution 185˙857 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHALMERS TEKNISKA HOEGSKOLA AB SE (GOETEBORG) coordinator 185˙857.00

Map

 Project objective

The overall goal of this project is to develop a universal FRET-based toolkit for screening of drugs targeting microRNA (miRNA). Specific outcome will be a high-throughput assay for finding drugs targeting miRNA-96, a tumor-suppressing miRNA in pancreatic cancer cells. FRET is the technique of choice and recently, Prof. Marcus Wilhelmsson, Chalmers University of Technology (CHALMERS; project main supervisor) pioneered the development and photophysical characterization of fluorescent base analogues (FBAs) optimized for high-resolution FRET analysis of nucleic acid systems. There is an urgent need in pharmaceutical industry for an in vitro, cell-free, pre-miRNA-small molecule interaction high-throughput assay and also to increase the understanding of the nature of miRNAs. In this project, the unique FRET FBAs will be utilized to develop such assays and to provide new knowledge regarding miRNA structure, dynamics and interactions with other biological molecules or drugs. Apart from taking on the new research field stated above and developing my professional skills, I will bring in new competences to CHALMERS in RNA biochemistry (from the University of Warsaw and Max Planck Institute in Göttingen). Moreover, as part of my training, I will carry out research at AstraZeneca (AZ) and Gothenburg University (UGOT) through secondments. CHALMERS/AZ/UGOT have an established collaboration and I will take full advantage of their R&T capacities in order to gain interdisciplinary and intersectoral expertise as well as to master my skills in scientific communication, scientific writing, coordinating research projects, results exploitation, critical assessment, mentoring, supervision, presentation and networking with other researchers across the globe. This MSCA Postdoctoral Fellowship will help me reaching a position of professional maturity invaluable for starting up my own research group or taking leading roles in industrial R&D organizations.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DRUGSEARCHTOOL" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DRUGSEARCHTOOL" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

MultiSeaSpace (2019)

Developing a unified spatial modelling strategy that accounts for interactions between species at different marine trophic levels, and different types of survey data.

Read More  

AMPLE (2019)

A Study of the Notion of Ampleness in Model Theory and Tits Buildings

Read More  

LIGHTMATT-EXPLORER (2019)

Experimental determination of the paraxial-vectorial limit of light-matter interactions

Read More