Explore the words cloud of the Debrasa project. It provides you a very rough idea of what is the project "Debrasa" about.
The following table provides information about the project.
UNIVERSITE DE GENEVE
|Coordinator Country||Switzerland [CH]|
|Total cost||187˙419 €|
|EC max contribution||187˙419 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-05-01 to 2019-04-30|
Take a look of project's partnership.
|1||UNIVERSITE DE GENEVE||CH (GENEVE)||coordinator||187˙419.00|
Objective: The overarching goal of proposed project is to provide necessary knowledge about neurobiology of Major Depression Disorder (MDD), which would lead to higher efficacy in treatment of this affective disorder. The research objectives of the action are 1) identification of electrophysiological biomarkers of functional brain abnormities in treatment resistant depression (TRD) and 2) suggestion of novel targets for neurostimulation in patients with TRD. Methods: Twenty patients with major Depression Disorder (MDD) and 20 healthy controls will undergo a resting-state high-density EEG recording (HD-EEG). Microstate analysis will be performed to identify possible biomarkers of functional brain abnormity in MDD. Source activity will be obtained for regions of interest (ROI) using individual head model and a distributed linear inverse solution. Directed functional connectivity using Granger causal modelling will be applied to the source signals of ROI to identify abnormally interconnected nodes. Relevance: If new biomarkers of functional brain abnormity in MDD are identified, better characterisation of pathophysiology of depression will be made. If abnormal nodes of large-scale brain neuronal network are identified, new and individually specific targets for deep brain stimulation (DBS) will be suggested. These findings will support future implementation of highly individualised DBS treatment of TRD.
|year||authors and title||journal||last update|
Alena DamborskÃ¡, EliÅ¡ka HonzÃrkovÃ¡, Richard BarteÄek, Jana HoÅ™ÃnkovÃ¡, Sylvie FedorovÃ¡, Å imon OndruÅ¡, Christoph M. Michel, Maria Rubega
Altered directed functional connectivity of the right amygdala in depression: high-density EEG study
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-020-61264-z
|Scientific Reports 10/1||2020-03-24|
Alena DamborskÃ¡, Camille Piguet, Jean-Michel Aubry, Alexandre G. Dayer, Christoph M. Michel, Cristina Berchio
Altered Electroencephalographic Resting-State Large-Scale Brain Network Dynamics in Euthymic Bipolar Disorder Patients
published pages: , ISSN: 1664-0640, DOI: 10.3389/fpsyt.2019.00826
|Frontiers in Psychiatry 10||2019-11-22|
Dominik Drobisz, Alena DamborskÃ¡
Deep brain stimulation targets for treating depression
published pages: 266-273, ISSN: 0166-4328, DOI: 10.1016/j.bbr.2018.11.004
|Behavioural Brain Research 359||2019-09-25|
Alena DamborskÃ¡, Miralena I. Tomescu, EliÅ¡ka HonzÃrkovÃ¡, Richard BarteÄek, Jana HoÅ™ÃnkovÃ¡, Sylvie FedorovÃ¡, Å imon OndruÅ¡, Christoph M. Michel
EEG Resting-State Large-Scale Brain Network Dynamics Are Related to Depressive Symptoms
published pages: , ISSN: 1664-0640, DOI: 10.3389/fpsyt.2019.00548
|Frontiers in Psychiatry 10||2019-09-25|
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The information about "DEBRASA" are provided by the European Opendata Portal: CORDIS opendata.
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