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Exploring dry storage as an alternative biobanking strategy inspired by Nature

Total Cost €


EC-Contrib. €






 DRYSTORE project word cloud

Explore the words cloud of the DRYSTORE project. It provides you a very rough idea of what is the project "DRYSTORE" about.

scientific    public    laboratory    audiences    elucidate    mentoring    stability    learning    mammalian    genomic    crossing    cell    continuous    fast    trained    alternatives    date    somatic    supply    nature    sperm    outcomes    independent    stakeholders    genome    epi    competitive    protocol    combining    fibroblast    load    latest    function    creative    global    biobanking    host    scientists    expert    technologies    scientist    dna    searching    cryobiology    perfect    expensive    expertise    satisfactory    ln    advantage    mutual    stepping    attractive    protect    policymakers    transfer    participating    preservation    scnt    carbon    definitive    drawbacks    facilities    researcher    efficiency    footprint    students    data    maintained    structure    creates    biology    background    techniques    nuclear    genetic    freezing    solid    communication    epigenetic    benefit    stone    survive    profile    nitrogen    supervisor    monitoring    interdisciplinary    model    communicating    skills    desiccation    liquid    discovery    drying    andrology    cells    conferences    industry    embryology   

Project "DRYSTORE" data sheet

The following table provides information about the project.


Organization address
address: VIA RENATO BALZARINI 1 3 5 7
city: TERAMO
postcode: 64100

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website
 Total cost 180˙277 €
 EC max contribution 180˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TERAMO IT (TERAMO) coordinator 180˙277.00


 Project objective

Biobanking under liquid nitrogen (LN) has satisfactory efficiency but it comes with many drawbacks (e.g. expensive, high carbon footprint, need dedicated facilities, trained personnel, and continuous monitoring and LN supply). Searching Nature for alternatives, long-term preservation there is done by drying rather than freezing. To date, however, mammalian cells do not survive the drying process. Even so, if somatic cells genetic and epigenetic load is maintained, drying can find an important role in biobanking, a fast growing global industry. We aim to elucidate the effects of drying on DNA structure and function, crucial aspects of long-term biobanking not investigated yet, using fibroblast as a model cell, and combining advanced freezing and drying techniques with state-of-the-art Somatic Cell Nuclear Transfer (SCNT) and latest genomic technologies. The expected outcomes are definitive data on effects of drying on genomic stability/function, and possible discovery of a protocol to protect the epi/genetic load during cell drying. The crossing between the Researcher’s scientific interest and experience in sperm biology, andrology, cryobiology and drying and the Supervisor’s expertise in embryology and SCNT creates an attractive and very solid background for this proposal, with mutual benefit to both Host and Researcher. While strengthening the Supervisor’s laboratory with his expertise, the Researcher will enhance his creative potential and further develop his interdisciplinary and communication skills by learning SCNT and whole genome analysis as well as mentoring students, participating in conferences, and communicating research results to targeted audiences (scientists, general public, students, stakeholders, policymakers), thus enhancing his scientific profile. This proposal is the perfect stepping stone for the Researcher to become an independent scientist and an expert in desiccation for biobanking, while contributing a competitive advantage to the Host.


year authors and title journal last update
List of publications.
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-27
2019 Joseph Saragusty, Pasqualino Loi
Exploring dry storage as an alternative biobanking strategy inspired by Nature
published pages: 17-27, ISSN: 0093-691X, DOI: 10.1016/j.theriogenology.2018.11.027
Theriogenology 126 2020-01-27

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