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ADOC SIGNED

Characterization and monitoring of vigilance fluctuation in disorders of consciousness

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

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Project "ADOC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE DE LIEGE 

Organization address
address: PLACE DU 20 AOUT 7
city: LIEGE
postcode: 4000
website: www.ulg.ac.be

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Project website http://www.gigacoma.uliege.be/cms/c_4255887/fr/portail-gigacoma
 Total cost 160˙800 €
 EC max contribution 160˙800 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-08-01   to  2019-11-10

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE LIEGE BE (LIEGE) coordinator 160˙800.00

Map

 Project objective

This prospective exploratory study will aim at characterizing vigilance fluctuation in patients with disorders of consciousness (as defined by a change in diurnal behavioral response over time) using neurophysiological parameters. We based this project on the assumption that changes at the Coma Recovery Scale-Revised scores (i.e., behavioral responsiveness) will be associated with a change in ocular measures and EEG complexity, suggesting that some of these parameters could be used for monitoring vigilance in this population. We expect that this fluctuation will be particularly marked in patients with a minimally conscious state as compared with patients in an unresponsive wakefulness syndrome who will display a more stable pattern of response over the two days. This project aims to better understand the course of vigilance fluctuation in DOC and to develop an objective tool based on biomarkers that could be used at bedside to determine the best periods to assess and treat these patients.

 Publications

year authors and title journal last update
List of publications.
2018 Chatelle C, Thibaut A, Gosseries O, Cassol H, Aubinet C, Carrière M, Wolff A, Martens G, Barra A, Martial C, Blandiaux S, Wannez S, Charland-Verville V, Laureys S.
Fluctuation in behavioral responsiveness in severely brain-injured patients
published pages: 90–276, ISSN: 1351-5101, DOI:
European Journal of Neurology 25 2020-04-09
2019 Mortaheb S, Bonin E, Laureys S, Chatelle C.
Pupil diameter and Behavioral Responsiveness in Disorders of Consciousness
published pages: (Suppl. 33) 189-, ISSN: , DOI:
Brain Injury 2020-04-09

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The information about "ADOC" are provided by the European Opendata Portal: CORDIS opendata.

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