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iHEAR SIGNED

Investigating the meanings and mechanisms of psychotic experiences in young people: a novel, mixed-methods approach

Total Cost €

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EC-Contrib. €

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Partnership

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Project "iHEAR" data sheet

The following table provides information about the project.

Coordinator
ROYAL COLLEGE OF SURGEONS IN IRELAND 

Organization address
address: Saint Stephen's Green 123
city: DUBLIN
postcode: 2
website: www.rcsi.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website https://twitter.com/ihearstudy
 Total cost 1˙781˙622 €
 EC max contribution 1˙781˙622 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-COG
 Funding Scheme ERC-COG
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ROYAL COLLEGE OF SURGEONS IN IRELAND IE (DUBLIN) coordinator 1˙781˙622.00

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 Project objective

Up to one fifth of young people have had the experience of psychotic symptoms, such as hearing voices when there is no-one around, or seeing visions. We now know that young people who experience these symptoms are at increased risk of developing psychotic disorders in adulthood. We also know that these young people are at higher risk of a range of co-morbid disorders such as depression and anxiety, and particularly suicidal behaviours. On the other hand, many of these young people will remain well and, for them, the psychotic experiences were merely a transitory phenomenon.

Childhood trauma is known to be associated with increased risk for psychotic symptoms and is a promising target for intervention. However we do not yet know enough about what types or timing of stressors are involved in the pathogenesis of psychotic symptoms, nor the mechanism by which early life stress may lead to changes in brain structure and function resulting in symptoms such as hallucinations. We also need to be able to identify those young people who will benefit most from intervention.

This ground-breaking, multi-disciplinary programme of work sets out to address these issues by drawing together epidemiology, social science, anthropology and neuroscience to devise a comprehensive programme of work examining the relationship between early life stress and psychotic symptoms among young people.

Designed as three inter-related work packages, this iHEAR programme will exploit a large population-based cohort and will capitalise on my existing unique cohort of young people, who were known to have experienced psychotic symptoms in childhood, as they enter young adulthood. This iHEAR programme will result in new information which will allow the development of innovative interventions to prevent or pre-empt severe mental illness in later life.

 Publications

year authors and title journal last update
List of publications.
2020 Annette Burns, Helen Coughlan, Mary Cannon
Inconsistent trauma reporting is associated with emotional and behavioural problems and psychotic experiences in young people
published pages: , ISSN: 1471-244X, DOI: 10.1186/s12888-020-2438-3
BMC Psychiatry 20/1 2020-02-13
2020 Elaine M. McMahon, Paul Corcoran, Helen Keeley, Mary Clarke, Helen Coughlan, Danuta Wasserman, Christina W. Hoven, Vladimir Carli, Marco Sarchiapone, Colm Healy, Mary Cannon
Risk and protective factors for psychotic experiences in adolescence: a population-based study
published pages: 1-9, ISSN: 0033-2917, DOI: 10.1017/s0033291719004136
Psychological Medicine 2020-02-13
2019 Colm Healy, Helen Coughlan, James Williams, Mary Clarke, Ian Kelleher, Mary Cannon
Changes in self‐concept and risk of psychotic experiences in adolescence: a longitudinal population‐based cohort study
published pages: 1164-1173, ISSN: 0021-9630, DOI: 10.1111/jcpp.13022
Journal of Child Psychology and Psychiatry 60/11 2019-11-26
2019 Helen Coughlan, Colm Healy, Áine Ní Sheaghdha, Gareth Murray, Niamh Humphries, Mary Clarke, Mary Cannon
Early risk and protective factors and young adult outcomes in a longitudinal sample of young people with a history of psychotic‐like experiences
published pages: 1-14, ISSN: 1751-7885, DOI: 10.1111/eip.12855
Early Intervention in Psychiatry 2019 2019-09-13
2019 Niamh Dhondt, Colm Healy, Mary Clarke, Mary Cannon
Childhood adversity and adolescent psychopathology: evidence for mediation in a national longitudinal cohort study
published pages: 559-564, ISSN: 0007-1250, DOI: 10.1192/bjp.2019.108
British Journal of Psychiatry 215/3 2019-09-13
2018 Ana Calvo, Erik O’Hanlon, Helen Coughlan, Ian Kelleher, Mary Clarke, Mary Cannon
O6.1. HIPPOCAMPAL VOLUME IN ADOLESCENTS WITH PERSISTENT PSYCHOTIC EXPERIENCES: A LONGITUDINAL POPULATION-BASED MRI STUDY
published pages: S89-S89, ISSN: 0586-7614, DOI: 10.1093/schbul/sby015.222
Schizophrenia Bulletin 44/suppl_1 2019-09-13
2019 Colm Healy, Ross Brannigan, Niamh Dooley, Helen Coughlan, Mary Clarke, Ian Kelleher, Mary Cannon
Childhood and adolescent psychotic experiences and risk of mental disorder: a systematic review and meta-analysis
published pages: 1589-1599, ISSN: 0033-2917, DOI: 10.1017/s0033291719000485
Psychological Medicine 49/10 2019-09-13
2018 Eleanor Carey, Niamh Dooley, Diane Gillan, Colm Healy, Helen Coughlan, Mary Clarke, Ian Kelleher, Mary Cannon
Fine motor skill and processing speed deficits in young people with psychotic experiences: A longitudinal study
published pages: , ISSN: 0920-9964, DOI: 10.1016/j.schres.2018.08.014
Schizophrenia Research 2019-03-12
2018 Joanne Kenney, Ian Kelleher, Colm Healy, Niamh Dooley, Eleanor Carey, Amy Adair, Donal Campbell, Helen Coughlan, Erik O’ Hanlon, Mary Cannon
T83. PROCESSING SPEED PERFORMANCE AND FUNCTIONING IN YOUNG ADOLESCENTS EXPERIENCING AUDITORY HALLUCINATIONS
published pages: S147-S147, ISSN: 0586-7614, DOI: 10.1093/schbul/sby016.359
Schizophrenia Bulletin 44/suppl_1 2019-02-26
2018 Colm Healy, Mary Clarke, Ian Kelleher, Mary Cannon
O12.2. STICKS AND STONES MAY BREAK MY BONES BUT WORDS INCREASE THE RISK OF PSYCHOTIC EXPERIENCES
published pages: S109-S110, ISSN: 0586-7614, DOI: 10.1093/schbul/sby015.270
Schizophrenia Bulletin 44/suppl_1 2019-02-26
2018 C. Healy, D. Campbell, H. Coughlan, M. Clarke, I. Kelleher, M. Cannon
Childhood psychotic experiences are associated with poorer global functioning throughout adolescence and into early adulthood
published pages: 26-34, ISSN: 0001-690X, DOI: 10.1111/acps.12907
Acta Psychiatrica Scandinavica 138/1 2019-02-26
2018 Colm Healy, Aoife A. Gordon, Helen Coughlan, Mary Clarke, Ian Kelleher, Mary Cannon
Do childhood psychotic experiences improve the prediction of adolescent psychopathology? A longitudinal population-based study
published pages: , ISSN: 1751-7885, DOI: 10.1111/eip.12762
Early Intervention in Psychiatry 2019-02-26

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