Opendata, web and dolomites

H2020 projects about "pathogenesis"

The page lists 195 projects related to the topic "pathogenesis".

# achronym  title  year 
1 ParaFishControl Advanced Tools and Research Strategies for Parasite Control in European farmed fish 2015
2 CARBALIVE Clinical evaluation of carbons of controlled porosity as a new therapeutic for the treatment of liver cirrhosis and non-alcoholic fatty liver disease. 2015
3 PROPAG-AGEING The continuum between healthy ageing and idiopathic Parkinson Disease within a propagation perspective of inflammation and damage: the search for new diagnostic, prognostic and therapeutic targets 2015
4 PredicTOOL Nanomethods to understand what makes an endogenous protein immunogenic 2015
5 ApoptoMDS Hematopoietic stem cell Apoptosis in bone marrow failure and MyeloDysplastic Syndromes: Friend or foe? 2015
6 SILENCE Mechanisms of Gene Silencing by the Glucocorticoid Receptor 2015
7 FLDcure A potent Micro-RNA therapeutic for nonalcoholic fatty liver disease (NAFLD) 2015
8 SOS Sorting of Self 2015
9 CLOSPORE UNDERSTANDING THE CLOSTRIDIUM SPORE, A PREREQUISTE FOR DISEASE INTERVENTIONS AND EXPLOITATION 2015
10 Brain Metastases The Role of Circulating Monocytes in the Development of Brain Metastases 2015
11 Inflammafish Cross-talk between inflammation and autophagy in tuberculosis 2016
12 mini-liver SCCS Human “mini-liver” stem cell culture systems: from mechanisms behind liver cancer origin and recurrence to new therapeutic treatments 2016
13 KSHV QTV Identification of novel KSHV immune evasion mechanisms using a quantitative temporal viromics analysis 2015
14 INSCAPE Imaging Voltage Gated Sodium Channels Using Positron Emission Tomography 2015
15 BURK-6 Investigation of the Type VI secretion system-associated toxins of Burkholderia thailandensis 2015
16 RECOLOR Regulation and consequences of LRRK2 phosphorylation,a path to Parkinson’s disease therapy and diagnostics 2015
17 BactoDrug The Bacteroides dual-pumping membrane-integral pyrophosphatase: a novel drug target 2015
18 Athero MPh proliferation Macrophage proliferation and ontogeny in murine models of atherosclerosis 2016
19 HBV1 Innate immune responses to human hepatotropic viral infections 2015
20 FAtoUnFRAGILITY Fanconi anemia : a disease model to understand causes and consequences of common fragile site instability. 2015
21 C9ND C9orf72-mediated neurodegeneration: mechanisms and therapeutics 2015
22 OPTIMALZ Optical imaging of ocular pathology in Alzheimer’s disease 2015
23 DevoTed_miR MicroRNA determinants of the balance between effector and regulatory T cells in vivo 2015
24 RENOIR RENal prOgenItoRs as tools to understand kidney pathophysiology and treat kidney disorders 2015
25 BIOCONT6SS Inter-bacterial competition mediated by the type VI secretion system (T6SS): promising role in the biocontrol properties of Pseudomonas putida 2016
26 PRIISM-HD Pathways Regulating Intramyocellular Insulin Sensitivity and Metabolism in Health and Disease 2016
27 OxygenSensing Molecular mechanisms of acute oxygen sensing. 2015
28 LeukoTheranostics Harnessing Targeted Nanotheranostics to Reprogram Activated Leukocytes in Inflammatory Bowel Disease 2015
29 HEPCIR Cell circuits as targets and biomarkers for liver disease and cancer prevention 2016
30 NutrientSensingVivo The Physiology of Nutrient Sensing by mTOR 2016
31 M-Imm Novel etiology of autoimmune disorders: the role of acquired somatic mutations in lymphoid cells 2015
32 RUBICON Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders 2016
33 SWEETOOLS Smart Biologics: Developing New Tools in Glycobiology 2016
34 PREG-LAB Distinctive characterization of regulatory plasma cells and pro-inflammatory B cells in immunity: their origins, molecular properties, and cellular fates. 2016
35 HEP-CAR Mechanisms underlying hepatocellular carcinoma pathogenesis and impact of co-morbidities. 2016
36 CoSTREAM Common mechanisms and pathways in Stroke and Alzheimer's disease. 2015
37 VIVALDI Preventing and mitigating farmed bivalve diseases 2016
38 GvHDCure Understanding the dynamics of the immune system to cure graft-versus-host disease (GvHD). 2016
39 ESA -ITN European Sepsis Academy: towards new biomarkers to improve sepsis management 2016
40 DISSection Doctoral Industrial School on Human Skin models for Staphylococcal infections 2016
41 CaNANObinoids From Peripheralized to Cell- and Organelle-Targeted Medicine: The 3rd Generation of Cannabinoid-1 Receptor Antagonists for the Treatment of Chronic Kidney Disease 2016
42 NEUTRO-LILR Leukocyte immunoglobulin-like receptors (LILRs) on neutrophils 2016
43 IFNBetaMito Role of IFN-β in mitochondrial homeostasis and impact on Parkinson Disease 2016
44 a-Sign Cyclic nucleotide signalling in the human pathogen Listeria monocytogenes 2016
45 Prionomics Systematic profiling of molecular changes during prion disease progression 2016
46 EBOPATH Evaluation of species-specific ebolavirus pathophysiology in xenochimeric mice 2016
47 METAFORA Miniaturised Metabolomics Platform for Microvascular Research 2016
48 ChondUb Identification and characterisation of novel WWP2 substrates and their role in chondrogenesis and osteoarthritis 2016
49 EpiHope Epigenetic biomarkers for prediction of vascular complications and response to treatment in subjects with diabetes 2016
50 REGDAM REGULATORY T CELLS AND TISSUE DAMAGE CONTROL 2017
51 Ubl-Code Revealing the ubiquitin and ubiquitin-like modification landscape in health and disease 2016
52 CentSatRegFunc Dissecting the function and regulation of centriolar satellites: key regulators of the centrosome/cilium complex 2016
53 BoneMalar Mechanisms of bone marrow sequestration during malaria infection 2016
54 PANDORA Platelets: at the nexus of brain aneurysm 2016
55 PIGYVAX Making a yeast-based candidate vaccine against Porcine Epidemic Diarrhea Virus (PEDV) 2016
56 IMCIS Individualised medicine in chronic inflammatory skin diseases 2016
57 ToxoPersist Molecular Basis of Toxoplasma gondii Encystation and Persistence 2016
58 INVADIS Microbial invasion and dissemination within the host, mechanisms and effects 2016
59 BCM-UPS Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies 2016
60 ZMOD Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers 2016
61 Autonomous CLL-BCRs Role of autonomous B cell receptor signalling and external antigen in the pathogenesis of chronic lymphocytic leukaemia (CLL) 2016
62 IMMUNOALZHEIMER The role of immune cells in Alzheimer's disease 2016
63 iPSCAtaxia An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia 2016
64 AD-VIP Alzheimer’s disease and AAV9: Use of a virus-based delivery system for vectored immunoprophylaxis in dementia. 2016
65 HypoFlam Targeting hypothalamic inflammation in obesity and diabetes 2016
66 Foie Gras Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease 2017
67 DIAL-IN Dynamic Integrated structural and proteomic Analysis of the LUBAC complex and its involvement in NF-κB and inflammation 2016
68 PATHAD Pathways to Alzheimer's disease 2016
69 ZIKAction ZIKAction: Preparedness, research and action network on maternal-paediatric axis of ZIKV infection in Latin America and the Caribbean 2016
70 mtFOIE GRAS mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease 2017
71 miRCaP Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophy 2016
72 BONEPHAGY Defining the role of the FGF – autophagy axis in bone physiology 2017
73 MODulATE Gut microbiota-dependent tryptophan metabolism: role in disease pathogenesis and therapeutic target 2017
74 MYCONEUTROPHILS Elucidating the involvement of neutrophils in the pathogenesis of tuberculosis using a zebrafish model 2017
75 NEW-AGE A next-generation platform for catalysing pre-clinical development of drugs against Alzheimer’s and other degenerative diseases of old-age 2017
76 CARBOFLU Chemoenzymatic synthesis of complex glycans to decipher the interactions between them and Influenza A virus 2017
77 LamelliActin Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells 2017
78 PROZE Using a protein approach with Waddlia chondrophila and zebrafish as model organisms to conquer the female tubal factor subfertility market 2017
79 MIRA Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity 2017
80 REVERSING TAUOPATHY Identifying and deciphering the mechanism of the cellular machinery responsible for disaggregation of intracellular prion-like Tau aggregates 2017
81 REACT Uncovering the role of cis genetic elements in antigenic variation of Plasmodium falciparum using the CRISPR-Cas9 genome editing technology 2018
82 SupaSteD Suppresion of adaptive immunity by the Salmonella effector SteD 2017
83 ExItALS RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis 2017
84 MiRCHOL Mechanistic and therapeutic implications of microRNA deregulation for drug resistance in bile duct cancer 2017
85 HUNTINFISH Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets. 2018
86 PERISCOPE PERtussIS COrrelates of Protection Europe - Sofia ref.: 115910 2016
87 BEAt-DKD Biomarker Enterprise to Attack DKD - Sofia ref.: 115974 2016
88 PI3K-VAs Activation of PI3K signalling in the pathogenesis of Vascular Anomalies 2018
89 METCLL Discovery and validation of ‘epidrivers’ of cancer evolution and resistance to therapy 2018
90 ESCRT model A biophysical model for ESCRT-III mediated membrane scission 2017
91 HOST-SELECT Functional Analysis of Host Genetic Variants: Biomarker Selection Towards Improving Female Subfertility Diagnosis and Treatment 2017
92 IAV-m6A Elucidating the role of m6A RNA methylation on the replication and pathogenesis of influenza A virus. 2017
93 MRI-STRUCTURE MRI Signal To Recover Unique Cerebral TissUe Response to changEs 2018
94 DISMOD-HD Direct reprogramming for HD Disease Modelling 2017
95 OMPorg Spatiotemporal organisation of bacterial outer membrane proteins 2017
96 3DviralRNA Structural and functional characterization of large viral and human non-coding RNA motifs involved in HIV infection 2018
97 EpiFAT Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes 2017
98 GENDOSIS GENOTYPE - ENDOPHENOTYPE ASSOCIATIONS IN PSYCHOSIS 2017
99 iHEAR Investigating the meanings and mechanisms of psychotic experiences in young people: a novel, mixed-methods approach 2017
100 PIGSs Program for Innovative Global Prevention of Streptococcus suis. 2017
101 NAFLDcure A novel pharmaceutical treatment for nonalcoholic fatty liver disease 2017
102 FATE Functional Biology of Hepatic CD8+ T cells 2017
103 ENLIGHTEN INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION 2018
104 NEMESIS Neuron/mast cell interactions in skin diseases 2017
105 BrainDrain Translational implications of the discovery of brain-draining lymphatics 2017
106 EuroNeurotrophin A European training network for the discovery of neurotrophins small molecule mimetics as candidate therapeutic agents for neurodegeneration and neuroinflammation 2018
107 PD UpReg Gene knock-up via 3’UTR targeting to treat Parkinson’s disease 2017
108 LUPUSCARE PRECISION CARE IN SYSTEMIC AUTOIMMUNITY: AN INTEGRATED MULTI-TISSUE/LEVEL APPROACH FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) 2017
109 DecodingInfection Decoding the host-pathogen interspecies crosstalk at a multiparametric single-cell level 2017
110 deFIBER Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment 2018
111 CSI-Fun Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer 2018
112 AstroNeuroCrosstalk Astrocyte-Neuronal Crosstalk in Obesity and Diabetes 2018
113 DIAMONDCOR A molecular approach to treat diabetes mellitus onset dependent coronaropathy 2018
114 PyraSig Pyrazine Signalling in Commensal and Pathogenic Bacteria 2018
115 WISH WISH – Wearable Integrated System for Early Detection of Preterm Labour 2017
116 MRS in diabetes Novel methods in Magnetic Resonance Spectroscopy to investigate mechanisms underlying metabolic disease 2018
117 Damocles Modelling brain aneurysm to elucidate the role of platelets 2018
118 DynaMO_TB Spatiotemporal regulation of localization and replication of M. tuberculosis in humanmacrophages 2018
119 CLLCLONE Harnessing clonal evolution in chronic lymphocytic leukemia 2018
120 iPS-ChOp-AF Combining induced pluripotent stem cells, tissue engineering, optogenetic and chemogenetic concepts for the study and treatment of atrial fibrillation 2018
121 BIONICS A biomimetic and neuroprotective delivery nanocapsule for the targeted treatment of post-ischemic stroke effects 2018
122 Alpha-Synuclein Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. 2019
123 NEUROGUIDE Study of neuronal sensing and migration/guidance dynamics in neurodevelopmental disorders by nano-engineered chips 2018
124 TOPNIN Tracing of pulmonary neuro-immune networks 2018
125 cureCD Function of long non-coding RNA in Crohn Disease Ulcer Pathogenesis 2018
126 ImmunAID Immunome project consortium for AutoInflammatory Disorders 2018
127 HGB-StIC Human Genetic Basis of Severe Staphylococcal Infections in Childhood 2019
128 HifLICs Acute Myeloid Leukemia Leukemic Initiating Cells: Contribution of hypoxia/HIF pathway to chemoresistance and relapse 2019
129 MS-fMRI-QSM Studying Multiple Sclerosis with a novel simultaneous functional Magnetic Resonance Imaging (fMRI) and Quantitative Susceptibility Mapping (QSM) sequence. 2019
130 PREMNEC PReterm Enteroids to determine the Mechanism of Necrotising EnteroColitis 2018
131 IGpath Dissecting the functional pathways of B cell receptor immunoglobulin in antigen driven mature B cell lymphomas 2018
132 iNtoPoreAge Assessing transcriptional and nuclear pore aging in age-equivalent and rejuvenated induced neurons from Alzheimer patients 2019
133 Gut-AnorexiaNervosa Metagenomics and metabolomics studies of patients with Anorexia Nervosa to identify intestinal microbial mechanisms contributing to pathogenesis 2018
134 GLIAMAC Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation 2018
135 INFLA-AID The role of NLRC4 inflammasome in autoinflammatory diseases 2018
136 Neuronetmir Role of miR-129-5p and Rbfox1 crosstalk in neural network homeostasis 2018
137 NEVULA Understanding selective neuronal vulnerability in Alzheimer’s disease 2018
138 ProMeta Non-histone protein acetylation targets of KAT2A in AML 2018
139 NECROPTOSIS Necroptosis in immunity, inflammation and autoimmunity induced by nucleic acid sensors 2018
140 mTORmorS Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma 2019
141 ASSYSt A reliable CXCL4 biomarker assay to improve diagnosis and treatment of Systemic Sclerosis 2018
142 OrganoVIR Organoids for Virus Research - An innovative training-ETN programme 2019
143 HISTOID A Human iPS Cell-Derived Artificial Skeletal Muscle for Regenerative Medicine, Disease Modelling and Drug Screening 2018
144 FunHoMic Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections 2019
145 GLIOVACC Augmenting and broadening T-cell responses to glioblastoma - therapeutic vaccine platform based on HCMV expressing NKG2D ligands 2018
146 REMIND Targeting pathological synaptic pruning by microglia in neurodegeneration 2019
147 UPGRADE Unlocking Precision Gene Therapy 2019
148 IM2PACT Investigating Mechanisms and Models Predictive of Accessibility of Therapeutics (IM2PACT) Into The Brain 2019
149 DaPhNIs Role of the Maternal Gut Microbiota in Immune Activation at the Maternal-Foetal Interface: Impact on Preeclampsia and Offspring's Immune Development 2019
150 GEMMA Genome, Environment, Microbiome & Metabolome in Autism: an integrated multi-omic systems biology approach to identify biomarkers for personalized treatment and primary prevention of Autism Spectr 2019
151 ArthritisHeal Establishing the molecular fundamentals of arthritic diseases – a step forward to Heal Arthritis 2019
152 Epi4MS Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis 2019
153 ImmuNiche Identifying spatial determinants of immune cell fate commitment 2019
154 ADIMMUNE Decoding interactions between adipose tissue immune cells, metabolic function, and the intestinal microbiome in obesity 2019
155 DeCoCt Knowledge based design of complex synthetic microbial communities for plant protection 2019
156 RoBE Study of the role of BANK1 in antibody production and antibody-independent functions of B cells in SLE 2019
157 SeCRT Uncover mechanisms of unconventional secretion of tau using functional CRISPR screens - From basic discoveries to neurodegenerative disease therapeutics 2019
158 TRAIN-HEART TRAIN-HEART 2019
159 MagnetoVirology Diamond Magnetometry: A Versatile Tool for Virology and Medicine 2019
160 NeuroStemX In vitro model of Fragile X Syndrome using naïve iPSCs 2019
161 AstroCOMET Astrocyte-neuron COmmunication in METabolism and obesity. 2020
162 PMLingAML Using PML nuclear body biology to identify potential AML treatment targets 2020
163 GLYCOMENDO Non-invasive clinical markers for diagnosis of endometriosis 2019
164 SynGut Molecular, morphological, and functional requirements for gastrointestinal serotonin release 2020
165 CARDIATEAM CARdiomyopathy in type 2 DIAbetes mellitus 2019
166 StressOME Defining and modulating the stress granule proteome as a therapeutic strategy in Amyotrophic Lateral Sclerosis 2019
167 ROAR Role of endocycle in Acute Kidney Injury Response and Chronic Kidney Disease development 2019
168 T-NHL SUPRESSORS Tumor suppressor pathways counteracting oncogenic immune receptor signaling in T-Cell Lymphoma 2019
169 FunStructure Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease 2019
170 IMAGE-IN Imaging infections: integrated, multiscale visualization of infections and host response 2020
171 GWAS2FUNC From GWAS to functional studies: Tackling the complex nature of brain disorders 2019
172 CELLPHASE_AD Genetics to understand cellular components of Alzheimer Disease pathogenesis 2019
173 RECOGNISED Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia 2020
174 InterTAU Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease modifying drugs 2020
175 STRATIFY Diagnostic autoantibody assay to stratify bone marrow failure diseases 2020
176 nbPTMs A multifaceted platform for exploring nucleotide-based post-translational modifications 2021
177 CRISPRcombo Interrogating native CRISPR arrays to achieve scalable combinatorial screens and dissect genetic redundancy 2020
178 NanoGlia Understanding the impact of nanoplastics on the development of neurological disorders 2020
179 SILENT Silent mutations in cancer 2020
180 AimingT6SS Mechanisms of dynamic localization of the bacterial Type 6 secretion system assembly 2020
181 MyeRIBO Deconstructing the Translational Control of Myelination by Specialized Ribosomes 2020
182 STRATEGY-CKD System omics to unravel the gut-kidney axis in Chronic Kidney Disease. 2020
183 RARE MAPS Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease 2020
184 LINKER Elucidating transcriptional rewiring on hematological malignancies via computational methods 2020
185 C.A.R.E. OA Cross-linking Adenosine Receptors - Estrogen receptors for OA treatment 2021
186 TGF-BTB Transforming Growth Factor – Bench To Bedside. Towards a better understanding of TGF-β isoform specific signalling in health and disease 2020
187 DREAM Dux4-Regulated Expression and Activity by MATR3 2020
188 AlzheimersInAction AlzheimersInAction: A multi-disciplinary approach to determine the cellular and molecular mechanisms underlying the inflammatory response to amyloid-β in Alzheimer’s disease. 2021
189 LySyT Understanding the role of lysosomes in the intercellular TNT-mediated spreading of α-synuclein and the impact of lysosomal dysfunction 2020
190 POMOLIM Polycystic ovarian syndrome: novel molecular characterization and personalized in vitro maturation protocol. 2020
191 PRECISMEDLYM Aggressive T cell Lymphomas, integrated clinical and genomic analysis for a precision medicine. 2020
192 MAP-AD A multimodal approach to accelerate drug discovery and development in Alzheimer’s disease 2021
193 VirIVITES ARBOVIRUS SKIN INFECTION MODELLING FOR MORE ACCURATE VIRAL PATHOGENESIS 2020
194 TETCOLON Dissecting the role of the epigenetic regulator TET2 in colorectal cancer 2020
195 MUCO-IMMUN MUCOBIOME-MEDIATED IMMUNE PATHWAYS IN INFLAMMATORY BOWEL DISEASES 2020