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ErasmusBlink: A low cost and easy to use measurement system for medical research with diagnostic potential

Total Cost €


EC-Contrib. €






Project "ErasmusBlink" data sheet

The following table provides information about the project.


Organization address
postcode: 3015 GD

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 149˙938 €
 EC max contribution 149˙938 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2018-08-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Neuroscientists and clinicians use a wide range of behavioral tests to investigate the physiological mechanisms of learning and memory formation. One of the most objective and reliable tests is eyeblink conditioning, as it is extremely simple, it can be done in both humans and animals, it measures many aspects of how we learn in our daily life, and it can detect memory deficits in many neurological and psychiatric diseases. However, so far there are no low-cost reliable eyeblink conditioning setups commercially available. Therefore, we propose for this ERC-POC application to prepare the commercialization of ErasmusBlink as a low-cost, wearable eyeblink conditioning recording and analysis setup that can be used in virtually all species. With ErasmusBlink one can do reliable and reproducible eyeblink conditioning experiments for scientific, medical and industrial purposes. ErasmusBlink will be the first ‘total care’ package, alleviating the potential customer from the requirement of the technical and programming skills, which one currently needs to acquire before being able to do eyeblink conditioning experiments. Our market survey will cover three major fields: Basic neurosciences (1), clinical and pharmaceutical research (2), and nutritional sciences (3). For all three fields eyeblink conditioning parameters have been shown to uncover important and fundamental functional processes and correlations. Our current academic collaborations with key players in each of these disciplines and with industrial partners like Noldus IT serve as a solid platform to ensure a successful commercialization of ErasmusBlink.


year authors and title journal last update
List of publications.
2019 M.M. ten Brinke, H.J. Boele, C.I. De Zeeuw
Conditioned climbing fiber responses in cerebellar cortex and nuclei
published pages: 26-36, ISSN: 0304-3940, DOI: 10.1016/j.neulet.2018.04.035
Neuroscience Letters 688 2019-05-28
2016 Hille Koppen, Henk-Jan Boele, Inge H Palm-Meinders, Bastiaan J Koutstaal, Corinne GC Horlings, Bas K Koekkoek, Jos van der Geest, Albertine E Smit, Mark A van Buchem, Lenore J Launer, Gisela M Terwindt, Bas R Bloem, Mark C Kruit, Michel D Ferrari, Chris I De Zeeuw
Cerebellar function and ischemic brain lesions in migraine patients from the general population
published pages: 177-190, ISSN: 0333-1024, DOI: 10.1177/0333102416643527
Cephalalgia 37/2 2019-05-28
2018 Gili Ezra-Nevo, Francesca Prestori, Francesca Locatelli, Teresa Soda, Michiel M. ten Brinke, Mareen Engel, Henk-Jan Boele, Laura Botta, Dena Leshkowitz, Assaf Ramot, Michael Tsoory, Inbal E. Biton, Jan Deussing, Egidio D\'Angelo, Chris I. De Zeeuw, Alon Chen
Cerebellar Learning Properties Are Modulated by the CRF Receptor
published pages: 6751-6765, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.3106-15.2018
The Journal of Neuroscience 38/30 2019-05-28
2018 Devika Narain, Evan D. Remington, Chris I. De Zeeuw, Mehrdad Jazayeri
A cerebellar mechanism for learning prior distributions of time intervals
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-02516-x
Nature Communications 9/1 2019-05-28
2017 Karolina Löwgren, Rasmus Bååth, Anders Rasmussen, Henk-Jan Boele, Sebastiaan K. E. Koekkoek, Chris I. De Zeeuw, Germund Hesslow
Performance in eyeblink conditioning is age and sex dependent
published pages: e0177849, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0177849
PLOS ONE 12/5 2019-05-28
2017 Thomas M. Ernst, Markus Thürling, Sarah Müller, Fabian Kahl, Stefan Maderwald, Marc Schlamann, Henk-Jan Boele, Sebastiaan K. E. Koekkoek, Jörn Diedrichsen, Chris I. De Zeeuw, Mark E. Ladd, Dagmar Timmann
Modulation of 7 T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses
published pages: 3957-3974, ISSN: 1065-9471, DOI: 10.1002/hbm.23641
Human Brain Mapping 38/8 2019-05-28
2018 Anders Rasmussen, Anna C.H.G. Ijpelaar, Chris I. De Zeeuw, Henk-Jan Boele
Caffeine has no effect on eyeblink conditioning in mice
published pages: 252-255, ISSN: 0166-4328, DOI: 10.1016/j.bbr.2017.09.013
Behavioural Brain Research 337 2019-05-28
2017 Michiel M ten Brinke, Shane A Heiney, Xiaolu Wang, Martina Proietti-Onori, Henk-Jan Boele, Jacob Bakermans, Javier F Medina, Zhenyu Gao, Chris I De Zeeuw
Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.28132
eLife 6 2019-05-28
2017 Andrea Giovannucci, Aleksandra Badura, Ben Deverett, Farzaneh Najafi, Talmo D Pereira, Zhenyu Gao, Ilker Ozden, Alexander D Kloth, Eftychios Pnevmatikakis, Liam Paninski, Chris I De Zeeuw, Javier F Medina, Samuel S-H Wang
Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning
published pages: 727-734, ISSN: 1097-6256, DOI: 10.1038/nn.4531
Nature Neuroscience 20/5 2019-05-28

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