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DARWIN SIGNED

Dual capillary waveguide endoscope

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DARWIN project word cloud

Explore the words cloud of the DARWIN project. It provides you a very rough idea of what is the project "DARWIN" about.

device    modulator    wave    prototype    tissue    fibers    act    waveguide    guide    speed    cm    dispersion    tool    cladding    preliminary    experiments    signal    photoacoustic    light    neuron    darwin    fellow    endoscope    demonstrated    collect    dual    mode    illumination    remotely    patterns    detect    inside    proof    couples    detecting    outer    ratio    provides    optical    configurations    bending    transmission    guiding    prof    biological    bossy    vivo    frequency    overcome    sized    avoiding    detection    generation    collection    needle    attenuation    microscopy    effect    absorption    inserted    images    sound    waves    display    idea    diameter    explore    ultrasound    relies    matrix    modality    tip    excitation    thin    limiting    fluorescence    scattering    experiment    resolution    penetration    micron    invasively    team    hydrophone    compensation    acoustic    calibrate    capillary    core    alternative    single    scattered    fiber    imaging    distal   

Project "DARWIN" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE GRENOBLE ALPES 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE GRENOBLE ALPES FR (GRENOBLE) coordinator 173˙076.00
2    UNIVERSITE GRENOBLE ALPES FR (SAINT MARTIN D'HERES) coordinator 0.00

Map

 Project objective

Photoacoustic imaging, an emerging multi-wave imaging modality that couples light excitation to acoustic detection via the photoacoustic effect (sound generation via light absorption), relies on detecting ultrasound waves that are very weakly scattered in biological tissue. It provides acoustic-resolution images of optical absorption non-invasively at large depth (up to several cm). However, ultrasound attenuation increases with frequency, limiting the depth-to-resolution ratio to about 100. An alternative to overcome the dispersion of light in tissue due to scattering is using thin, micron-sized diameter optical fibers to both deliver and collect light from the sample. A novel idea and preliminary proof-of-concept experiment has just been demonstrated by Prof. Bossy’s team where a dual waveguide allows also to remotely detect high frequency ultrasound with the same device as that used for guiding light. This device can act both as a multi-mode optical waveguide for the illumination and fluorescence collection using the outer cladding, and as a waveguide to guide the ultrasound out of the tissue using the core, avoiding the absorption by the tissue and increasing the penetration depth.

The overall objective of DARWIN is to study and develop a new type of dual-modality endoscope for optical-resolution photoacoustic and fluorescence microscopy based on a capillary waveguide. To do so, a high speed phase modulator will measure the transmission matrix and calibrate the endoscope providing a way to display any optical patterns at the distal tip. The fellow will explore different configurations where a thin hydrophone, based on a single mode fiber or a needle, is inserted inside the core improving the acoustic signal detection. Furthermore, bending compensation will be investigated. DARWIN will result in a prototype thin endoscope for dual microscopy imaging, an important tool for in-vivo experiments, such as the neuron imaging.

 Publications

year authors and title journal last update
List of publications.
2018 Antonio M. Caravaca-Aguirre, Sakshi Singh, Simon Labouesse, Michael V. Baratta, Rafael Piestun, Emmanuel Bossy
Hybrid photoacoustic/fluorescence microendoscopy through a multimode fiber using speckle illumination
published pages: , ISSN: , DOI:
2020-02-13

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The information about "DARWIN" are provided by the European Opendata Portal: CORDIS opendata.

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