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DARWIN SIGNED

Dual capillary waveguide endoscope

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DARWIN project word cloud

Explore the words cloud of the DARWIN project. It provides you a very rough idea of what is the project "DARWIN" about.

speed    detect    excitation    dispersion    images    frequency    mode    collection    calibrate    optical    team    device    neuron    photoacoustic    penetration    waves    patterns    single    outer    vivo    inserted    effect    biological    idea    experiment    absorption    fellow    modulator    tool    hydrophone    cm    signal    limiting    attenuation    scattered    cladding    couples    microscopy    tip    endoscope    inside    display    sound    act    bossy    detection    scattering    experiments    prototype    capillary    bending    diameter    fluorescence    guide    ratio    resolution    wave    demonstrated    remotely    prof    configurations    transmission    waveguide    compensation    tissue    relies    sized    provides    acoustic    overcome    guiding    darwin    distal    micron    avoiding    fibers    needle    alternative    dual    light    core    explore    fiber    preliminary    illumination    thin    ultrasound    modality    collect    detecting    matrix    generation    imaging    proof    invasively   

Project "DARWIN" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE GRENOBLE ALPES 

There are not information about this coordinator. Please contact Fabio for more information, thanks.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE GRENOBLE ALPES FR (GRENOBLE) coordinator 173˙076.00
2    UNIVERSITE GRENOBLE ALPES FR (SAINT MARTIN D'HERES) coordinator 0.00

Map

 Project objective

Photoacoustic imaging, an emerging multi-wave imaging modality that couples light excitation to acoustic detection via the photoacoustic effect (sound generation via light absorption), relies on detecting ultrasound waves that are very weakly scattered in biological tissue. It provides acoustic-resolution images of optical absorption non-invasively at large depth (up to several cm). However, ultrasound attenuation increases with frequency, limiting the depth-to-resolution ratio to about 100. An alternative to overcome the dispersion of light in tissue due to scattering is using thin, micron-sized diameter optical fibers to both deliver and collect light from the sample. A novel idea and preliminary proof-of-concept experiment has just been demonstrated by Prof. Bossy’s team where a dual waveguide allows also to remotely detect high frequency ultrasound with the same device as that used for guiding light. This device can act both as a multi-mode optical waveguide for the illumination and fluorescence collection using the outer cladding, and as a waveguide to guide the ultrasound out of the tissue using the core, avoiding the absorption by the tissue and increasing the penetration depth.

The overall objective of DARWIN is to study and develop a new type of dual-modality endoscope for optical-resolution photoacoustic and fluorescence microscopy based on a capillary waveguide. To do so, a high speed phase modulator will measure the transmission matrix and calibrate the endoscope providing a way to display any optical patterns at the distal tip. The fellow will explore different configurations where a thin hydrophone, based on a single mode fiber or a needle, is inserted inside the core improving the acoustic signal detection. Furthermore, bending compensation will be investigated. DARWIN will result in a prototype thin endoscope for dual microscopy imaging, an important tool for in-vivo experiments, such as the neuron imaging.

 Publications

year authors and title journal last update
List of publications.
2018 Antonio M. Caravaca-Aguirre, Sakshi Singh, Simon Labouesse, Michael V. Baratta, Rafael Piestun, Emmanuel Bossy
Hybrid photoacoustic/fluorescence microendoscopy through a multimode fiber using speckle illumination
published pages: , ISSN: , DOI:
2020-02-13

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The information about "DARWIN" are provided by the European Opendata Portal: CORDIS opendata.

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