Opendata, web and dolomites

METAGE SIGNED

Metamorphosis as a re-set mechanism of the ageing clock: is early-life stress bypassed by morphogenesis?

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "METAGE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF GLASGOW 

Organization address
address: UNIVERSITY AVENUE
city: GLASGOW
postcode: G12 8QQ
website: www.gla.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-02-18   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF GLASGOW UK (GLASGOW) coordinator 183˙454.00

Map

 Project objective

The overall aim of this proposal is to understand how early-life stress can affect later ageing biomarkers (oxidative stress, telomere shortening, and telomerase activity) in species with complex life-cycles, and in particular to test the completely new hypothesis that amphibian metamorphosis may act to rejuvenate tissues previously exposed to stress. The research objectives are: 1) to determine whether levels of ageing biomarkers vary across larval and metamorphic stages, 2) to investigate whether damage accumulated by larvae due to early-stress is reduced by metamorphosis and whether this differ between remodelled and newly formed tissues/structures, and 3) to examine whether early-stress influences cellular responses stressors to ageing biomarkers later in life. I will be trained by the host to adopt an empirical approach to measuring early-life stress and ageing (e.g. oxidative stress, telomere length, and telomerase activity) in species with complex life-cycles (using as a model Xenopus laevis individuals), and will learn new skills in several areas of animal physiology and molecular biology, which are needed to successfully complete the research objectives. This training will increase my experience in different biological domains and will help me to develop my independent research group in the EU.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "METAGE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "METAGE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NeuroSens (2019)

Neuromodulation of Sensory Processing

Read More  

NPsVLCD (2019)

Natural Product-Inspired Therapies for Leishmaniasis and Chagas Disease

Read More  

POMOC (2019)

Charles IV and the power of marvellous objects

Read More