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CellFreeImplant SIGNED

Cell-free Ti-based Medical Implants due to Laser-induced Microstructures

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "CellFreeImplant" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT LINZ 

Organization address
address: ALTENBERGER STRASSE 69
city: LINZ
postcode: 4040
website: www.jku.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 100˙000 €
 EC max contribution 100˙000 € (100%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-4-2016-2017
 Funding Scheme CSA
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT LINZ AT (LINZ) coordinator 50˙000.00
2    BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG DE (BERLIN) participant 35˙000.00
3    KEPLER UNIVERSITATSKLINIKUM GMBH AT (LINZ) participant 15˙000.00

Map

 Project objective

New miniaturized and smart medical implants are more and more used in all medical fields, including miniaturized pacemakers. These implants with a casing consisting often of a Ti-alloy may have to be removed after some months or several years and shall therefore not be completely overgrown by the cells. In the framework of the ongoing FET Open project LiNaBioFluid, we successfully demonstrated that self-organized sharp cones or spikes at Ti-alloy substrates created by pulsed laser-ablation can result not only in complete wetting by water and body fluids but at the same time provide too little surface for the cells (i.e., fibroblasts) to grow on. Compared to flat surfaces, the cell density on the microstructures is significantly lowered, the coverage is incomplete and the cells have a clearly different morphology. The best results regarding suppression of cell growth are obtained on structures created by femtosecond Ti:sapphire laser irradiation, which are subsequently electrochemically treated. The goal of the Coordination and Support Action CellFreeImplant is to find strategic partners (end-users) for future development of smart medical implants addressing wide-spread patients needs for instance in the field of cardio-vascular diseases. The project activities include the identification of the market segments and needs and assessment of the technology with end-users.

 Publications

year authors and title journal last update
List of publications.
2019 L. Caldero
Surface Functionalization with LIPSS Continues to Expand into New Industries
published pages: 9 -11, ISSN: , DOI:
LIA TODAY Newsletter 27/4 (July/August 2019) 2020-02-20
2018 P. Fosodeder, M. Muck, W. Baumgartner, A. Weth, C. Steinwender, A.W. Hassel, J. Heitz
Laser-Structured and Anodized Ring around Ti Cylinders as barrier against Overgrowth by Fibroblasts
published pages: II - III, ISSN: , DOI:
Journal für Kardiologie - Austrian Journal of Cardiology 25 (11–12_online) 2019-06-27

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The information about "CELLFREEIMPLANT" are provided by the European Opendata Portal: CORDIS opendata.

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