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CheSSTaG SIGNED

Chemotactic Super-Selective Targeting of Gliomas

Total Cost €

EC-Contrib. €

Partnership

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CheSSTaG project word cloud

Explore the words cloud of the CheSSTaG project. It provides you a very rough idea of what is the project "CheSSTaG" about.

associating brain repertoire components engineering responsive safe nervous carrier therapeutic drug propelled arising structural combine biological inspired equipping interaction function physiological self characterisation functional payload gradients completely nanoparticles glucose biodegradable final clinically integrate cells cancer form polymersomes harbouring toward gradient platform complement supramolecular healthy super carriers complexity tools central chemotactic barrier selective molecular

Project "CheSSTaG" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	2˙081˙747 €
EC max contribution	2˙081˙747 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2017-COG
Funding Scheme	ERC-COG
Starting year	2018
Duration (year-month-day)	from 2018-05-01 to 2023-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	2˙081˙747.00

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Project objective

I propose here a research program aimed to the design a completely new platform for drug delivery. I will combine our existing repertoire of molecular engineering tools based around our established approach to design responsive nanoparticles known as Polymersomes to integrate new features using clinically safe and biodegradable components that will make them super-selective and chemotactic toward glucose gradients so to deliver large therapeutic payload into the central nervous systems and the brain in particular targeting cancer cells harbouring within the healthy. We will do so by engineering components using supramolecular interaction inspired by biological complexity equipping carriers with the ability to self-propelled as a function of glucose gradient. I will complement our proposed design with advanced biological characterisation associating functional information arising form the physiological barrier to structural parameters integrated into the final carrier design.

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The information about "CHESSTAG" are provided by the European Opendata Portal: CORDIS opendata.