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EARLYRIDERS SIGNED

Tracking the temporal and geographic origins of modern domestic horses

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 EARLYRIDERS project word cloud

Explore the words cloud of the EARLYRIDERS project. It provides you a very rough idea of what is the project "EARLYRIDERS" about.

question    techniques    scalable    content    transfer    genome    archaeological    wave    source    dna    transmitted    pathogens    instance    transmission    agriculture    temporal    horse    unknown    originating    trade    load    vector    spread    sequence    poorly    found    pathogen    gap    riders    domestication    societies    domestic    epizootic    contagious    vectors    form    sequencing    passively    locus    interconnected    larger    bronze    human    earlyriders    warfare    thousands    strains    despite    researcher    absent    full    haunted    geographic    hyrad    age    diseases    either    transport    populations    rapid    horses    disease    plague    dating    earliest    revolutionizing    accounted    forged    endogenous    centers    riding    gene    appears    moderate    history    turning    samples    serious    epidemiology    hundreds    concurrent    enrichment    allowed    humans    ancestors    interplay    300    shows    loci    point    subjected    modern    fleas    ancient   

Project "EARLYRIDERS" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PAUL SABATIER TOULOUSE III 

Organization address
address: ROUTE DE NARBONNE 118
city: TOULOUSE CEDEX 9
postcode: 31062
website: www.ups-tlse.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) coordinator 173˙076.00

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 Project objective

The goal of the EARLYRIDERS project is to identify the geographic and temporal locus of modern horse domestication. It also focuses on the interplay between domestication and the increase of pathogen load in horses, and the role of epizootic transfer of human pathogens, especially plague. Horse domestication represents a turning point in human history, revolutionizing transport, trade, warfare, agriculture, and allowing humans to form larger, interconnected societies. Despite its importance for human history, this process remains poorly understood. Recent genome sequencing shows that the earliest archaeological remains of domestic horses are not the ancestors of modern domestic horses and that another, still unknown, wave of domestication forged the modern horse during the Early Bronze Age. Horse riding also allowed a rapid spread of diseases. For instance, the plague, that regularly haunted human populations in history, has been already commonly found in human remains dating to the Early Bronze Age. As the gene essential for the transmission through fleas was absent in these ancient strains, the plague might have been transmitted through other, still unknown vectors. This represents a serious gap in understanding of the early epidemiology of this important disease. As the spread of plague appears to be concurrent to horse domestication, the question remains whether the horse accounted for its spread, either as a vector or passively, by contagious riders. We aim at identifying the source of the second domestication wave and pathogen load in ancient horse populations by sequencing 300 samples originating from all potential centers of domestication. Full genome sequencing is not possible due to low endogenous DNA content, therefore the samples will be subjected to sequence enrichment techniques, including the novel hyRAD method developed by the experienced researcher, scalable to thousands of loci in hundreds of samples at moderate cost.

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