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PredOpt SIGNED

Neural circuits for optimal prediction of timing

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "PredOpt" data sheet

The following table provides information about the project.

Coordinator
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM 

Organization address
address: DR MOLEWATERPLEIN 40
city: ROTTERDAM
postcode: 3015 GD
website: www.erasmusmc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2020-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) coordinator 177˙598.00

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 Project objective

Predicting the timing of events is not only crucial to our survival but seamlessly contributes to everyday activities like riding bicycles, dancing or playing sports. Human and animal prediction of timing is statistically optimal, however, how such behavior arises from neural circuitry is poorly understood. Here I outline a theoretical framework, testable hypotheses and a set of experiments that will help uncover the neural circuits that integrate previous experience to make optimal estimates about the timing of events. In this proposal, the systematic investigation of optimality in complex forms of timing behavior is based on exploiting known neural circuits belonging to simple timing behavior. The anatomical origins of simple timing tasks like eyeblink conditioning are extremely well-characterized in the cerebellum of different species. Using this, I propose a framework for extending this circuit to understand optimal timing in a series of targeted physiology, behavior and optogenetics experiments. This research, if successful, will reveal the neural basis for how the nervous system combines previously encountered stimuli and recent observations to generate statistically optimal estimates and will generate valuable insights into the underpinnings of biological intelligence.

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The information about "PREDOPT" are provided by the European Opendata Portal: CORDIS opendata.

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