Opendata, web and dolomites


Selective Functionalization of Saturated Hydrocarbons

Total Cost €


EC-Contrib. €






 BioMet project word cloud

Explore the words cloud of the BioMet project. It provides you a very rough idea of what is the project "BioMet" about.

selectively    always    activation    tremendously    transformed    isomerize    shift    alkene    chemical    chemically    skeleton    added    mutated    hydrometalation    stronger    ing    first    petroleum    subsequently    bonds    metal    strain    invention    engaged    chemists    feedstock    gas    trapping    alkanes    carbon    reaction    minus    favor    electrophiles    materials    distinguish    hydrocarbons    raw    hydrocarbon    equivalent    terminus    substrate    chemistry    molecular    despite    organometallic    feedstocks    expense    natural    performed    efficient    converting    valorize    formed    centuries    position    constituents    removal    weaker    migration    derivatives    variety    standard    species    atoms    benign    functionalized    sequence    double    inert    representing    catalyzed    synthesis    hydrogen    intermediates    alkane    paradigm    ideally    remaining    synthetic    preparation    bond    sciences    functionalization    primary    logic    saturated    desired    organic    represented    environmentally    cheap    compounds    architectures    rhodococcus    secondary    selective    geometry    effect    puzzled   

Project "BioMet" data sheet

The following table provides information about the project.


Organization address
city: HAIFA
postcode: 32000

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 2˙499˙375 €
 EC max contribution 2˙499˙375 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-ADG
 Funding Scheme ERC-ADG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Despite that C–H functionalization represents a paradigm shift from the standard logic of organic synthesis, the selective activation of non-functionalized alkanes has puzzled chemists for centuries and is always referred to one of the remaining major challenges in chemical sciences. Alkanes are inert compounds representing the major constituents of natural gas and petroleum. Converting these cheap and widely available hydrocarbon feedstocks into added-value intermediates would tremendously affect the field of chemistry. For long saturated hydrocarbons, one must distinguish between non-equivalent but chemically very similar alkane substrate C−H bonds, and for functionalization at the terminus position, one must favor activation of the stronger, primary C−H bonds at the expense of weaker and numerous secondary C-H bonds. The goal of this work is to develop a general principle in organic synthesis for the preparation of a wide variety of more complex molecular architectures from saturated hydrocarbons. In our approach, the alkane will first be transformed into an alkene that will subsequently be engaged in a metal-catalyzed hydrometalation/migration sequence. The first step of the sequence, ideally represented by the removal of two hydrogen atoms, will be performed by the use of a mutated strain of Rhodococcus. The position and geometry of the formed double bond has no effect on the second step of the reaction as the metal-catalyzed hydrometalation/migration will isomerize the double bond along the carbon skeleton to selectively produce the primary organometallic species. Trapping the resulting organometallic derivatives with a large variety of electrophiles will provide the desired functionalized alkane. This work will lead to the invention of new, selective and efficient processes for the utilization of simple hydrocarbons and valorize the synthetic potential of raw hydrocarbon feedstock for the environmentally benign production of new compounds and new materials.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BIOMET" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BIOMET" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

NanoPD_P (2020)

High throughput multiplexed trace-analyte screening for diagnostics applications

Read More  

NeuroMag (2019)

The Neurological Basis of the Magnetic Sense

Read More  

FuncMAB (2019)

High-throughput single-cell phenotypic analysis of functional antibody repertoires

Read More