Opendata, web and dolomites

BioMet SIGNED

Selective Functionalization of Saturated Hydrocarbons

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 BioMet project word cloud

Explore the words cloud of the BioMet project. It provides you a very rough idea of what is the project "BioMet" about.

alkane    atoms    constituents    position    representing    added    first    subsequently    ideally    desired    converting    variety    selectively    expense    activation    metal    valorize    performed    selective    derivatives    benign    always    stronger    organometallic    efficient    double    chemically    synthetic    species    hydrocarbon    petroleum    cheap    terminus    invention    hydrocarbons    strain    bond    saturated    standard    removal    alkanes    logic    mutated    carbon    hydrometalation    sequence    represented    alkene    bonds    molecular    primary    engaged    substrate    minus    environmentally    remaining    reaction    puzzled    compounds    chemists    feedstocks    materials    paradigm    skeleton    migration    ing    feedstock    hydrogen    gas    electrophiles    distinguish    rhodococcus    isomerize    intermediates    weaker    trapping    favor    chemistry    despite    geometry    tremendously    catalyzed    functionalized    transformed    synthesis    architectures    preparation    effect    secondary    organic    natural    formed    shift    inert    sciences    centuries    chemical    raw    functionalization    equivalent   

Project "BioMet" data sheet

The following table provides information about the project.

Coordinator
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY 

Organization address
address: SENATE BUILDING TECHNION CITY
city: HAIFA
postcode: 32000
website: www.technion.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 2˙499˙375 €
 EC max contribution 2˙499˙375 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-ADG
 Funding Scheme ERC-ADG
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) coordinator 2˙499˙375.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Despite that C–H functionalization represents a paradigm shift from the standard logic of organic synthesis, the selective activation of non-functionalized alkanes has puzzled chemists for centuries and is always referred to one of the remaining major challenges in chemical sciences. Alkanes are inert compounds representing the major constituents of natural gas and petroleum. Converting these cheap and widely available hydrocarbon feedstocks into added-value intermediates would tremendously affect the field of chemistry. For long saturated hydrocarbons, one must distinguish between non-equivalent but chemically very similar alkane substrate C−H bonds, and for functionalization at the terminus position, one must favor activation of the stronger, primary C−H bonds at the expense of weaker and numerous secondary C-H bonds. The goal of this work is to develop a general principle in organic synthesis for the preparation of a wide variety of more complex molecular architectures from saturated hydrocarbons. In our approach, the alkane will first be transformed into an alkene that will subsequently be engaged in a metal-catalyzed hydrometalation/migration sequence. The first step of the sequence, ideally represented by the removal of two hydrogen atoms, will be performed by the use of a mutated strain of Rhodococcus. The position and geometry of the formed double bond has no effect on the second step of the reaction as the metal-catalyzed hydrometalation/migration will isomerize the double bond along the carbon skeleton to selectively produce the primary organometallic species. Trapping the resulting organometallic derivatives with a large variety of electrophiles will provide the desired functionalized alkane. This work will lead to the invention of new, selective and efficient processes for the utilization of simple hydrocarbons and valorize the synthetic potential of raw hydrocarbon feedstock for the environmentally benign production of new compounds and new materials.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BIOMET" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BIOMET" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

HyperCube (2020)

HyperCube: Gram scale production of ferrite nanocubes and thermo-responsive polymer coated nanocubes for medical applications and further exploitation in other hyperthermia fields

Read More  

EVOCELFATE (2019)

Evolution of cell fate specification modes in spiral cleavage

Read More  

Diverge (2019)

Generation of ultra-deep libraries of transcriptional activators for gene therapy

Read More