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iFermenter SIGNED

iFERMENTER - CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROTEINS BY INTELLIGENT FERMENTATION

Total Cost €

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EC-Contrib. €

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Partnership

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Project "iFermenter" data sheet

The following table provides information about the project.

Coordinator
NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU 

Organization address
address: HOGSKOLERINGEN 1
city: TRONDHEIM
postcode: 7491
website: www.ntnu.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 5˙362˙320 €
 EC max contribution 3˙997˙825 € (75%)
 Programme 1. H2020-EU.3.2.6.1. (Sustainable and competitive bio-based industries and supporting the development of a European bio-economy)
 Code Call H2020-BBI-JTI-2017
 Funding Scheme BBI-RIA
 Starting year 2018
 Duration (year-month-day) from 2018-05-01   to  2022-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU NO (TRONDHEIM) coordinator 928˙150.00
2    TECHNISCHE UNIVERSITAET WIEN AT (WIEN) participant 673˙266.00
3    UNIVERSITAT DES SAARLANDES DE (SAARBRUCKEN) participant 613˙875.00
4    BIO BASE EUROPE PILOT PLANT VZW BE (DESTELDONK GENT) participant 438˙473.00
5    UNIVERSITAET ULM DE (ULM) participant 409˙875.00
6    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) participant 250˙395.00
7    INFORS AG CH (BOTTMINGEN) participant 229˙875.00
8    UNIVERSIDAD DE SANTIAGO DE COMPOSTELA ES (SANTIAGO DE COMPOSTELA) participant 179˙390.00
9    NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET NO (AS) participant 146˙500.00
10    MYBIOTECH GMBH DE (UBERHERRN) participant 128˙025.00
11    BORREGAARD AS NO (SARPSBORG) participant 0.00
12    GALACTIC SA BE (ESCANAFFLES) participant 0.00

Map

 Project objective

Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and contribute to a sustainable bioeconomy. Unfortunately, existing biorefineries struggle with technical issues and low profitability due to the lack of adequate fermentation processes. Therefore, these sugars are either incinerated to generate energy or at best converted to ethanol (€0.6 /kg) but not to higher value chemicals. Current concepts that aim to establish fermentation processes to convert residual sugar streams to high value products face challenges including inefficient sugar utilization by microorganisms and inhibitors in the residual streams, leading to low productivity and yields. Our project aims to recover high value compounds from sugar residuals, and to turn fermentation processes converting these residual to antimicrobials cost effective. We will recover the high value sugar galactose (€40-200 /kg) from residual streams as part of their treatment process. By genome editing technique, we will design cell factories that consume the remaining residuals and produce nisin (€50-150 /kg), an industrially important commercial food/feed preservative. Additionally, we will develop an affordable, online feedback add-on system that will allow to intelligently change residual mixture during fermentation of these cell factories to optimize production online during the process. In a 150 L industrial bioreactor, we will demonstrate that our add-on invention iFermenter - increases the yields of nisin by over 2 fold - increases the nisin production by over 50% compared to what is possible today, - and reduce at least 20% in CO2 footprint with this process compared to existing solutions. Thus, iFermenter will render production of high value products with residual sugar stream highly efficient and cost-effective contributing to circular economy.

 Deliverables

List of deliverables.
External website of iFermenter Websites, patent fillings, videos etc. 2020-04-09 20:08:42
Initial Environmental impact assessment Documents, reports 2020-04-09 20:08:36

Take a look to the deliverables list in detail:  detailed list of iFermenter deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Andrea Tuveri, Pedro LIra, Fernando Perez-Garcia, Nadav Bar
EXTENDED KALMAN FILTER FOR SUGAR ESTIMATION USING COMBINED FREQUENT AND INFREQUENT MEASUREMENTS
published pages: , ISSN: , DOI:
IFAC FOSBE 19 17th October 2019 2020-03-06
2019 Peter Sinner, Julian Kager, Sven Daume, Christoph Herwig
Model-based Analysis and Optimisation of a Continuous Corynebacterium glutamicum Bioprocess Utilizing Lignocellulosic Waste
published pages: , ISSN: 2405-8963, DOI:
IFAC-PapersOnLine 2020-03-06
2019 Ingvild S. Reinseth, Kirill V. Ovchinnikov, Hanne H. Tønnesen, Harald Carlsen, Dzung B. Diep
The Increasing Issue of Vancomycin-Resistant Enterococci and the Bacteriocin Solution
published pages: , ISSN: 1867-1306, DOI: 10.1007/s12602-019-09618-6
Probiotics and Antimicrobial Proteins 2020-03-06

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The information about "IFERMENTER" are provided by the European Opendata Portal: CORDIS opendata.

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